1 Turanga Leela - Futurama
2 Fa Mulan - Mulan
3 Dot Warner - Animaniacs
Come she is a much better character than smurfette and sailor moon. She has a personality and she wasn't there just for sex appeal and she wasn't a girl stereotype.
She is a great cartoon character and Warner Brothers' first true original female character. - YakkoWakkoDot
4 Star Butterfly - Star vs. the Forces of Evil
Love Star! My No. 1 favorite cartoon character! - Sassy13crown
There's only one word to describe Star Butterfly and that is Awesome. - egnomac
5 Buttercup - The Powerpuff Girls
She is the one of the three main characters in the show The Powerpuff Girls. She was first created by Craig McCracken in 1992. She has short raven hair and green eyes with a green dress. She is known as the "toughest fighter" for her tomboyish attitude, being aggressive, and her love for fighting crime. ...read more.
6 Betty Boop - Betty Boop
Betty Boop is an animated cartoon character created by Max Fleischer, with help from animators including Grim Natwick.
7 Mandy - The Grim Adventures of Billy and Mandy
Amanda "Mandy" is a fictional character from the American animated series The Grim Adventures of Billy & Mandy created by Maxwell Atoms for Cartoon Network. She is perpetually a cynical, merciless girl from Endsville.
8 Misty - Pokemon
Misty, known as Kasumi in Japan, is a fictional character in the Pokémon franchise owned by Nintendo and created by Satoshi Tajiri. She’s the gym leader in Cerulean city & specializes in water Pokemon. In the games, she’s known as ‘the tomboy mermaid.’ ...read more.
9 Katara - Avatar: The Last Airbender
YASSS MY GIRL
10 Kim Possible - Kim Possible
? Meg Griffin - Family Guy
Megan "Meg" Griffin is a character from the animated television series Family Guy, voiced initially by Lacey Chabert, thereafter by Mila Kunis.
? Blossom - The Powerpuff Girls
Blossom is the leader of The Powerpuff Girls and one of the three main protaganists of the show. She was created in 1992 by Craig McCracken. She has long, red hair up in a ponytail with a giant red bow, pink eyes, pink dress with black belt, and white socks with Mary Jane shoes. She is intelligent, ...read more.
11 Rainbow Dash - My Little Pony: Friendship is Magic
Rainbow Dash is a female Pegasus pony from the popular 2010 kid's show My Little Pony: Friendship is Magic. She represents the element of loyalty is one of most well known characters of the show.
She may be a little mean sometimes but she still does what is best for her friends .
12 Louise Belcher - Bob's Burgers
13 Minnie Mouse - Mickey Mouse
Minerva "Minnie" Mouse is a funny animal cartoon character created by Ub Iwerks and Walt Disney. She was first drawn by Iwerks in 1928, as was Mickey Mouse.
14 Pinkie Pie - My Little Pony: Friendship is Magic
Pinkie Pie is a major character in the 2010 show My Little Pony: Friendship Is Magic, based on Surprise from My Little Pony G1, She represents the element of Laughter.
15 Marge Simpson - The Simpsons
Marjorie Jacqueline "Marge" Simpson is a fictional character in the American animated sitcom The Simpsons and part of the eponymous family.
16 Mabel Pines - Gravity Falls
Mabel Pines is one of the lead characters of the Disney XD animated series Gravity Falls. The character is voiced by Kristen Schaal, and designed by the series creator, Alex Hirsch. She is inspired by Hirsch's own twin sister, Ariel Hirsch. She is a caring, boy-crazy 12 year old girl that moved to the ...read more.
My name is Mable, it rhymes with "table"
17 Luna Loud - The Loud House
Luna Loud is the 3rd oldest sister, Luna's life forever changed following her first concert which started her passion and dream of being a rock star, Luna's personality can best be described as wild, caring and the loudest of the Louds like Leni she's very caring and enjoys being around the company ...read more.
18 Slappy Squirrel - Animaniacs
19 Rarity - My Little Pony: Friendship is Magic
Rarity is a female Unicorn pony from the 2010 Animated Television Series My Little Pony:Friendship is Magic. She is the element of Generosity and her main passion is fashion.
20 Princess Cadence - My Little Pony: Friendship Is Magic
21 Francine Smith - American Dad
22 Sandy Cheeks - Spongebob Squarepants
Sandra "Sandy" Cheeks is a fictional character in the Nickelodeon animated television series SpongeBob SquarePants.
