1 Lisa Simpson
Lisa Marie Simpson is a fictional character in the animated television series The Simpsons. She is the middle child and most intelligent of the Simpson family.
Unlike Lisa, Uncle Grandpa is stupid and arrogant and does not use the voice of reason when dealing with serious matters. - TwilightKitsune
Mangle is a character from Five Nights at Freddy's. She has a yellow eye and a black eye. She is designed as a broken fox.
3 Princess Celestia
He deserve it for going on terrible adventures and having a dumb show - Discord1
They can beat up this pedophalic retard and show him that it is wrong to maltreat your friends. - TwilightKitsune
Send him to the moon! - nko32
It is just a kid show TwilightKitsune (it may not be a very good kid show) so there is no need for violence - Israelbooker
Yeah but Uncle Grandpa is ruining Cartoon Network so we have to use violence to get him out. - TwilightKitsune
4 Princess Luna
5 Nicole Watterson
She can easily beat up Uncle Grandpa
6 Spitfire (My Little Pony)
Of course! Spitfire is one of my favorite Pegasus ponies. Go get em'! - Chromium
7 Princess Cadence (My Little Pony)
She is the one of the three main characters in the show The Powerpuff Girls. She was first created by Craig McCracken in 1992. She has short raven hair and green eyes with a green dress. She is known as the "toughest fighter" for her tomboyish attitude, being aggressive, and her love for fighting crime. ...read more.
Buttercup is awesome! She's so much better than that phony Rainbow Dash and a heroine and awesome. - TwilightKitsune
Buttercup should beat uncle grandpa up. Uncle grandpa sucks, buttercup is a billion times better than him.
Buttercup should beat up Pizza Steve too. She's awesome. - TwilightKitsune
9 Gohan - Dragon Ball Z
Son Gohan is a fictional character in the Dragon Ball manga series created by Akira Toriyama. Gohan is introduced as the first son of the protagonist Goku, and his wife Chi-Chi, in chapter #196 Kakarrot, first published in Weekly Shōnen Jump magazine on October 24, 1988. Chi-Chi is a strict and protective ...read more.
Gohan is my favourite character and he is a better friend to his friends than UG is to his. - TwilightKitsune
Definitely! Gohan is a pacifist though, I doubt that he would beat up anyone unless they are really evil and kill too many of his loved ones. - Goku02
Pikachu are a species of Pokémon, fictional creatures that appear in an assortment of video games, animated television shows and movies, trading card games, and comic books licensed by The Pokémon Company, a Japanese corporation.
Thank you Pikachu for making my childhood awesome and I hate Uncle Grandpa for ruining people's childhood. Please beat him up. - TwilightKitsune
I love UG but I agree with this just because Pikachu beating up Uncle Grandpa would be the most hilarious thing ever.
Berserker is a fictional character from the Japanese visual novel and anime series Fate/stay night by Type-Moon. Berserker can refer to two different Berserker-class servants: Lancelot from Fate/Zero and Heracles from Fate/stay night.
12 Blaze The Cat
Blaze will roast him over an open flame, letting his corpse fall down while it is burnt. - TwilightKitsune
Uncle Grandpa is gonna need some ice for that burn. OH
Pearl was completely disgusted with Uncle Grandpa. I fail to see why they would crossover great shows like Steven Universe with crappy ones like Uncle Grandpa. - TwilightKitsune
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14 Darth Vader
Darth Vader was the original dark lord for Star Wars. Darth Vader ruled with both fear and aggression. Originally Anakin Skywalker a young Jedi who was then seduced by the dark side of the force by Chancellor Palpatine/Darth Sidious. Vader had his limbs cut off by his jedi master Obi-Wan Kenobi leaving ...read more.
Uncle Grandpa has failed Vader for the Last Time. So Vader grabbed his Lightsaber and killed Uncle Grandpa. - ChroniclerMan5
I love Marceline she says what she feels throughout her songs which are sometimes really emotional and moving. - TwilightKitsune
Mario, go stomp on that stupid, Patrick-voiced person who can't get a life like Johnny Test - bugger
17 Zim (Invader Zim)
Zim is the titular protagonist and anti-hero of the American animated series Invader Zim, created by Jhonen Vasquez for Nickelodeon. V 1 Comment
18 Bill Cipher - Gravity Falls
Bill Cipher is a triangular dream demon formerly existent only in the mindscape who wished to gain access to the real world. He has been running amok in Gravity Falls, Oregon since being summoned by Stanford Pines over thirty years ago. He is known for his mysterious demeanor and sadistic humor. He ...read more.
