Top 10 Fictional Characters that Suffer from Crippling Depression

The Top Ten
1 GLaDOS - Portal GLaDOS is a fictional artificially intelligent computer system appearing in the video games Portal and Portal 2. The character was created by Erik Wolpaw and Kim Swift and voiced by Ellen McLain.
2 Squidward - Spongebob Squarepants Squidward Tentacles is a fictional character voiced by actor Rodger Bumpass in the American animated television series SpongeBob SquarePants.

More like anger issues...

3 Ren Hoek - Ren & Stimpy
4 Mr. Garrison - South Park Herbert Garrison is a recurring character in the American animated television series South Park. He is voiced by Trey Parker.
5 Alphys - Undertale Alphys is an adorably dorky, lab-coat-wearing, bespectacled, yellow-skinned lizard scientist who resides in her lab in Hotland in the critically acclaimed cult classic RPG known as Undertale, wherein she partakes in the daily act of watching insane amounts of anime and having a vast majority of the game's plot-related spoilers attached to her. Plot twists aside, however, she is also well known for creating the fabulous entertainment robot Mettaton, as well as having a massive crush on a young fish woman named Undyne, thus creating one of the most beloved lesbian couples in fiction.

She isn't depressed

6 Eeyore - Winnie the Pooh Eeyore is a character in the Winnie-the-Pooh books by A. A. Milne. He is generally characterized as a pessimistic, gloomy, depressed, anhedonic, old grey stuffed donkey who is a friend of the title character, Winnie-the-Pooh.

Very depressed

7 Lucas - Mother 3
8 Gollum - Lord of the Rings Gollum is a fictional character from J. R. R. Tolkien's legendarium. He was introduced in the 1937 children's fantasy novel The Hobbit, and became an important supporting character in its sequel, The Lord of the Rings. In Peter Jackson's Lord of the Rings and Hobbit trilogies, he is portrayed via motion capture by Andy Serkis.

Not depression, he suffers form schizophrenia.

9 Sadness - Inside Out Sadness is a major character in the 2015 Disney/Pixar film, Inside Out. She is one of the five emotions inside the mind of Riley Andersen.
10 Snape - Harry Potter
The Contenders
11 Fear - Inside Out

Actually, he suffers anxiety

12 Porky - Mother 3
13 Kenny - South Park
14 Orel - Moral Orel
15 Kif - Futurama
16 Marvin - The Hitchhiker's Guide to the Galaxy
17 Wayne - Hotel Transylvania
18 Negative Man - Mother 3
19 Cloud - Final Fantasy Cloud Strife, more commonly known as simply "Cloud", is a fictional video game character, the main protagonist of Square's video game Final Fantasy VII, which is a role playing game released in 1997. He also is the main protagonist of the high-definition version, as well as many of its sequels and spinoffs. ...read more.
20 Sephiroth - Final Fantasy VII Sephiroth is a fictional character and main antagonist in the role-playing video game Final Fantasy VII developed by Square.
21 Jules Winnfield - Pulp Fiction 17 speech. Jules' conversations and actions showcase the film's blend of dark humor and existential themes. His portrayal is considered one of Samuel L. Jackson's most iconic roles.
22 Samus - Metroid Samus Aran is the protagonist of the science fiction action-adventure game series Metroid by Nintendo. A galactic bounty hunter, Samus is usually equipped with her Power Suit, giving her access to weapons she uses to battle her enemies.
23 Eustace - Courage the Cowardly Dog Eustace Bagge is a fictional character from the Cartoon Network animated series, Courage the Cowardly Dog.
24 Mr. Freeze - Batman Mr. Freeze, real name Victor Fries, is a fictional supervillain appearing in American comic books published by DC Comics, commonly as an adversary of the superhero Batman.
25 Lammy - Um Jammer Lammy Um Jammer Lammy is a rhythm video game developed by NanaOn-Sha and published by Sony for the PlayStation video game console in 1999.
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