23 Bubbles - The PowerPuff Girls
Bubbles is the deuteragonist in the animated television series The Powerpuff Girls, along with her sisters Blossom and Buttercup. She was created in 1992 by Craig McCraken for Cartoon Network's The Powerpuff Girls . She has blonde hair in two pigtails, blue eyes, blue dress with a black belt, and white ...read more.
She is the best and gloomiest girl ever
24 Lisa Simpson - The Simpsons
Lisa Marie Simpson is a fictional character in the animated television series The Simpsons. She is the middle child and most intelligent of the Simpson family.
25 Smurfette - The Smurfs
I love the Smurfs. She was one of my favorite characters. - Alpha101
26 April O'Neil - Teenage Mutant Ninja Turtles
April O'Neil is a fictional character from the Teenage Mutant Ninja Turtles comics. She is the first human ally of the Turtles: Leonardo, Donatello, Raphael, and Michelangelo.
27 Raven - Teen Titans
28 Coco - Foster's Home for Imaginary Friends
29 Princess Luna - My Little Pony: Friendship is Magic
30 Twilight Sparkle - My Little Pony: Friendship is Magic
Twilight Sparkle is the primary main character of My Little Pony Friendship is Magic. She is a female unicorn pony who transforms into an Alicorn and becomes a princess in Magical Mystery Cure.
31 Leni Loud - The Loud House
Leni Loud is a fictional character from The Loud House the second oldest of the Loud Family a bit of a ditz, forgetful and absent minded despite this she's a kindhearted person, a skilled fashion designer and is always willing to help others in need, she shares a room with Lori the oldest and suffers ...read more.
32 Sailor Moon (Serena) - Sailor Moon
33 Korra - The Legend of Korra
Avatar Korra is the title lead character in Nickelodeon's animated television series The Legend of Korra, in which she is depicted as the current incarnation of the Avatar, responsible for maintaining peace and balance in the world.
34 Wonder Woman - Justice League Unlimited
35 Supergirl - Justice League Unlimited
36 Lola Bunny - The Looney Tunes Show
Lola Bunny is a Looney Tunes cartoon character portrayed as an anthropomorphic female rabbit. She is Bugs Bunny's girlfriend. She was created as "female merchandising counterpart" to Bugs Bunny. She first appeared in the 1996 film Space Jam
37 Lynn Loud - The Loud House
At 13 years old, Lynn is the fifth-oldest child of the Loud family, and the youngest of Lincoln's five older sisters.
38 Babs Bunny - Tiny Toon Adventures
Despite being incredibly annoying at times she's actually pretty funny. - egnomac
39 Star Fire - Teen Titans
40 Marceline - Adventure Time
She's pretty great.
I hope we get to know more about her mother before the series ends.
41 Consuela - Family Guy
42 Daphne Blake - Be Cool, Scooby - Doo!
Daphne Ann Blake is a fictional character in the long-running American animated series Scooby-Doo. Daphne, depicted as coming from a wealthy family, is noted for her red hair, lavender heels, fashion sense, and her knack for getting into danger, hence the nickname "Danger Prone Daphne".
43 Lucy Loud - The Loud House
Lucy Loud is a fictional character in the Nickelodeon cartoon The Loud House. She was created by Chris Savino. Lucy is a goth and likes dark things.
44 Liane Cartman - South Park
45 Jessica Rabbit - Who Framed Roger Rabbit
Jessica Rabbit is a fictional character in Who Censored Roger Rabbit? and its loose film adaptation, Who Framed Roger Rabbit.
46 Belle - Beauty and the Beast
Belle is a fictional character who appears in Walt Disney Pictures' 30th animated feature film Beauty and the Beast (1991) and in the live action remake Beauty and the Beast (2017). Belle is the intelligent and selfless young daughter of an inventor who does not conform to the normal ways of her small ...read more.
She's a woman who's not looking for a prince who reads and is really intelligent. - egnomac
47 Ella - Total Drama
48 Lindsay - Total Drama
49 Gwen - Total Drama
50 Jazz Fenton - Danny Phantom
Jasmine "Jazz" Fenton is a fictional character and is the sister of Danny Phantom in the American animated series Danny Phantom created by Butch Hartman for Nickelodeon.