Top 10 Most Hallucinogenic Drugs

1. DMT

   DMT, or N,N-Dimethyltryptamine, is a naturally occurring psychedelic compound found in various plants and animals. It is known for producing intense, short-acting visual and auditory hallucinations when inhaled or smoked. The compound is structurally related to serotonin and acts primarily on serotonin receptors in the brain.

   DMT is a very interesting drug. It might not be for everyone, but if you like psychedelics, then you must try this. People talk about breaking through. I've smoked it about 8 times and never broke through. Amazing experience, but I was still in the real world, just with out-of-this-world visuals. The colors in stuff are intensified tenfold. You can't believe your brain is seeing what it's seeing.

   I then had it in a capsule at a party, which was also a very nice experience, similar to having a strong LSD, only it lasted about 5 to 6 hours, unlike tabs which can last up to 12. But when I took a capsule another time, I think I was breaking through. I kept coming in and out of reality and was getting overwhelmed by my own thoughts. Going into a dream world I was making up in my thoughts. This wasn't like me. I felt like breaking through was for people who dreamed a lot or for weak-minded people that couldn't handle drugs, as I've had loads of psychedelics in my life and never left reality. This time, I did, and I was re-enacting thoughts. I was having a dream, I think. I don't know. Very out of character for me. I don't dream.

   It's a good idea to know how much DMT is in the capsule you're having because a big hit can break you through, as they say. I wasn't in control and kept coming and going out of reality. I'd be fine one minute talking to my girlfriend for a good ten to fifteen minutes, then I would just go again into another reality and not talk, but I thought I was. Really strange. The drug itself is amazing. Just don't take too much, especially if consuming in capsule form, as the effects last longer.

2. Magic Mushrooms

   Magic mushrooms refer to fungi that contain the hallucinogenic compounds psilocybin and psilocin. These substances induce altered states of consciousness, often involving visual distortions and changes in perception. Psilocybin is metabolized into psilocin, which interacts with serotonin receptors in the brain.

   The first time I did it, it was carelessly just trying to have fun, and it changed my life. When you hallucinate and get worried, stop worrying, breathe, and let the trip happen. The more you go against the trip, the more likely you are to have paranoia, and that leads to a bad trip. But if you are prepared mentally, it can be amazing and it makes you look at the world from a whole new perspective.

   When I had a good trip, it was amazing. Everything in your sight is vivid, and it's something you should do at least once in your life if you're up for it. And even if you do have a bad trip, it's okay. Bad trips are very beneficial, and they can help you work towards fixing your flaws. If you're going to take them for the first time, take no more than 1.5 grams.

3. Ayahuasca

   Ayahuasca is a traditional South American brew made from Banisteriopsis caapi and plants containing DMT. The monoamine oxidase inhibitors (MAOIs) in the vine allow orally consumed DMT to become active. It is commonly used in ceremonial contexts and can induce vivid visions and emotional experiences.

   I just got out of a 5-day ayahuasca retreat in the Sacred Valley of Peru. It was the most intense experience of my life. My demons left my body or were sucked out by the shaman, literally through my belly button and head. I saw other universes and experienced them deeply. I now know my purpose in life. Ayahuasca isn't a drug. It's a medicine. It needs to be respected and practiced in the safest environment possible.

   I tripped for 8 hours straight and experienced complete ego death, and was reborn on the 3rd night. It was so intense, challenging, and incredibly hard on the body and mind. However, it was so beautiful. I received reassurance about my life and place on the Earth.

4. DXM

   Dextromethorphan (DXM) is a synthetic substance found in many over-the-counter cough suppressants. At high doses, it produces dissociative and hallucinogenic effects through action on NMDA receptors. DXM also affects serotonin reuptake and sigma receptors in the central nervous system.

   DXM is dextromethorphan (brand name Romilar) and is a non-narcotic cough syrup. It's related to the natural opiates codeine, morphine, and thebaine. Those molecules are all levo substances and lose their addictive and narcotic properties as a dextro-enantiomer. It can cause very mild hallucinations at very high doses together with drowsiness, nausea, and respiratory depression. It's only used to cut with other potent drugs to enhance their effects.

   Saying that this molecule is a hallucinogenic drug is ridiculous. It's not even scheduled as a controlled substance and is an over-the-counter antitussive. Most of the comments I read here about DXM are nonsense (I'm sure they even didn't try it). To put this on number 5 on this list above mescaline, LSD, and many others is even more ridiculous.

