1 Family Guy
Family Guy is an American adult animated sitcom created by Seth MacFarlane for the Fox Broadcasting Company. The series centers on the Griffins, a family consisting of parents Peter (Fat, Idiotic Dad) and Lois (Nagging Bitchy Wife), their children Meg (Socially Awkward Daughter) Chris (Fat, Idiotic ...read more.
How is this less mean-spirited than Grojband? At least Grojband doesn't have domestic violence and child abuse!
Seth McFarlane should just admit he hates Jews. I don't give a crap he has some Jewish background. He's as Jewish as a pulled pork sandwich! F- him
This show should be number one. Most mean spirited show I have ever seen.
How is this not number one? It's the most racist cartoon still running!
2 South Park
South Park is an American adult animated sitcom created by Trey Parker and Matt Stone for the Comedy Central television network. The show is about four boys, who are Stan Marsh, Kyle Broflovski, Eric Cartman, and Kenny McCormick, and their adventures in South Park, Colorado.
CatDog is an American animated television series created by Peter Hannan for Nickelodeon. The series depicts the life of conjoined brothers, with one half being a cat and the other a dog.
Seasons 1-3 were fine, but season 4 was insanely mean-spirited. - RalphBob
I always felt sorry for Cat.
Leave CatDog alone, Rancid Rabbit! - IceBearRules
At the very least, both Cat and Dog deserved it at points. Still a very good show. - KalloFox34
4 Looney Tunes
Looney Tunes is an American animated series of comedy short films produced by Warner Bros. from 1930 to 1969 during the golden age of American animation, alongside its sister series Merrie Melodies.
How is this mean spirited? - RalphBob
How is the mean spirited, Doc? - kcianciulli
5 Ed, Edd n Eddy
Ed, Edd n Eddy is a Canadian-American animated comedy television series created by Danny Antonucci for Cartoon Network, and the sixth of the network's Cartoon Cartoons. The series revolves around three preteen boys: Ed, Edd "Double D," and Eddy—collectively known as "the Eds"—who live in a suburban ...read more.
Oh, and the most frequent targets of this (Ed and Edd) usually did nothing to deserve the abuse they get. Eddy's more of a jerk, but considering hellish characters like Kevin and ESPECIALLY Sarah, can you blame this guy? I hate this show a lot. - KalloFox34
This is got to be an annoying theme song. - ajacraig2011
6 Foster's Home for Imaginary Friends
Foster's Home for Imaginary Friends is an American animated television series created by Craig McCracken for Cartoon Network Studios.
7 Sanjay and Craig
Sanjay and Craig is an American animated comedy television series that aired on Nickelodeon from May 25, 2013, to July 29, 2016, for three seasons and 60 episodes. The series is about a 12-year-old boy named Sanjay Patel who owns a talking pet snake named Craig.
8 Ren and Stimpy
The Ren & Stimpy Show, often simply referred to as Ren & Stimpy, is an American animated television series created by John Kricfalusi for Nickelodeon.
9 Ren & Stimpy "Adult Party Cartoon"
Ren evolved into a completely irredeemable, abusive bastard in this show. - KalloFox34
Ren Seeks Help, enough said. - Catacorn
Curse you, APC Ren! - IceBearRules
Breadwinners is a 2014 animated comedy television series produced by Nickelodeon. It is about the adventures of SwaySway and Buhdeuce, two ducks who drive in a rocket van delivering bread to their customers.
Superjail! is an American animated television series produced by Augenblick Studios in its first season, and by Titmouse, Inc. in its second, third, and fourth seasons. A fourth season was confirmed on the Twitter page of David Wain, who voices the character of the Warden. The series follows the events ...read more.
12 The Fairly OddParents
The Fairly OddParents is an American animated television series created by Butch Hartman for Nickelodeon.
Grojband is a Canadian animated series developed by Fresh TV and distributed by FremantleMedia, Ltd and created by Todd Kauffman and Mark Thornton. ...read more.
Ed Edd n Eddy can be described as mean-spirited but nobody complains about that. Don't get me wrong, I still love Ed Edd n Eddy but it's way more mean-spirited than Grojband could ever hope to be. At least in Grojband the mean characters get karma and the nice ones come out on top. In Ed Edd n Eddy, the torment almost always goes back to the Eds, even when they don't do anything wrong. - regularponyfan09
I LIKE THAT SHOW WHY
14 Scaredy Squirrel
You ain't kidding, one of the biggest main characters is tortured and beaten up constantly!
16 SpongeBob SquarePants
SpongeBob SquarePants is an American animated television series created by marine biologist and animator the late Stephen Hillenburg for Nickelodeon. SpongeBob is currently the most popular show on Nickelodeon, as well as the longest running show, running for 20 years, and is beginning its 12th season. ...read more.
Post-Movie yes, Pre-Movie no. How are episodes like Band Geeks and Chocolate With Nuts mean? And how is this worse than Mr. Pickles, Pre-Movie SB is one of the best cartoons in cartoon history, how on earth is Mr. Pickles worse, have you ever seen Band Geeks. Plus even the seasonal rot isn't as mean spirited as Mr. Pickles is.
Squidward torture and characters not getting karma after they did something bad (especially Mr. Krabs), this show is so bad in many different levels and out of character.
17 Rabbids Invasion
Rabbids Invasion (French: Les Lapins Crétins : Invasion) is a French/American animated television series which premiered on August 3, 2013, on Nickelodeon. The series began airing on Nicktoons during its second season in late 2015. On June 23, 2017, the series finale ended during its third season. ...read more.
18 Bob's Burgers
Bob's Burgers is an American animated sitcom created by Loren Bouchard for The Fox Broadcasting Company. It premiered on January 9, 2011 and is still running as of 2017.
19 Gravity Falls
Gravity Falls is an American animated television series produced by Disney Television Animation that first aired on Disney Channel, and then on Disney XD from June 15, 2012 to February 15, 2016. The series follows the adventures of Dipper Pines and his twin sister Mabel in the fictional town of Gravity ...read more.
20 The Simpsons
The Simpsons is an American animated sitcom created by Matt Groening that originally started on April 19, 1987 as shorts on The Tracey Ullman Show. It got its own series on December 17, 1989 and is still running as of 2019, making it the longest running animated sitcom. It is about a man named Homer ...read more.
This show has gotten more cruel lately. One episode has Bart attenpt suicide because everyone is relentlessly bullying him for losing a baseball game. Another has Bart shamelessly exploiting Principal Skinner's peanut allergy. And yet another one has everyone hate the whole family after Bart accidentally moons the flag (long story). - KalloFox34
21 Mr. Pickles
Mr. Pickles is an American animated television series created by Will Carsola and Dave Stewart for Adult Swim. The series revolves around the Goodman family, especially their 6-year-old son named Tommy and the family's border collie, the demonic Mr. Pickles. The series was picked up for 10 quarter-hour ...read more.
Braceface is a Canadian/American animated series that aired on Teletoon in Canada, and on Disney Channel and ABC Family in the United States, as well as Fox Kids and then Pop Girl in the United Kingdom.
Feel bad for Sharon having to deal with her problems
23 Harvey Beaks
Harvey Beaks is an American animated television series created by C.H. Greenblatt for Nickelodeon. Originally announced to premiere on March 29, 2015, the series instead premiered on March 28, 2015 following the 2015 Kids' Choice Awards.
24 Mickey Mouse Cartoons
25 Kid vs. Kat
Kid vs. Kat is a Canadian animated television series developed and produced at Studio B Productions, in association with YTV and Jetix Europe for its first season and Disney XD Europe for its second season.
The entire show is just the two characters trying to murder each other.