1 Deidara - Naruto Shippuden: Clash of Ninja 3
This boss is cheap. He keep teleporting and throw bombs at you 24/7. I rage quited for hours.
2 Death Egg Robot - Sonic the Hedgehog 2
You have no rings at all and you have to hit him about 16 or 18 times. It took me forever as a kid.
3 Vergil - Devil May Cry 3
4 Shadow Link - The Legend of Zelda 2: Link's Adventure
Go to the corner, crouch, then attack him while crouching. If not, then you will rage for a long time - Gehenna
But there is a good trick... A evil trick to deal with him.
5 Alien Wily - Mega Man 2
Bubbles... Bubbles beat him... At POINT BLANK RANGE!
6 King Koopa - Super Mario Bros. 3
7 Master Puppet - Naruto Uzuamaki Chronicles 2
I went out of control when I was a kid. He is that hard.
8 Perfect Cell - Dragon Ball Z Budokai
He is so fast and I have little health. Not fair game.
9 Super Man - Injustice: Gods Amoung Us
He is very very cheap on hard mode. You can barly get a scrach on him.
10 Shao Khan - Mortal Kombat 3
Yeah... I hate fighting shao khan.
The Contenders
11 Gwyn, Lord of Cinder - Dark Souls
12 Shake King - Wario Land: Shake It!
13 Super Dimentio - Super Paper Mario
14 King Boo - Luigi's Mansion
In the Super Mario series, King Boo is the leader of all the Boos and a major antagonist. He is an ally of King Bowser. He is depicted as a large white Boo with a crown similar to that of Princess Peach.
In the Luigi's Mansion series, King Boo serves as the main antagonist and Luigi's arch-nemesis. He is depicted as gargantuan, even larger than his Super Mario counterpart, with darker eyes, a purple tongue and pupils, and a golden crown with a corrupted power-enhancing jewel. He is considered to be one of the series' most evil villains.
15 Shadow Queen - Paper Mario: The Thousand Year Door
The Shadow Queen is the overarching antagonist and final boss of Paper Mario: The Thousand-Year Door. She is widely considered one of the most difficult bosses in the Paper Mario series.
16 Orochimaru - Naruto: Uzumaki Chronicles
Orochimaru is a fictional character from the Naruto universe created by Masashi Kishimoto and developed into a media franchise, which consists of a series of manga, anime, soundtracks, OVAs, movies, video games, and other collectibles.
17 The Machine - Henry Hatsworth in the Puzzling Adventure
18 Master Fortress - Super Smash Bros. 4
19 The Creators - F-Zero GX
20 Evil Twins - Crash Twinsanity
21 Admiral Razorbeard - Rayman 2: The Great Escape
22 Deus - Xenogears
23 Enigma - Puzzle & Dragons Z
An annoying boss from and awesome game
24 Zazel - Yo Kai Watch Blasters: Moon Rabbit Crew
As much as I love this game, I HATED the fight with Zazel, he attacks are strong and annoying, the most frustrating part is that his severts, Alicktokat and Duke Drooly also attack you too
25 Mr. Dark - Rayman