Top Ten Best Items In The Binding of Isaac: Rebirth

Easily the best. Amazing synergies, excels at clearing rooms and destroying bosses, and has unlimited range.

The damage to every enemy is crazy

A single damage up with this item allows for rapid destruction when using it as melee.

Hard to unlock but is worth it

Not anymore it isn't.

Great to get at the start of a game

The increased chance of devil rooms is great