1 Big Daddy - BioShock
2 Reyn - Xenoblade Chronicles
"Just goes to show; BRAWN is better than brains! " - xandermartin98
3 DK - Donkey Kong Country
4 Heavy Weapons Guy - Team Fortress 2
Heavy is awesome - bobbythebrony
5 Goro - Mortal Kombat
Goro is a fictional character from the Mortal Kombat fighting game series. He first appears in the original Mortal Kombat as an unplayable boss character, challenging the player before the final fight with Shang Tsung.
6 Beast Ganon - The Legend Of Zelda
7 Onox - The Legend Of Zelda: Oracle Of Ages
8 Blanka - Street Fighter
9 Iron Knuckle - The Legend Of Zelda: Ocarina Of Time
10 Giga Mac - Punch-Out!
11 Wario - Super Mario Bros.
Wario is a character in Nintendo's Mario series who was originally designed as an antagonist to Mario. His motives are driven by greed and he will take the side of whoever will give him the most pay. Although he may seem like just a mean man with no heart, he does have a very tragic past.
12 Giant Clank - Ratchet & Clank
13 Shao Kahn - Mortal Kombat
Shao Kahn is a boss, announcer, and recurring playable character from the Mortal Kombat fighting game series. Introduced in Mortal Kombat II in 1993, he is the primary antagonist of the video game series and extended franchise.
14 Flint - Mother 3
15 Marcus Fenix - Gears Of War
Marcus Michael Fenix is a fictional character and the primary protagonist from Gears of War video game series.
16 Barrett - Final Fantasy Vii
17 Duke Nukem - Duke Nukem
18 Fassad - Mother 3
19 Funky Kong - Donkey Kong Country
20 Sabin - Final Fantasy VI
21 Exdeath - Final Fantasy V
22 Gorons - The Legend Of Zelda
23 Hulk - The Incredible Hulk
Robert Bruce Banner, also known as The Hulk or Bruce Banner, is a fictional superhero appearing in American comic books published by Marvel Comics. The character was created by Stan Lee and Jack Kirby and was portrayed by Edward Norton and Mark Ruffalo in the Marvel Cinematic Universe.
24 Zangief - Street Fighter
25 Murray - Sly Cooper
26 Brick - Borderlands
27 Krieg - Borderlands 2
28 Salvador - Borderlands 2
29 Bowser - Super Mario Bros.
Bowser is the main antagonist of the Mario Bros. Franchise. From kidnapping Princess Peach to simply destroying a fun game between Mario and Friends in the Mario Party spinoff series, this king of the Koopas has set up a certain hatred towards himself amongst the large cast of Mario Characters. He first ...read more.
30 Big Sister - BioShock 2
31 Subject Delta - BioShock 2
32 Balrog - Cave Story
33 Balrog - Street Fighter
34 King Hippo - Punch-Out!
King Hippo is a fictional boxer from Nintendo's Punch-Out!! series. King Hippo first appeared on the Nintendo Entertainment System game Mike Tyson's Punch-Out!!, as the second competitor in the Major Circuit.
35 King K. Rool - Donkey Kong Country
36 Dog - Half-Life 2
37 Giga Bowser - Super Smash Bros.
38 Goron Link - The Legend Of Zelda: Majora's Mask
39 Captain Quark - Ratchet & Clank
40 Kintaro - Mortal Kombat 2
41 Motaro - Mortal Kombat 3
Motaro is a fictional character in the Mortal Kombat fighting game series. He made his first appearance as a sub-boss character in Mortal Kombat 3, where he has the legs of a horse and the torso of a man.
42 Nappa - Dragon Ball Z
43 Super Mutant - Fallout 3
44 Frank Fontaine (Final Boss) - BioShock
45 Steroid Joker - Batman: Arkham Asylum
46 Ralph - Wreck-it Ralph
47 Steroid Knights - Castle Crashers
48 Pyramid Head - Silent Hill 2
49 Knuckles - Sonic Boom
Knuckles the Echidna is a fictional character in Sega's Sonic the Hedgehog series. He is a red anthropomorphic echidna who is determined and serious, but sometimes gullible. He has the ability to glide and climb up walls, and is a powerful fighter due to his spiked hands.
The only problem I have with Sonic Boom Knuckles is that they made him a bit out of character by making him stupid. He is supposed to be smart (not as smart as Tails, but still far from stupid), not dumb as a rock. Having him buff is fine, as it's a contrast to Sonic's speed, but making him dumb just isn't right.
50 Lance Banson - Henry Hatsworth in the Puzzling Adventure