Best TV Shows With Two or More Main Protagonists

OK, shows can have multiple main characters, but for this list I'm specifically talking about ones where there are two or more main protagonists. Like for example, SpongeBob has multiple main characters, but the true protagonists is SpongeBob himself. Compare that to shows like Tom and Jerry or Drake & Josh where there are two true protagonists and you'll see. EVER!
The Top Ten
1 Adventure Time Adventure Time is an American animated television series created by Pendleton Ward for Cartoon Network. The series follows the adventures of a boy named Finn (voiced by Jeremy Shada) and his best friend and adoptive brother Jake (voiced by John DiMaggio)—a dog with the magical power to change shape and size at will. Finn and Jake live in the post-apocalyptic Land of Ooo. Throughout the show, they interact with the other main characters Princess Bubblegum (voiced by Hynden Walch), the Ice King (voiced by Tom Kenny), and Marceline the Vampire Queen (voiced by Olivia Olson). The series is based on a short produced for Nicktoons and Frederator Studios' animation incubator series Random! Cartoons. ...read more.

Focuses largely on both Finn and Jake.

Love finn and jake very good people

2 Steven Universe Steven Universe is an American animated television series created by Rebecca Sugar for Cartoon Network. The show's based around a young boy by the name of Steven Universe, who is a hybrid of a gem and a human. He lives with his gem friends, Garnet, Amethyst and Pearl.
3 Totally Spies! Totally Spies! is a French-Canadian animated spy comedy television series created by Vincent Chalvon-Demersay and David Michel and produced by Marathon Media Group and Image Entertainment Corporation.
4 Tom and Jerry Tom and Jerry is an American animated series of comedy short films created in 1940 by William Hanna and Joseph Barbera. Best known for its 161 theatrical short films by Metro-Goldwyn-Mayer, the series centers on a rivalry between the title characters Tom, a cat, and Jerry, a mouse. Many shorts also feature several recurring characters.

They're bitter rivals, but still both protagonists. You can't have one without the other.

This show is a classic!

5 Winx Club Winx Club is an Italian animated television series directed, created and produced by Iginio Straffi and his company Rainbow S.r.l.

Best show I've ever seen! Sailor Moon is the best too, and sometimes it's hard to choose which is bettter! Also, there are 5 main characters: Bloom, Stella, Flora, Musa, and Aisha. My favorite is either Stella or Flora.

6 Teen Titans Teen Titans is an American animated television series created by Glen Murakami, based on the DC Comics characters of the same name.

Not teen titans go! that show is crap but this show yes just yes

7 Regular Show Regular Show is an American animated television series created by J. G. Quintel for Cartoon Network that premiered on September 6, 2010. The series revolves around the lives of two friends, a blue jay named Mordecai and a raccoon named Rigby—both employed as groundskeepers at a local park.

It's hard to define which of the two is the "main" protagonist.

8 Liv and Maddie Liv and Maddie is a live-action Disney Channel sitcom that started on July 19, 2013, and ended on March 24, 2017. It is about two identical twin sisters named Olivia "Liv" Rooney and Madison "Maddie" Rooney (both portrayed by actress Dove Olivia Cameron; born in January 1996 as Chloe Celeste Hosterman) who reunite after one of them, Liv, returns to her home to see her family after four years of starring on a hit musical sitcom entitled "Sing It Loud!". The show is both a comedy and a drama, and is intended for viewers of all ages. In total it has had four complete seasons and its fourth and final season started on September 23, 2016.

Liv is just as important to the plot as Maddie is. I love how they're best friends despite being completely different! That's why it's like The Fox and the Hound!

9 Teletubbies Teletubbies is a British pre-school children's television series created by Ragdoll Productions' Anne Wood CBE and Andrew Davenport, who wrote each of the show's 365 episodes. It is owned by Canadian Studio WildBrain, which is the largest independent Children's and Adolescent's Film Studio

That sun with the baby face still freaks me out

Of the four Teletubbies, Po is my favorite of them by far. Go, Po, go!

10 The Amazing World of Gumball The Amazing World of Gumball is a British-Australian-German-American-Irish children's animated television series created by Ben Bocquelet for Cartoon Network.

Great show

love the fact that gumball and darwin depend on each other but their not brothers

Gumball and Darwin

The Contenders
11 We Bare Bears An animated comedy show by Daniel Chong about three different species of bears - Grizzly, Panda and Ice bear (polar bear). Since they were little, they wanted to get adopted by owners separately. But then they missed each other too much, so they reunited again. Now as adults, they now live in a cave ...read more.
12 Best Friends Whenever Best Friends Whenever is an American multi-camera sitcom developed for Disney Channel, created by Jed Elinoff and Scott Thomas and executive produced by Jed Elinoff, Scott Thomas, and Michael B. Kaplan. The series stars Landry Bender as Cyd, Lauren Taylor as Shelby, Gus Kamp as Barry, Ricky Garcia as Naldo, Benjamin Cole Royer as Bret, and Matthew Lewis Royer as Chet. The series premiered on June 26, 2015.

I like the fact that Cyd and Shelby can time travel. It's very interesting!

13 Full House Full House is an American sitcom created by Jeff Franklin for ABC. The show chronicles a widowed father, Danny Tanner, who enlists his best friend and brother-in-law to help raise his three daughters.