5. LSD

   Lysergic acid diethylamide (LSD) is a synthetic hallucinogen derived from ergot fungus. It alters perception, mood, and cognitive processes by stimulating serotonin receptors, particularly 5-HT2A. LSD is typically ingested orally and has effects lasting up to 12 hours.

   Absolutely, hands down, LSD is my favorite hallucinogenic so far. I would say DMT is, although DMT is not even comparable to a psychedelic drug. In my opinion, DMT should be in its own classification, completely different. Anyway, I've done LSD 15 times. I love it. I highly suggest it for new timers, as long as they choose the correct dose and test the LSD.

   It was an eye-opener for me and my life in a dark time. I was extremely suicidal at the time, considering committing suicide after the trip (pre-planned before the trip). But that night I took the tab, I was blown away by the amazement of life and its beauty. I realized every single human's importance, including myself. The colors I saw were purple, green, and blue. They would repeat in a circle, and letters and numbers on my phone would wiggle and dance. The air was wavy, and objects were breathing. I felt amazing, pure euphoria and happiness.

   Anyway, after my first trip, I did it 14 more times, and I plan to continue. I've had one hellish experience, but it was because I smoked a little too much weed with it, and my visuals were very strong. I began feeling sick, and my eyes hurt like hell. This caused anxiety and fear, and I eventually was convinced I was dying. But despite one bad experience, I highly recommend this amazing drug. Just don't smoke weed unless you are very experienced, or if weed doesn't cause you much paranoia like it does for me.

6. Mescaline

   Mescaline is a naturally occurring psychedelic alkaloid found in cacti such as peyote, San Pedro, and the Peruvian torch. It acts primarily as a serotonin receptor agonist, particularly at the 5-HT2A site. The effects include visual hallucinations, altered thought patterns, and intensified sensory perception.

   Mescaline, from San Pedro or Trichocereus bridgesii (the female of San Pedro cacti), is reported to have the highest mescaline yield compared to any other member of the San Pedro family. I know because I tried Peruvian torch and San Pedro. Mescaline from San Pedro is very underrated. I've tried psilocybin mushrooms more times than I can count, LSD like 10 times, and also 25i-NBOMe. Mescaline was the last psychedelic I've tried recently.

   The trip comes on very gently, almost sedating while coming up. The euphoria is close to that of pure MDMA. The trip will start around your second hour at the most, peaking around the 4th hour. The visuals are very subtle and complex, depending on the dose. The duration of the trip is 10-15 hours, so it's best taken early in the day. Low lighting plus music will intensify the visuals.

   To prepare, brew 12-14 inches of San Pedro or Achuma (the female). Brew the cacti for at least 4-6 hours, freeze the cuttings overnight, thaw, then blend, also adding ascorbic acid (vitamin C) 1000mg for every 12 inches. This process will extract more alkaloids from the cacti. Honestly, this should be at the top, or tied with DMT. The insights from this special molecule cannot be put into words.

7. Salvia Divinorum

   Salvia divinorum is a psychoactive plant native to Mexico traditionally used in spiritual practices by the Mazatec people. Its active compound, salvinorin A, is a potent kappa-opioid receptor agonist. The effects of Salvia are intense but brief, usually lasting only a few minutes.

   Salvia is weak. My friend bought a half ounce for 60, and he started tripping hard only after using more than a quarter. Do not expect this to taste good, either. It doesn't taste bad, just very unique. But even if you were to smoke enough to start tripping, it would be quite similar to taking a couple of microtabs. No visuals, you just feel wired. Mixing it with weed is ideal because it creeps up on you along with the weed high and gives it the extra boost it clearly lacks when smoked by itself.

   Salvia is one of the most powerful drugs on the planet. Just because you can buy it at shops and online, don't underestimate this drug. I didn't get a nice feeling from it. It felt like I had gravity pulling me backward. Very visual if you get higher doses of it. I suppose I'm glad I've tried it. The only upside to it is that it only lasts about 10 minutes.

8. Peyote

   Peyote is a small spineless cactus that contains the psychedelic alkaloid mescaline. It has been used traditionally in Native American rituals for spiritual and religious purposes. Consumption induces visual hallucinations, altered perception, and emotional shifts lasting up to 12 hours.

   Just watch Beavis and Butthead Do America, and you'll agree with this one.

9. 5-MeO-DMT

   5-MeO-DMT is a potent psychedelic compound found in certain plants and in the secretion of the Colorado River toad. It acts primarily on serotonin receptors and produces rapid onset effects often described as intense and ego-dissolving. Its duration is typically shorter than DMT, lasting about 15 to 45 minutes.

