1 Discord - My Little Pony: Friendship Is Magic
Discord, also known as the Spirit of Disharmony, is a former-antagonist-turned-supporting-protagonist in My Little Pony: Friendship is Magic. But if there is a Discord, shouldn't there be a Harmony to make things equal and if there are the elements of harmony, there has to some sort of elements of discord? I'm just wondering.
Torn between Discord and Bill Cipher, but ever since the Season 6 finale, I realized how amazing this guy is
He's better than the Ice King from Adventure Time
2 Aku - Samurai Jack
Aku is a fictional character and the main antagonist of Samurai Jack, an American animated television series created by Genndy Tartakovsky for Cartoon Network. "Fool! Oh, fun fact. That was the last remaining time portal in existence! "
3 Megatron - The "Transformers" Franchise
Megatron is a character from the Transformers franchise, created by Hasbro in 1984, based on a toy design by Takara. No other villains is this cool or notorious than megaton
4 The Shredder - The "TMNT" Franchise
5 Mojo Jojo - The Powerpuff Girls
Mojo Jojo is a fictional character from the American animated television series, The Powerpuff Girls, created by animator Craig McCracken for Cartoon Network.
6 Dr. Heinz Doofenshmirtz - Phineas and Ferb
Dr. Heinz Doofenshmirtz is a fictional character and the main antagonist from the animated television show Phineas and Ferb. He was created by Dan Povenmire and Jeff "Swampy" Marsh, and is voiced by Povenmire. Doofenshmirtz is absolutely hilarious
7 Slade - Teen Titans
Slade is a fictional incarnation of the character Deathstroke in the American animated series Teen Titans and is the archenemy of the Teen Titans, who wants them destroyed for his own unknown reasons, and is the main antagonist of Season 1 and Season 2; He appears as a vision in Season 3, returned only as a loyal and devoted minion of the mighty demon Trigon in Season 4, he also makes a small appearance in the final episode of Season 5 "Things Change." He also appears as the main antagonist of Teen Titans Go to the Movies. He was voiced by Ron Perlman and Will Arnett. He is also the arch-nemesis of Robin.
8 Plankton - Spongebob Squarepants
Sheldon James Plankton, or simply Plankton, is a character in the Nickelodeon animated television series SpongeBob SquarePants.
9 Sideshow Bob - The Simpsons
Dr. Robert Underdunk Terwilliger, better known as Sideshow Bob, is a recurring character in the animated television series The Simpsons. The show's nature means they are allowed to portray villainous characters sympathetically, so they're most likely to make at least one likable. Here, we feel sorry for this oft-abused character. Even when he isn't up to anything, he still gets treated pretty badly, even getting arrested when he didn't do anything ("Brother From Another Series", Season 8). Plus he has a lot of personality.
10 Princess Azula - Avatar: The Last Airbender
She was psychotic! But respectably devious and evil!
The Contenders
11 Bill Cipher - Gravity Falls
Bill Cipher is a triangular dream demon formerly existent only in the mindscape who wished to gain access to the real world. He has been running amok in Gravity Falls, Oregon since being summoned by Stanford Pines over thirty years ago. He is known for his mysterious demeanor and sadistic humor. He is the main antagonist of Gravity Falls, although he doesn't play a central role in the series until season 2. Bill Cipher is probably one of the funniest villains ever, His unique personality deserves him to be on the top.
12 Zim - Invader Zim
Zim is the titular protagonist and anti-hero of the American animated series Invader Zim, created by Jhonen Vasquez for Nickelodeon.
13 Ice King - Adventure Time
He is such a lovable guy, you can't really hate him.
14 Dr. Gero - Dragon Ball Z
15 Magica De Spell - DuckTales (2017)
16 Anti Cosmo - The Fairly Oddparents
17 Edward Bighead - Rocko's Modern Life
18 Eric Cartman - South Park
Eric Theodore Cartman, often referred to just by his surname, is a main character, as well as a major antagonist and occasional antihero in the animated television series South Park, created by Matt Stone and Trey Parker, and voiced by Parker. He is one of four central characters in South Park, along with Stan Marsh, Kyle Broflovski, and Kenny McCormick. Cartman first appeared, originally in prototypical... read more
19 Peridot - Steven Universe
Peridot is from the show Steven Universe created by Rebecca Sugar. The show airs on Cartoon Network and has grown in popularity over the years. The character Peridot is an alien gem from a planet called Homeworld, Peridot is introduced in the episode "Marble Madness," when Steven and the Crystal Gems ...read more.
20 Atlas - Astro Boy (2003)
21 Queen Beryl - Sailor Moon
22 Vlad Plasmius - Danny Phantom
Vladimir "Vlad" Masters (also known as Vlad Plasmius) is the main antagonist from the American animated series Danny Phantom created by Butch Hartman for Nickelodeon. He is Danny's arch-enemy and Jack Fenton's former best friend and Maddie's former lover. He is voiced by Martin Mull.
23 Denzel Crocker - Fairly Odd Parents
Denzel Quincy Crocker is a fictional character from the American animated series The Fairly OddParents created by Butch Hartman for Nickelodeon. He is the mentally unstable school teacher of Timmy and is one of the main antagonists in the series.
24 Him - The PowerPuff Girls
25 Professor Calamitous - The Adventures of Jimmy Neutron: Boy Genius
Professor Finbarr Calamitous (simply known as Professor Calamitous) is a fictional character and the main antagonist of The Adventures of Jimmy Neutron: Boy Genius.