1 Caillou - Caillou
2 Angelica Pickles - The Rugrats
Angelica Pickles is a cartoon character who appears in the Nickelodeon shows Rugrats, All Grown Up!, and Rugrats Pre-School Daze, and is among one of the series' original characters.
3 D.W. Read - Arthur
4 Sheila Broflovski - South Park
Stupid Sheila Broflovski is NOT a cartoon character and she was never a cartoon character because she’s dead
5 Peppa Pig - Peppa Pig
6 Maleficent - Sleeping Beauty
7 Cruella De Vil - 101 Dalmatians
Cruella de Vil is a fictional character who appeared in Dodie Smith's 1956 novel The Hundred and One Dalmatians, Disney's animated film adaptations 101 Dalmatians and 101 Dalmatians II: Patch's London Adventure, and Disney's live-action film adaptations 101 Dalmatians and 102 Dalmatians as the main ...read more.
8 Mom - Futurama
9 Yzma - The Emperor's New Groove
Yzma is the royal adviser of Emperor Kuzco in 'The Emperor's New Groove'. She is also a mad potions master and after being fired by Kuzco, she tries to use her potions to get rid of him and instate herself as empress.
10 Pretty - Kaeloo
She's literally the worst character on this show. She just makes fun of people for being poor and/or ugly, and she does all sorts of terrible things like shooting a horse because she liked unicorns better, forcing her sister's boyfriend to marry her (for the sake of getting a ring and a dress), beating Stumpy up for no apparent reason and revealing Kaeloo and her friends' embarrassing secrets to the public.
While Kaeloo's a great show, Pretty is one of the worst characters on it. Unlike the other antagonists who have at least a few redeeming qualities, she has none and spends her time picking on other people including her own twin.
Kaeloo is nothing but nice to Pretty, and Pretty humiliates her in public for no reason. Pretty also says she "loves" Mr. Cat, but she doesn't care about him beyond his looks and she doesn't care that he doesn't reciprocate his feelings.
She’s even worse than Kaeloo, Stumpy, Mr. Cat and Olaf put together and multiplied by ten!
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11 Loretta Brown - Family Guy
12 Mammy Two Shoes - Tom & Jerry
13 Lola Bunny - The Looney Tunes
Lola Bunny is a Looney Tunes cartoon character portrayed as an anthropomorphic female rabbit. She is Bugs Bunny's girlfriend. She was created as "female merchandising counterpart" to Bugs Bunny. She first appeared in the 1996 film Space Jam
14 Connie D'Amico - Family Guy
I expect she throws tantrums to get her own way!
I imagine if her car was the wrong colour, she might throw a spoiled, 2 year old tantrum. If I had a Fanfics account, I shall write a fanfic about her basis for my Inside Out OC Tiffany (Riley's bully) and how her sweet 16 turned sour due to her car being the wrong colour/brand and how she blamed Riley for it!
15 Paulina - Danny Phantom
16 Dodie Bishop - As Told By Ginger
17 Kyle's Mom - South Park
18 Kaeloo - Kaeloo
There was an episode where Kaeloo decided to make Quack Quack, her "precious angel", eat some weird organic food which tasted really bad, just because "it's good for the environment". Quack Quack refuses to eat it, so she force-feeds it to him. Quack Quack vomits it out. Instead of understanding that vomiting in disgust is a normal reaction, Kaeloo beats him as a punishment for "wasting food".
I know she's supposed to be the protagonist, but she can be really annoying at times. Mr. Cat and Stumpy are better characters.
She's easily the least likable of the main four and actually the whole cast besides Pretty.
Heaven forbid someone should actually be better than Kaeloo at something! She once rigged a game show Mr. Cat was going on so that he would lose, just because he told her he was always right about everything and she wanted him to lose so he'd be proven wrong. There was also this episode where she went on a reality T.V. show which was about singing and got kicked out because she was bad at singing, and instead of accepting that the others were better, she kept coming back to the studio and forcing everyone to listen to her singing.
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19 Lisa Simpson - The Simpsons
Lisa Marie Simpson is a fictional character in the animated television series The Simpsons. She is the middle child and most intelligent of the Simpson family.
20 Rigby - Regular Show
Rigby is a character from the cartoon Regular Show created by JG Quintel. He's best friends with Mordecai (A talking Blue Jay). Together they slack around and have fun in the park. A place where they work and have the risk of being fired from.
21 Trixie Tang - Danny Phantom
22 Trixie Tang - The Fairly OddParents
23 Diamond Tiara - My Little Pony: Friendship is Magic
Thank God She Reformed - JPK
24 Muffy Crosswire - Arthur
25 Meg Griffin - Family Guy
Megan "Meg" Griffin is a character from the animated television series Family Guy, voiced initially by Lacey Chabert, thereafter by Mila Kunis.
26 The Ashleys - Recess
27 Princess - Harvey Beaks
28 Shelly Marsh - South Park
29 Brit and Tiff - My Life as a Teenage Robot
30 Lila Sawyer - Hey Arnold!
Lila Sawyer is a fictional character from the 90s Nickelodeon cartoon Hey Arnold created by Craig Bartlett. She's generally known for being nice and kind to her classmates which disgusts Helga Pataki. She also has a crush on Arnold's cousin Arnie. In the series she's revealed to be poor next to being ...read more.
I'm the only one who actually LIKE her? - Garoto_Oceano
31 Lizzie DeVine - Codename: Kids Next Door
32 Dora - Dora the Exlorer
Dora is the main protagonist in the show "Dora the Explorer". Her main occupation is exploring with her monkey friend, Boots.
33 Trina Riffin - Grojband
Trina Riffin is a main antagonist from Canadian show, GrojBand. She is Corey Riffin's older sister who has anger issues. She has a crush to Nick Mallory. She hates GrojBand with burning passions. Corey sometimes pissed her by ruining her good day to go to diary mode so he can steal her diary for his ...read more.
34 Briar Beauty - Ever After High
She is too girly. Enough, said.
35 Rachel - Les Sisters
She picks on Wendy for no reason, and not just that, she also picks on Marine even though she’s just a little girl.
36 Leni Loud - Loud House
Leni Loud is a fictional character from The Loud House the second oldest of the Loud Family a bit of a ditz, forgetful and absent minded despite this she's a kindhearted person, a skilled fashion designer and is always willing to help others in need, she shares a room with Lori the oldest and suffers ...read more.
37 Brandy - Brandy and Mr. Whiskers
38 Darla Dimple - Cats Don't Dance
I hate Darla Dimple so much and she is NOT a cartoon character and she was never a cartoon character. I’m very happy that jerk is dead for good
39 Nefera de Nile - Monster High