He should be in the top ten. - Discord1
19 Hatsune Miku
Hatsune Miku, sometimes referred to as Miku Hatsune, is a humanoid persona voiced by a singing synthesizer application developed by Crypton Future Media.
20 Barney The Dinosaur
Barney The Dinosaur is a purple dinosaur from the TV series "Barney and Friends", as well as the VHS series before that known as "Barney and the Backyard Gang". He was created by Sheryl Leach in 1987, to entertain her 2 year old son. He is infamously known for his "I Love You" song, and his TV series ...read more.
Since Barney is a pedophile, you'll know what he will do to Uncle Grandpa
They'll probably go out with eachother since they both are pedophiles. - Skullkid755
Barney will rape Uncle Grandpa
IA is a humanoid persona voiced by a singing synthesizer application developed by 1st Place Co., Ltd., headquartered in Meguro, Japan. They use Yamaha Corporation's Vocaloid 3 singing synthesizer technology. Her voice is sampled by Lia.
IA is awesome, her look is the best, also her voice is so cool.
Force him to listen to super loud music - Discord1
My favourite vocaloid - TwilightKitsune
22 Gru - Despicable Me
Gru is the main protagonist in the Despicable me movies and is voiced by Steve Carell. Gru was formerly a supervillain until he found three little girls he adopted.
He was first introuduce in 2010
Freeze him with the freeze ray - Discord1
He could use the Lipstick Tazer
23 Maxwell (Scribblenauts)
Maxwell should create a lava pool or other deadly things that should kill Uncle Grandpa - bugger
24 Homer Simpson
26 Alucard (Hellsing)
Uncle Grandpa would beg for mercy as he rips him apart limb by limb
27 Rainbow Dash
Rainbow Dash is a female Pegasus pony from the popular 2010 kid's show My Little Pony: Friendship is Magic. She represents the element of loyalty is one of most well known characters of the show.
She may be a little mean sometimes but she still does what is best for her friends .
She Will Sonic Rainboom Into Uncle Grandpa
Please Respect My Opinion TwilightKitsune
28 Utatane Piko
Utatane Piko is a Japanese speaking Vocaloid by Sony Entertainment for Vocaloid 2. He is based on the Japanese singer Piko. V 1 Comment
29 Steve (Minecraft)
Murder him with a diamond sword. - Discord1
30 Eric Cartman
Eric Theodore Cartman is one of the main characters in the animated television series South Park, created by Matt Stone and Trey Parker, and voiced by Trey Parker.
He'll Curse At Uncle Grandpa
31 Amy Rose
Piko Piko Hammer.
32 Rouge The Bat
33 Oliver (Vocaloid)
Chainsaw him - Discord1
34 Felonius Gru
He could use the Lipstick Tazer
35 Mr. Gus
He will Betray Uncle Grandpa - Discord1
36 Giant Realistic Flying Tiger
37 Tako Luka
38 Kamui Gakupo
Slice him with swords - Discord1
He should send him to another dimension - Discord1
40 Hibiki Lui
41 Megurine Luka
Megurine Luka is a humanoid persona voiced by a singing synthesizer application developed by Crypton Future Media, headquartered in Sapporo, Japan.
42 Luke Skywalker
Luke Skywalker is a fictional character appearing as the central protagonist of the original film trilogy, and as a supporting character in the sequel trilogy of the Star Wars universe created by George Lucas.
43 Megpoid Gumi
Megpoid is a Vocaloid by Internet Co., Ltd.. Her voice is sampled by Megumi Nakajima. The mascot of the software is called "Gumi". The name Gumi is the voice provider Megumi Nakajima's nickname from her childhood.
44 Strawberry Shortcake
Spyro is a series of platform games which primarily features the protagonist Spyro the Dragon and his friend, Sparx the Dragonfly.
46 Cooking Mama
She should stuff him in the oven. - Discord1
47 Judy Hopps
48 Nick Wilde
Yeah, use your phone to blind him!
49 Pizza Steve
Shrek is a character debuting in the 2001 animated movie of the same name. The popular franchise has 4 films and the character himself has become recognizable to people of all ages. He has since spawned into what is most likely the most widely recognized internet meme to ever come into the world.
The great ogre will kill Uncle Grandpa with the onions