Best Anime With Adult Protagonists

The Top Ten
1 Steins;Gate Steins;Gate is a 2011 anime television series created by the animation studio White Fox based on 5pb. and Nitroplus's 2009 video game of the same name, and is part of the Science Adventure franchise.
2 Cowboy Bebop Cowboy Bebop is a 1998 anime television series animated by Sunrise featuring a production team led by director Shinichirō Watanabe, screenwriter Keiko Nobumoto, character designer Toshihiro Kawamoto, mechanical designer Kimitoshi Yamane, and composer Yoko Kanno.
3 One Punch Man One-Punch Man is an ongoing, online, web comic, which was later adapted into a Manga and Anime series . Created by ONE in 2009, It gained popularity, and soon after, went viral in 2012, surpassing 7 . 9 million views . One-Punch Man (OPM for short) focuses on the protagonist Saitama (Who is named after the prefecture Saitama) as he goes on to find someone who has power even remotely close to his,... read more
4 Samurai Champloo Samurai Champloo is a Japanese anime series developed by Manglobe. Samurai Champloo is set in an alternate version of Edo-era Japan with an anachronistic, predominantly hip hop, setting. It follows Mugen, an impudent and freedom-loving vagrant swordsman; Jin, a composed and stoic rōnin; and Fuu, a brave girl who asks them to accompany her in her quest across Japan to find the "samurai who smells... read more
5 Darker than Black Darker than Black, known in Japan as Darker than Black: The Black Contractor, is an anime television series created, directed and written by Tensai Okamura and animated by Bones. In 2007, the 26 episode anime named Darker Than Black: The Black Contractor aired with a huge commercial success. It was followed by the sequel Darker Than Black: Gemini of the Meteor in 2009... read more
6 Hellsing Hellsing is a Japanese manga series written and illustrated by Kouta Hirano. It premiered in Young King OURs in 1997 and ended in September 2008.
7 Death Parade Death Parade is a 2015 Japanese anime television series created, written, and directed by Yuzuru Tachikawa and produced by Madhouse.
8 Trigun Trigun is a Japanese manga series written and illustrated by Yasuhiro Nightow. The manga was serialized in Tokuma Shoten's Shōnen Captain in 1995 with three collected volumes when the magazine was discontinued in 1997.
9 Spice and Wolf Spice and Wolf is a Japanese light novel series written by Isuna Hasekura, with illustrations by Jū Ayakura.
10 Mushishi Mushishi is a manga series written and illustrated by Yuki Urushibara. It was serialized in Afternoon Seasons Zōkan from 1999 to 2002, and in Monthly Afternoon from December 2002 to August 2008. The individual chapters were collected and released into ten tankōbon volumes by Kodansha.
The Contenders
11 Hellsing Ultimate Hellsing is a Japanese manga series written and illustrated by Kouta Hirano. It chronicles the efforts of the mysterious and secret Hellsing Organization, as it combats vampires, ghouls, and other supernatural foes who threaten England.
12 Black Lagoon Black Lagoon (stylized in all caps) is a Japanese manga series written and illustrated by Rei Hiroe. It has been published in Shogakukan's seinen manga magazine Monthly Sunday Gene-X since April 2002, with its chapters collected in twelve tankōbon volumes as of August 2021. In North America, the manga is licensed for English release by Viz Media... read more

Nearly everyone in this show is an adult

13 Tokyo Ghoul Tokyo Ghoul is a Japanese dark fantasy manga series written and illustrated by Sui Ishida. It was serialized in Shueisha's seinen manga magazine Weekly Young Jump between September 2011 and September 2014, and it has been collected in fourteen tankōbon volumes as of August 2014.

Well technically Kaneki is an adult since he's 19 and a university student

14 Yuri on Ice Yuri!!! on Ice is a sports anime television series about figure skating. The anime was produced by MAPPA, directed by Sayo Yamamoto and written by Mitsurō Kubo.
15 Barakamon
16 Terror in Resonance
17 Sakura Quest
18 Dragon Ball Z Dragon Ball Z is a Japanese anime television series produced by Toei Animation. Dragon Ball Z follows the adventures of Goku who, along with the Z Warriors, defends the Earth against evil. The action adventures are entertaining and reinforce the concept of good versus evil. Dragon Ball Z teaches valuable character virtues such as teamwork, loyalty, and trustworthiness.
19 Berserk Berserk, also known as Sword-Wind Chronicle Berserk, is a Japanese anime television series that aired from 1997 to 1998. An adaptation of the manga Berserk, it comprises 25 half-hour episodes produced by Oriental Light and Magic and first aired on Nippon TV.
20 Bungou Stray Dogs
21 The Rising of the Shield Hero
22 Vinland Saga Vinland Saga (Japanese: ヴィンランド・サガ, Hepburn: Vinrando Saga) is a Japanese historical anime series based on the manga of the same name written and illustrated by Makoto Yukimura. The story dramatizes the journey of Thorfinn Karlsefni and his expedition to find Vinland. The majority of the story covers his fictional counterpart's transition from a bloodthirsty, revenge-filled teenager... read more
23 Odd Taxi
24 Gregory Horror Show
25 Merman in My Tub
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