Top 10 Hardest Enemies to Kill in Resident Evil 5

thousandfk

The Top TenXW

1Cockroaches (Reapers)

Giant cockroaches are a lot harder than I thought because they are a lot worse than a chainsaw zombie in Resident Evil 5! The best way to kill this pest is trying to use mines or finish it off with a Gatling gun if you unlock it!

these things gave me more hell than all of the others combined. I despise these creatures so much. one hit and your dead. plus without a magnum or Rck Lchr your screwed. - thousandfk

I agree that these are one of the hardest but you just need the first to third handgun to win. You need to stock up on at least 60 shots (including fully loaded clip). Run and get some space I shoot the left arm first but that's just a preference of mine than I wait till it falls on the other arm before I shoot than I wait till the chest infection spore pops out of the armor than spam my reloaded clip (I reload a lot laugh out loud) if you miss a couple of shots (3 or more) it'll beweakened but get back up.

Wow these top tens get really specific - marmalade_skies

V1 Comment
2Licker

these guys are a pest because if they stick their tongue in you, it's game over. - thousandfk

V1 Comment
3Clam

this is actually the majini that transforms into a big clam like mosnter with a huge mouth and a ribcage for a tail. it picks you up and eats you if you get to close to it. - thousandfk

You will die, no kidding, the only thing to kill them is by shooting their annoying tail.

Actually, these monsters that looks like a crab-like clam are Duvalias! If your on a dying status and that Duvalia grabs you, then all that is left of you is your legs and bottom! You should either shot the legs or tail of the Duvalia and then you could shoot the opening of the beast and it will be terminated!

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4Fat Black Majini

this majini takes the form of a fat black man with no shirt on and if he hits you, your in trouble. - thousandfk

V1 Comment
5Ndesu

this is the big troll thing ( el gigante RE4) EVERYBODY CLAIMS THAT HE IS SOO TOUGH TO BEAT. he's actually not that difficult. learn to stop the big flying boulder he throws at you and you should be fine. - thousandfk

This guy is prity hard laugh out loud:-) No healing, silly button pressing, computer ai is really bad (Sheva sucks). Managed to do it on my 4th attempt with co-op play, this guy is bad ass, add turnerboythe2nd on psn if you need help with this brute of a boss, easily the hardest guy in the game:-( Fat maj guys are easy compared to troll guy on level 2.3 on pro

You guys are all confused n uv been throwing your ammo away- just look up RE5 stat lists n you'll see how 2 cream everything cept ndesu. The clam? You mean duvalia- head (no damage) appendage (10% damage) legs (full damage), mouth (150% damage) EASY, just shoot em in the legs til they open their mouth, then make em eat lead. Reaper? Legs, arms or head (no damage), stomach (full damage), not so easy... fact is, everything has a weak spot, but don't listen to anyone else's advice on this page, you'll just be wasting your ammo.

V2 Comments
6Wesker

this guy is a badass. he's really not that bad, as long as you have infinite rocket launcher. otherwise you'll be stuck all night. - thousandfk

He can be easy, challenging, or downright insanely difficult to fight with, depending on how you approach the fight. You'll battle Albert 4 times in the entire campaign, first in the Monarch room, then in the Missile facility, third inside the assault stealth bomber (QTE) style, and finally in the volcano, which is also the hardest. Word of advice, make sure you have plenty of ammo, particularly a magnum and an RPG, also be good in QTE, there'll be plenty of them. Good luck!

7Gatling Guys

I find them pretty easy to tend to, even on Professional, just don't get caught with a lot of other enemies with them or they can down you very quick. Shotgun or Magnum shots to the head are very effective against them plus it gives you an opportunity to unleash a devastating combo melee on him/them.J.J. is his more common name, but you can call also refer to him as a gatling gun guy, but for me he's dead meat.

these guys carry ginormous gatling guns on their backs and on professional one hit puts you into dying mode and another ceases your existence. - thousandfk

8Sunlight Laser Beams

these are in chapter 4-2 and for some reason I had a really rough time getting past these things. I finally just got my friend to blow them up with rocket launcher - thousandfk

Don't get caught on its path, or its curtains for you. Best way to deal with it is to hide whenever you hear it coming and try to locate it's handler and eliminate him to get rid of this weapon.

9Jill

Pretty much a frustrating fight, especially on harder difficulties (veteran & pro) as Jill can deal massive damage on you or your AI partner sometimes even leave you in dying status. Word of advice try to stay away from her then approach stealthily from behind to restrain her. Be attentive to QTEs as you'll be spending most of the time doing it. Make sure to stock up on health items just in case. Word of advice, don't use magnum or shotgun when shooting her chest device as it can kill her resulting in a game over. Handguns and rifles are safer and much better. Patience is your best weapon here.

yeah thats right. this beeyatch is going straight to hell. it took me and my friend 3 and a half hours to beat her on professional. it was insanely difficult. she is single handedly the hardest boss fight I've ever played and the worst part about it is you can't shoot her! - thousandfk

Also use the flash rounds. It blinds her and gives you a chance to restrain her.

10Irving

Long and grueling battle, be prepared for it. Be patient and shoot him with either the mounted guns or rocket launchers on the boat or just use your ammo. However you deal with him be wary of his tentacles or where he may pop out and watch out for QTEs as well and make him come out of the monsters mouth to deal real damage on him, if you have an RPG unload 1 on him to finish the fight.

he can be a real pain in the ass. make sure you have the infinite rocket launcher and he's not that bad. no infinite rocket launcher = no beating irving. - thousandfk

The Contenders

11Excella Gionne

It took longer to beat her than weaker and Jill she was tough

The only thing to destroy it, is with the target locater. And the thing keeps moving before you get a chance to lock on to its weakpoints. Also is instant kill is really annoying.

12Verdugo
13Chainsaw Guy

This guy is so hard to kill! He is fast and he can behead me when he is close. The best way to kill it is a magnum of the RPG. Land mines also helps.

14Del Lago
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