Top 10 Best Parodies in Fiction

The Top Ten
1 Courage the Cowardly Dog (a parody of Scooby-Doo and Looney Tunes) from the Cartoon Cartoons franchise Courage the Cowardly Dog is an American animated horror comedy television series created by John R. Dilworth for Cartoon Network as part of the network's Cartoon Cartoons block.
2 Kabbage Boy (a parody of the incredibly whiny and lame posers that Heavy Metal fans often see Nu Metal band members as) from Brutal Legend

"I can fix anything...except THAT." - Eddie Riggs talking about this band and its music

3 Mr. Garrison (a parody of the excessively numerous racist Republican rednecks that live in the United States) from South Park Herbert Garrison is a recurring character in the American animated television series South Park. He is voiced by Trey Parker.

He even is homophobic despite being the show's most LGBT character

4 Luigi's Mansion (a parody of Resident Evil 1) from the Super Mario franchise

It has RE 1's creepy mansion, RE 1's campiness and even RE 1's door-opening cutscenes

5 Boyd Cooper (a parody of weird and insane conspiracy theorists) from Psychonauts
6 Mermaid Man (a parody of Aquaman) from Spongebob Squarepants Mermaid Man is a fictional character in the Nickelodeon animated television series SpongeBob SquarePants. He was voiced by Ernest Borgnine from 1999 to his death in 2012.

He is so hilariously pathetic that he actually makes Aquaman look amazing

7 Dan Hibiki (a parody of Street Fighter's excessively numerous Shoto Clones and SNK's knock-offs of them) from Street Fighter

He is "bottom tier" but is so egotistical that he calls himself "top tier"

8 Wacky Delly (a parody of Nickelodeon's painfully mediocre taste in shows) from Rocko's Modern Life

It even foreshadows Spongebob's existence with Mr. Cheese and Sal Ami
(Mr. Cheese looks like a triangular version of Spongebob,
while Sal Ami basically acts like Patrick)

9 Mario's Mystery Meat (a parody of Vinesauce) from Super Mario World
10 Di Lung (a parody of Rich Asian Douchebags) from Courage the Cowardly Dog
The Contenders
11 South Park (a parody of politics and pop culture) South Park is an American adult animated sitcom created by Trey Parker and Matt Stone for the Comedy Central television network. The show is about four boys, who are Stan Marsh, Kyle Broflovski, Eric Cartman, and Kenny McCormick, and their adventures in South Park, Colorado.
12 Francis (a parody of the fan bases of anime shows and video games) from Super Paper Mario

He really does LOVE complaining about video games that he has never played on message boards

13 Austin Powers (a parody of James Bond) Sir Augustine Danger "Austin" Powers is a fictional character from the Austin Powers series of films, and is created and portrayed by Mike Myers.
14 Medaka Box (a parody of high school anime)
15 Tengen Toppa Gurren Lagann (a parody of mecha anime) Gurren Lagann, known in Japan as Tengen Toppa Gurren Lagann, is an anime series animated by Gainax and co-produced by Aniplex and Konami. It was also directed by Hiroyuki Imaishi and written by veteran playwright Kazuki Nakashima.
16 Kung Fu Hustle (a parody of martial arts movies)
17 Mobile Fighter G Gundam (a parody of martial arts movies and mecha anime)
18 Symphogear (a parody of military moe anime, magical girl anime, and idol anime)
19 Johnny Bravo (a parody of "chads") from Johnny Bravo
20 Deadpool (a parody of superhero movies)
21 Shrek (a parody of fairy tales)
22 Laura Bodewig (a parody of Asuka Langley Sohryu) from Infinite Stratos
23 Ren (a parody of Peter Lorre) from Ren & Stimpy
24 Panty & Stocking with Garterbelt (a parody of what Japanese people and American people see each other's versions of cartoons as)
25 Dandy (a parody of "chads") from Space Dandy
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