1 Lusamine - Pokemon
Lusamine is a fictional character introduced in Pokémon Sun and Moon. She is the head of the Aether Foundation.
She's so beautiful. But she's far frrom being a villain. She was misused. Her daughter and son saved her. And she turned a new leaf. - NaruHinaBlaze1
For someone who is over 40 years old, she sure has quite a young appearance! A beautiful one at that as well! - ModernSpongeBobSucks
Also, please don't judge me. I don't want to be taken as a disgusting pervert or whatever. - ModernSpongeBobSucks
How did I get here? - Not_A_Weeaboo
2 Irisviel von Einzbern - Fate/Zero
Irisviel von Einzbern is a fictional character from the Japanese visual novel and anime series Fate/stay night by Type-Moon and its prequel, Fate/Zero, by Type-Moon and nitroplus. She acts as the proxy master of Saber in Fate/Zero. She is the mother of Illyasviel von Einzbern and is married to Kiritsugu ...read more.
(When I say this, keep in mind that I am 100% straight) She's too adorable for that to me. - Elric-san
3 Ragyo Kiryuin - Kill la Kill
Ragyo Kiryuin is a fictional character in the anime television series Kill la Kill produced by Trigger. She is the mother of Satsuki Kiryuin and is the main antagonist of the series.
4 Masane Amaha - Witchblade
5 Sanae Furukawa - Clannad
6 Yasuko Takasu - Toradora
7 Yuriko Takagi - Highschool of the Dead
8 Haruka Ouma - Guilty Crown
9 Ageha Kurono - Rosario + Vampire
10 Michiko Malandro - Michiko & Hatchin
11 Helen Parr - The Incredibles
12 Lisa Lisa - JoJo's Bizarre Adventure
13 Virginia Wolfe - Rocko's Modern Life
She has undoubtedly THE sexiest brain I've ever written about - xandermartin98
14 Francine Smith - American Dad!
15 Lammy - Parappa the Rapper
Um Jammer Lammy is a rhythm video game developed by NanaOn-Sha and published by Sony for the PlayStation video game console in 1999.
She's played by Sara Ramirez and is a guitar-shredding redheaded tomboy, enough said - xandermartin98
16 Kushina Uzumaki - Naruto
Kushina Uzumaki is a fictional character from the manga and anime franchise Naruto, created by Masashi Kishimoto.
17 Lois Griffin - Family Guy
Lois Patrice Griffin is one of the main characters of the American animated television series Family Guy.
18 Maddie Fenton - Danny Phantom
Madeline "Maddie" Fenton is a fictional character and is the mother of Danny Phantom in the American animated series Danny Phantom created by Butch Hartman for Nickelodeon.
She is one of the SEXIEST animated babes ever. I wish we could se her in a BIKINI!
19 Debbie Turnbull - Robotboy
20 Gloria Pritchett - Modern Family
She's played by Sofia Vergara. Enough said.
21 Marge Simpson - Simpsons
Marjorie Jacqueline "Marge" Simpson is a fictional character in the American animated sitcom The Simpsons and part of the eponymous family.
22 Nozomi Tojo (Toujou) - Love Live School Idol Project
I think she counts as a MILF because she and Eli act like a mother and a father to the other Muse members. - PerfectImpulseX
23 Dexter's Mom - Dexter's Laboratory
24 Drew Saturday - The Secret Saturdays
25 Donna Tubbs-Brown - The Cleveland Show
26 Gladys - The Grim Adventures of Billy & Mandy
27 Claire - The Grim Adventures of Billy & Mandy
28 Mrs. Turner - The Fairly OddParents
29 Betty Rubble - The Flintsones
30 Bonnie Swanson - Family Guy
Bonnie is more prettier than Lois and Francine. 😍
31 Toriel - Undertale
Toriel is a main character in Toby Fox's 2016 RPG, Undertale. She is an amazing blend of goat and mother.
32 Vanilla the Rabbit - Sonic
33 Dr. Hutchison - Rocko's Modern Life
34 Roz - Monster Inc
Roz is a slug-style monster in Monsters, Inc. who appears to be the key master and administrator for Scare Floor F, holding all the keys to children's closet doors at Monsters, Inc.
35 Nanoha Takamachi - Magical Girl Lyrical Nanoha
36 Fate Testarossa - Magical Girl Lyrical Nanoha
37 Signum - Magical Girl Lyrical Nanoha
38 Tsunade Senju - Naruto
39 Moxy - UglyDolls
40 Tsunade - Naruto
Tsunade is a fictional character from the manga and anime franchise Naruto, created by Masashi Kishimoto.