1 South Park
South Park is an American adult animated sitcom created by Trey Parker and Matt Stone for the Comedy Central television network. The show is about four boys, who are Stan Marsh, Kyle Broflovski, Eric Cartman, and Kenny McCormick, and their adventures in South Park, Colorado.
2 Family Guy
Family Guy is an American adult animated sitcom created by Seth MacFarlane for the Fox Broadcasting Company. The series centers on the Griffins, a family consisting of parents Peter (Idiotic Dad) and Lois (Nagging Wife), their children Meg (Socially Awkward Daughter) Chris (Idiotic Son), and Stewie ...read more.
How is this not number one? It's the most racist cartoon still running!
Seth McFarlane should just admit he hates Jews. I don't give a crap he has some Jewish background. He's as Jewish as a pulled pork sandwich! F- him
CatDog is an American animated television series created by Peter Hannan for Nickelodeon. The series depicts the life of conjoined brothers, with one half being a cat and the other a dog.
Seasons 1-3 were fine, but season 4 was insanely mean-spirited. - RalphBob
I always felt sorry for Cat.
4 Foster's Home for Imaginary Friends
Foster's Home for Imaginary Friends is an American animated television series created by Craig McCracken for Cartoon Network Studios.
5 Looney Tunes
Looney Tunes is an American animated series of comedy short films produced by Warner Bros. from 1930 to 1969 during the golden age of American animation, alongside its sister series Merrie Melodies.
How is this mean spirited? - RalphBob
6 Ren and Stimpy
The Ren & Stimpy Show, often simply referred to as Ren & Stimpy, is an American animated television series created by John Kricfalusi for Nickelodeon.
7 Sanjay and Craig
Sanjay and Craig is an American animated television series produced by Nickelodeon. The show is about a 12-year-old boy named Sanjay Patel who owns a talking pet snake named Craig. It ran from May 25th, 2013 to
July 29th, 2016.
Breadwinners is a 2014 animated comedy television series produced by Nickelodeon. It is about the adventures of SwaySway and Buhdeuce, two ducks who drive in a rocket van delivering bread to their customers.
9 Ed, Edd n Eddy
Ed, Edd n Eddy is a Canadian-American animated comedy television series created by Danny Antonucci for Cartoon Network, and the sixth of the network's Cartoon Cartoons. The series revolves around three preteen boys: Ed, Edd "Double D," and Eddy—collectively known as "the Eds"—who live in a suburban ...read more.
10 The Fairly OddParents
The Fairly OddParents is an American animated television series created by Butch Hartman for Nickelodeon.
? Trolls: The Beat Goes On!
This should be number one! It’s a lot more mean spirited than those other cartoons!
11 Scaredy Squirrel
You ain't kidding, one of the biggest main characters is tortured and beaten up constantly!
13 Rabbids Invasion
Rabbids Invasion (French: Les Lapins Crétins : Invasion) is a French/American animated television series which premiered on August 3, 2013, on Nickelodeon. The series began airing on Nicktoons during its second season in late 2015. On June 23, 2017, the series finale ended during its third season. ...read more.
14 Bob's Burgers
Bob's Burgers is an American animated sitcom created by Loren Bouchard for The Fox Broadcasting Company. It premiered on January 9, 2011 and is still running as of 2017.
15 Gravity Falls
Gravity Falls is an American animated television series produced by Disney Television Animation that first aired on Disney Channel, and then on Disney XD from June 15, 2012 to February 15, 2016. The series follows the adventures of Dipper Pines and his twin sister Mabel in the fictional town of Gravity ...read more.
16 The Simpsons
The Simpsons is an American animated sitcom created by Matt Groening that originally started on April 19, 1987 as shorts on The Tracey Ullman Show. It got its own series on December 17, 1989 and is still running as of 2018, making it the longest running animated sitcom. It is about a man named Homer ...read more.
Braceface is a Canadian/American animated series that aired on Teletoon in Canada, and on Disney Channel and ABC Family in the United States, as well as Fox Kids and then Pop Girl in the United Kingdom.
Feel bad for Sharon having to deal with her problems
18 Harvey Beaks
Harvey Beaks is an American animated television series created by C.H. Greenblatt for Nickelodeon. Originally announced to premiere on March 29, 2015, the series instead premiered on March 28, 2015 following the 2015 Kids' Choice Awards.
