1 Homer Simpson
Homer Jay Simpson is the protagonist of the American animated television series The Simpsons as the patriarch of the eponymous family.
Homer Simpson is lame, unfunny, try hard, etc... They all look weird and speak slow. They need to learn how to keep their scenes short and sweet. And the main character Homer isn't really funny, he's humorous for 9-12 year old's only. - Boi_bye
You gotta admit: Homer is completely superior.
They do fight though in the griffins meet the simpsons - YOSHIA2121
For ripping-off his show - BlueDiamondFromNowhere
2 Goku (DBZ)
Son Goku (Kakarrot) is the main protagonist in Dragon Ball franchise created by Akira Toriyama in 1984. He has many abilities like, super strength, utilization of ki, flight, teleportation, super speed, enhanced reflexes, and Super Saiyan transformation that increase strength, speed, and durability. ...read more.
3 Stan Smith
Stanford Leonard "Stan" Smith is the main protagonist of the adult animated sitcom American Dad!. He is voiced by the series' co-creator and executive producer, Seth MacFarlane.
Well he knows fighting strategies
No Peter should beat up him! - RockStarr
4 Michael Myers
Michael Myers is a character from the Halloween series of slasher films. He first appears in John Carpenter's Halloween as a young boy who murders his older sister, then fifteen years later returns home to murder more teenagers. ...read more.
With the sound of terror
5 Meg Griffin
Megan "Meg" Griffin is a character from the animated television series Family Guy, voiced initially by Lacey Chabert, thereafter by Mila Kunis.
Yeah she should beat Peter up for all of things that he did to her.
Peter has beat up Meg a lot, so Meg will do her revenge!
6 Clara Oswald
Clara Oswald was one the companions to the 11th and 12th Doctors. Her actor is Jenna Coleman. Her first appearance is "Asylum of the Daleks" and her last is "Twice Upon a Time".
No way! Stewie should beat up lois not peter!
It's Pikachu, not Pichachu.
Unless a Pokemon is made and is called that.
Mario is the main character in the Mario Bros. Franchise, who was created by the creative director and video game designer at Nintendo of Japan, Shigeru Miyamoto. Mario has appeared in almost every Mario Game, including spinoff series, as a playable character, with few exceptions including New Super ...read more.
With the right power-ups... Peter wouldn't stand a chance.
Mario should jump on him
With his firepower.
Hey, Nintendofan126. please go check out Top 10 Reasons Why Super Mario Galaxy is Bad.
10 Eva (Total Drama)
11 Infinite (Sonic Forces)
12 Luffy (One Piece)
13 Wreck-It Ralph
14 Teridax (Bionicle)
15 Gru (Despicable Me)
Felonius Gru is the main character of Despicable Me, Despicable Me 2, and Despicable Me 3, alongside Mel and a minor character in Minions.
17 Angry Video Game Nerd
James Duncan Rolfe is an American actor, comedian, filmmaker, film and video game critic, and internet personality, best known for starring in the web television series The Angry Video Game Nerd, a joint production of Rolfe's Cinemassacre Productions, GameTrailers, and ScrewAttack.
He will turn Peter into a crappy video game and make a very negative review on it.
avgn loves family guy
Sans or Sans the Skeleton is a character in the 2015 RPG Undertale created by Toby Fox. He is a lazy, pun-loving skeleton who is a supporting protagonist in the "pacifist" and "neutral" routes of Undertale, and a heroic antagonist/final boss of the "genocide" route. He is known for his incredibly difficult ...read more.
No Sans should be Strangled
20 Guts Man
The Slender Man is a fictional supernatural character that originated as an Internet meme created by Something Awful forums user Eric Knudsen
22 Amy Rose
Amy Rose is a fictional character in SEGA's Sonic the Hedgehog series. She is a pink anthropomorphic hedgehog with a cheerful, competitive personality, and is infatuated with the series' main character, Sonic. She serves as the first playable female character in the series.
Yeah, you go girl.
Waluigi is a lanky self-centered, brusque young lad as he is considered evil and the main rival of Luigi. Waluigi is shown causing local havoc in most games he appears in alongside his partner Wario. Waluigi is not instinctively evil or the antagonist (not counting DDR), as a matter of fact, he shows ...read more.
WALUIGEE number ONE
24 Jerry (Tom and Jerry)
Jerry Mouse is a fictional character and one of the title characters in Metro-Goldwyn-Mayer's series of Tom and Jerry theatrical cartoon short films. He is a mouse that gets chased by Tom, but tries to trick him so he won't catch him .
25 Ernie the Giant Chicken