All the family are the protagonists.

14 Rugrats Rugrats is an American animated television series created by Arlene Klasky, Gábor Csupó and Paul Germain for Nickelodeon.

Similar to Teletubbies, there are four protagonists who are all babies. The difference? They aren't aliens.

"A baby's gotta do what a baby's gotta do! " -Tommy Pickles

15 Gravity Falls Gravity Falls is an American animated television series produced by Disney Television Animation that first aired on Disney Channel, and then on Disney XD from June 15, 2012 to February 15, 2016. The series follows the adventures of Dipper Pines and his twin sister Mabel in the fictional town of Gravity ...read more.
16 Phineas and Ferb Phineas and Ferb is an American animated comedy-musical television series. Originally broadcast as a one-episode preview on August 17, 2007 and again previewed on September 28, 2007, the series officially premiered on February 1, 2008 and ended on June 12, 2015 on Disney Channel, and follows Phineas Flynn and his British stepbrother Ferb Fletcher on summer vacation.

Another buddy show.

17 Looney Tunes Looney Tunes is an American animated series of comedy short films produced by Warner Bros. from 1930 to 1969 during the golden age of American animation, alongside its sister series Merrie Melodies.

Like Tom and Jerry, it's a classic show from the good old days.

18 Drake & Josh Drake & Josh is an American television sitcom created by Dan Schneider for Nickelodeon. The series follows the lives of two teenage boys with opposite personalities, Drake Parker (Drake Bell) and Josh Nichols (Josh Peck), who become stepbrothers. Both actors previously appeared in The Amanda Show along with Nancy Sullivan, who plays Drake and Megan's mother in the series. Miranda Cosgrove plays Megan, Drake's mischievous younger sister, and Jonathan Goldstein plays Walter, Josh's father. The series' opening theme song, "Found a Way", is written by Drake Bell and Backhouse Mike and performed by Bell. The series ran from January 11, 2004, to September 16, 2007, totaling 57 episodes in 4 seasons. ...read more.

Even if you hate this show or any other Disney or Nick show on this list, you at LEAST have to admit: they are FAR better than the crap currently on Disney and Nick now.

I miss this show hey anyone remember the one when they made a sitcom about drake and josh in drake and josh lol

This is the best nick sitcom ever! No modern nick show can beat it!

I love this sitcom!

19 Family Guy Family Guy is an American adult animated sitcom created by Seth MacFarlane for the Fox Broadcasting Company. The series centers on the Griffins, a family consisting of parents Peter (Fat, Idiotic Dad) and Lois (Nagging Bitchy Wife), their children Meg (Socially Awkward Daughter) Chris (Fat, Idiotic ...read more.
20 The Grim Adventures of Billy & Mandy The Grim Adventures of Billy & Mandy (also known as Billy & Mandy) is an American animated television series created by Maxwell Atoms for Cartoon Network, and is the 14th of the network's Cartoon Cartoons (albeit namely when it was part of Grim & Evil; the show is considered separate from Cartoon Cartoons ...read more.
21 Catscratch Catscratch is an American animated television series created by Doug TenNapel (also known for creating Earthworm Jim). It was aired on both Nickelodeon and Nicktoons on July 9, 2005 and ended February 10, 2007. It is an adaptation of TenNapel's graphic novel, Gear, which is also the name of the cats' monster truck. The series features music composed by longtime TenNapel collaborator, Terry Scott Taylor. Catscratch's first DVD appearance was on Nick Picks Vol. 3, which came out on February 7, 2006 (though the DVD contained only "Bringin' Down the Mouse").

I miss this show. I don't understand why it only got one season when shows like The Mighty B!, Breadwinners, Rabbids Invasion, Sanjay and Craig, and Fanboy and Chum Chum were given at least two or three seasons.

22 Friends Friends is an American television sitcom, created by David Crane and Marta Kauffman, which originally aired on NBC from September 22, 1994, to May 6, 2004, lasting ten seasons. It now airs on Nick at Nite. The story is primarily about 6 individuals (Ross [David Schwimmer], and his sister, Monica [Courtney Cox], Joey and Chandler [Matt LeBlanc and Matt Perry], who are best friends, Jennifer [Rachel Green], and Phoebe [Lisa Kudrow]. The characters constantly get into situations and love affairs and such in the plot.

All 6 friends are main characters

23 That '70s Show That '70s Show is an American television period sitcom that originally aired on Fox from August 23, 1998, to May 18, 2006. The series focused on the lives of a group of teenage friends living in the fictional suburban town of Point Place, Wisconsin, from May 17, 1976, to December 31, 1979.
24 Dragon Ball Z Dragon Ball Z is a Japanese anime television series produced by Toei Animation. Dragon Ball Z follows the adventures of Goku who, along with the Z Warriors, defends the Earth against evil. The action adventures are entertaining and reinforce the concept of good versus evil. Dragon Ball Z teaches valuable ...read more.
25 The Simpsons The Simpsons is an American animated sitcom created by Matt Groening that originally started on April 19, 1987 as shorts on The Tracey Ullman Show. It got its own series on December 17, 1989 and is still running as of 2023, making it the longest running animated sitcom. It is about a man named Homer Simpson and his family (wife Marge and children Bart, Lisa and Maggie and pets, Snowball II and Santa's Little Helper) going through a long series of misadventures.
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