1 Eric Cartman - South Park
Eric Theodore Cartman is one of the main characters in the animated television series South Park, created by Matt Stone and Trey Parker, and voiced by Trey Parker.
The best South Park character.
2 Stewie Griffin - Family Guy
Stewart Gilligan "Stewie" Griffin is a main character from the animated television series Family Guy. Obsessed with violence and matricide, Stewie is the youngest child of Peter and Lois Griffin, and the brother of Meg and Chris Griffin.
He is the coolest baby in all animated comedies.
3 Bender - Futurama
Bender Bending Rodríguez is a fictional robot who is a main character in the animated television series Futurama. He was created by series creators Matt Groening and David X. Cohen and is voiced by John DiMaggio.
The bad robot is probably the most memorable character on Futurama.
4 Homer Simpson - The Simpsons
Homer Jay Simpson is the protagonist of the American animated television series The Simpsons as the patriarch of the eponymous family.
He is the most reconisible animated comedy character.
5 Roger - American Dad
6 Peter Griffin - Family Guy
Peter Griffin is the main protagonist and titular character of the American animated sitcom Family Guy.
The main character of Family Guy is not as cool as Homer but still funny.
7 Sterling Archer - Archer
8 Bart Simpson - The Simpsons
Bart is the oldest child in The Simpsons. He was created by Matt Greoning. His hobbies are pranking people including Lisa Simpson and Homer Simpson.
This prank-pulling daredevil is a great character.
9 Zoidberg - Futurama
Hillarious way funnier than Bender
10 Philip J. Fry - Futurama
11 Tina Belcher - Bob's Burgers
She says just the weirdest and funniest things.
12 Amy Wong - Futurama
13 Stan Smith - American Dad
Stanford Leonard "Stan" Smith is the main protagonist of the adult animated sitcom American Dad!. He is voiced by the series' co-creator and executive producer, Seth MacFarlane.
The best American Dad character
14 Ralph Wiggum - The Simpsons
Ralph Wiggum is a side character in The Simpsons. He is the son of Chief Wiggum. Ralph is not very smart at all. He is voiced by Nancy Cartwright. Some episodes such as I Love Lisa and This Little Wiggy have him as a major character.
15 Louise Belcher - Bob's Burgers
16 Maggie Simpson - The Simpsons
Margaret "Maggie" Simpson is a fictional character in the animated television series The Simpsons. She first appeared on television in the Tracey Ullman Show short "Good Night" on April 19, 1987. Maggie was created and designed by cartoonist Matt Groening while he was waiting in the lobby of James L. ...read more.
17 Tim the Bear - The Cleveland Show
18 Bob Belcher - Bob's Burgers
19 Patrick Star - SpongeBob SquarePants
Patrick Star is a fictional character in the American animated television series SpongeBob SquarePants. He is voiced by actor Bill Fagerbakke, who also voices numerous other characters on the show . Created and designed by marine biologist and cartoonist Stephen Hillenburg, the series creator, Patrick ...read more.
20 Rocko - Rocko's Modern Life
Rocko is the eponymous fictional character of the cartoon Rocko's Modern Life and the comic book series of the same name.
21 Squidward - Spongebob Squarepants
Squidward Tentacles is a fictional character voiced by actor Rodger Bumpass in the American animated television series SpongeBob SquarePants.
22 Lisa Simpson - The Simpsons
Lisa Marie Simpson is a fictional character in the animated television series The Simpsons. She is the middle child and most intelligent of the Simpson family.
Basically the complete opposite of Bart.
23 Krusty the Clown - The Simpsons
Krusty the Clown is a clown from The Simpsons. He first appears in the short Krusty the Clown, but in the show he first appears in The Telltale Head. He is Jewish. Despite the fact that he is children's entertainer, he seen drinking and smoking a lot.
24 Meg Griffin - Family Guy
Megan "Meg" Griffin is a character from the animated television series Family Guy, voiced initially by Lacey Chabert, thereafter by Mila Kunis.
25 Soos - Gravity Falls
26 The Cheese - Rocko's Modern Life
27 Leopold Butters Stotch - South Park