Top 10 Best Anime with a Female Protagonist

The Top Ten

Ghost in the Shell
Moribito: Guardian of the Spirit
Psycho-Pass Psycho-Pass is an anime television series that was produced by Production I.G, directed by Naoyoshi Shiotani & Katsuyuki Motohiro and written by Gen Urobuchi.
Sailor Moon Sailor Moon is a Japanese shōjo manga series by Naoko Takeuchi. It was originally serialized in Nakayoshi from 1991 to 1997; the 52 individual chapters were published in 18 tankōbon volumes. ...read more.
Puella Magi Madoka Magica Puella Magi Madoka Magica is a 2011 Japanese anime television series produced by Shaft and Aniplex, directed by Akiyuki Shinbo, written by Gen Urobuchi, music by Yuki Kajiura, opening sang by ClariS, ending by Kalafina (sometimes by the seiyuus) and original characters by Ume Aoki.
Yona of the Dawn Yona of the Dawn is a Japanese manga series by Mizuho Kusanagi, serialized in Hakusensha's shōjo manga magazine Hana to Yume from August 2009. It has been collected in twenty tankōbon volumes.

Great character development. Weak to strong. Surrounded by guys. Who wouldn’t like it?

Tamayura
Azumanga Daioh
Magical Girl Lyrical Nanoha Magical Girl Lyrical Nanoha is a Japanese anime television series directed by Akiyuki Shinbo, with screenplay written by Masaki Tsuzuki, and produced by Seven Arcs.
Non Non Biyori

The Newcomers

? Girls' Last Tour
? Kemono Friends Kemono Friends is a television anime series produced by Kadokawa, based on the smartphone game created by Nexon.

The Contenders

Blood-C
HeartCatch PreCure Heartcatch Precure is a Japanese anime series and the seventh series of the Pretty Cure anime franchise by Izumi Todo that premiered on February 7, 2010, replacing Fresh Pretty Cure! on its initial timeslot. The series theme is flowers, which leads to their true definitions of Hanakotoba as of the season's ...read more.
Cardcaptor Sakura Cardcaptor Sakura, abbreviated as CCS and also known as Cardcaptors, is a Japanese shōjo manga series written and illustrated by the manga group Clamp.
Yuru Yuri
K-On! K-ON! (けいおん!, literally 'Light Music') is a Japanese slice of life and comedy four-panel comic strip manga written and illustrated by Kakifly. It was serialized from 2007 to 2012, and there are six volumes to the manga in total. Kyoto Animation produced the anime adaptation, which aired over ...read more.
Ergo proxy Ergo Proxy is a science fiction suspense anime television series, produced by Manglobe, directed by Shukō Murase and written by Dai Satō.
ViViD Strike!
Mai-Hime
Shakugan no Shana Shakugan no Shana is an anime series including three television series, original video animation episodes, and bonus shorts.
Save Me Lollipop!
Claymore Claymore is a dark fantasy manga series written and illustrated by Norihiro Yagi. The series initially premiered in the now defunct Monthly Shōnen Jump in the May 2001 issue, but was moved to one of their sister magazines as the content was deemed too adult for Shōnen Jump’s target demographic.
Medaka Box
WataMote
Jūsō Kikō Dancouga Nova
Squid Girl
Black Lagoon
Kaichou Wa Maid Sama Maid Sama! is a shōjo manga series by Hiro Fujiwara. It is serialized in Hakusensha's monthly shōjo manga magazine, LaLa. There are currently 18 published volumes under the Hana to Yume Comics imprint in Japan.
Maria Holic
Lucky Star Lucky star is an anime that first aired (april 8th, 2007 to September 16th, 2007) in Japan. The anime follows the daily lives of Konata Izumi, Kagami and Tsukasa hiiragi, and Miyuki Takura. The show is best known for the cute "moe" characters. The target audience is shouen.
Made in Abyss
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