19 Mickey Mouse Cartoons
20 Kid vs. Kat
Kid vs. Kat is a Canadian animated television series developed and produced at Studio B Productions, in association with YTV and Jetix Europe for its first season and Disney XD Europe for its second season.
The entire show is just the two characters trying to murder each other.
21 Invader ZIM
Invader Zim is an American animated television series created by Jhonen Vasquez for Nickelodeon. The series centers on an extraterrestrial named Zim from the planet Irk, and his mission to conquer Earth and enslave the human race along with his malfunctioning robot servant GIR.
22 Chip n' Dale's Rescue Rangers
Mean spirited at times... but still a great show.
23 Robot and Monster
Especially if you count Gart
24 Teen Titans Go!
'Teen Titans Go!' is an American animated television series produced by Cartoon Network. The show follows a superhero group called the Teen Titans, and shows what happens when they go home and have silly adventures. This show is Cartoon Network's revival of the popular 2003-2006 American animated television ...read more.
25 The Boondocks
Cantankerous Robert "Granddad" Freeman is the legal guardian of his grandsons, 10-year-old revolutionary Huey and 8-year-old Riley, a product of contemporary rap culture. After moving the family from Chicago's South Side to the safety of suburban Woodcrest -- aka the boondocks -- Granddad hopes to ignore ...read more.
26 SpongeBob SquarePants
SpongeBob SquarePants is an American animated television series created by marine biologist and animator Stephen Hillenburg for Nickelodeon. SpongeBob is currently the most popular show on Nickelodeon, as well as the longest running show, running for 18 years, and is beginning its 11th season. The show ...read more.
27 Tom and Jerry
Tom and Jerry is an American animated series of short films created in 1940, by William Hanna and Joseph Barbera.
29 The Lion Guard
The Lion Guard is an American animated television series developed by Ford Riley based on Disney's 1994 film The Lion King. The series was first broadcast with a television movie titled The Lion Guard: Return of the Roar on Disney Channel on November 22, 2015 and began airing as a TV series on January ...read more.
30 The Brothers Flub
31 The Amoeba Sisters
32 Drawn Together
Drawn Together is an American adult animated sitcom which ran on Comedy Central from October 27, 2004 to November 14, 2007. The series was created by Dave Jeser and Matt Silverstein, and uses a sitcom format with a TV reality show setting.
33 Making Fiends
Making Fiends is an American comedy horror animated television series. Based upon a web series with the same name, the series ran from October 4, 2008 to November 1, 2008 on Nicktoons Network.
34 Dexter's Laboratory
Dexter's Laboratory is an American comic science fiction animated television series created by Genndy Tartakovsky for Cartoon Network, and the first of the network's Cartoon Cartoons. The show is about a kid scientist named Dexter that has a sister named Dee Dee that keeps breaking into his lab.
35 The Grim Adventures of Billy & Mandy
The Grim Adventures of Billy & Mandy (also known as Billy & Mandy) is an American animated television series created by Maxwell Atoms for Cartoon Network, and is the 14th of the network's Cartoon Cartoons (albeit namely when it was part of Grim & Evil; the show is considered separate from Cartoon Cartoons ...read more.
Recess is an American animated television series created by Paul Germain and Joe Ansolabehere and produced by Walt Disney Television Animation, with animation done by Grimsaem, Plus One Animation, Sunwoo Animation, and Toon City.
37 My Gym Partner's a Monkey
My Gym Partner's a Monkey is an American animated television series that was created by Tim Cahill and Julie McNally Cahill and produced by Cartoon Network Studios.
I really wish that this show wasn't mean spirited at all!
I'm guessing it's because Adam is treated poorly for being a human - VeranAsh
W.I.T.C.H. is a French-Italian-American animated television series based on the Italian comic book series of the same name.
39 Mr. Pickles
Mr. Pickles is an American animated television series created by Will Carsola and Dave Stewart for Adult Swim. The series revolves around the Goodman family, especially their 6-year-old son named Tommy and the family's border collie, the demonic Mr. Pickles. The series was picked up for 10 quarter-hour ...read more.
40 My Little Pony: Friendship is Magic
My Little Pony: Friendship Is Magic is a children's animated fantasy television series developed by Lauren Faust, produced by Hasbro Studios and DHX Media Vancouver . Despite the target demographic of young girls, Friendship Is Magic has also gained a large following of older viewers, mainly young and ...read more.