   By far the most intense psychedelic on the planet, in my experience. With one toke administered by an extraordinarily experienced modern medicine man, I experienced multiple tantric orgasms for 20 minutes straight while doing yogic backbends. The orgasmic feeling in my chest endured intensely for 3 days afterward, and more subtly, although completely visceral and palpable, for about two weeks. (I am still able to enter that space without any touching, just through concentration of energy.) After the orgasms subsided, I experienced pure bliss. Soundlessness, complete stillness. The entire experience lasted for about an hour. It changed my life, for the better.

10. 2C-B

    2C-B is a synthetic psychedelic from the 2C family first synthesized by Alexander Shulgin. It has both hallucinogenic and empathogenic effects, acting as a partial agonist at serotonin receptors. Typically taken orally, its effects last between four and eight hours.

    I did this together with my girlfriend a few days ago. She had never tried any psychedelics, while I had. I took 2 pills, and she took 1. After half an hour, we felt super floaty, and the furniture in my room started shapeshifting. I started playing the piano and felt the music through my body. Then, I looked at my hands, and they were growing larger and larger. Now was the moment where it really started to kick in.

    My sister was home, and I didn't think she would come and bother us, but she randomly came into my room wearing a Viking dress she had made herself for a school project. I thought it was so cool! I told her how awesome her dress was and took a picture of it for her. Even though it was a brown dress, it appeared so bright to me! I didn't feel awkward while talking to her, and I don't think I sounded weird to her because she didn't ask me anything strange. She didn't notice anything!

    I turned back when she left the room and saw my girlfriend sitting on the bed. I just had this urge to kiss her. It was the best feeling ever. I held her in my arms as we watched everything in my room change patterns and colors. It was like we were watching a 3D movie. I saw everything double or triple. Then we made out for about an hour, and I'm telling you, sex on this stuff is amazing!

    After that, the effects started to go away, but we still went for a walk at a park nearby my home. I felt a huge connection with everyone walking around in the park, and the colors were so bright.

The Newcomers
11. ?

    AL-LAD

    AL-LAD (6-allyl-6-nor-lysergic acid diethylamide) is a synthetic psychedelic in the lysergamide family, closely related to LSD. It acts on serotonin receptors and produces visual effects, euphoria, and altered time perception. AL-LAD is typically taken in blotter form and has a duration of 6 to 10 hours.

12. ?

    Tma2 (Trimethoxyamphetamine 2)

    TMA-2 is a psychedelic amphetamine from the trimethoxyamphetamine family, first synthesized in the mid-20th century. It produces altered visual perception, mood changes, and thought disturbances by acting on serotonin receptors. Its effects typically last between 8 and 12 hours when taken orally.

    This is a real hallucinogen. It has synergic properties, meaning that your senses change. You can see or smell music, feel and touch something that is not there, and so on.

    Take this drug only when you know what you are taking, because it can also give you panic attacks if you do not understand what is happening. If you are prepared for it, it is a fun experience.

The Contenders

13. Cannabis (Marijuana/THC)

    Cannabis contains the psychoactive compound delta-9-tetrahydrocannabinol (THC), which binds to cannabinoid receptors in the brain. THC alters mood, perception, and cognition, and may cause mild hallucinations at high doses. The effects vary depending on dosage, route of administration, and individual tolerance.

    Yes, believe it or not, folks, cannabis can be considered a psychedelic. I don't know about other people, but when I smoked it, everything had something out of the ordinary that I would never have known or heard until I was "high." Movies, music, and even life itself had something new to it. And I must say, if you've never experienced this for yourself, well then you must be smoking some pretty weak stuff, or maybe you're just too ignorant to even pay attention to things that deep. Everyone is entitled to their own opinion. And for that fact of the matter, I just happen to believe that cannabis is a psychedelic medication. I mean, after all, it is mind-altering.

14. Datura

    Datura is a genus of plants containing tropane alkaloids such as scopolamine, atropine, and hyoscyamine. These compounds produce deliriant hallucinations, confusion, and memory disturbances by blocking acetylcholine receptors. Datura has a high risk of toxicity and unpredictable effects.

    Don't do this. It can and will kill you if you don't know the exact dose you are taking, and it's very hard to know the dose. This is a deliriant, different from a psychedelic/hallucinogenic, as you can't differentiate between the hallucinations and what is real. Incredibly dangerous.

    Datura is, according to me, the best deliriant or hallucinogen. The experience is intense. One wouldn't even know he is tripping. You might find yourself talking to strangers, thinking they are people you know, or speaking randomly to people. You experience a sense of free will and unstable walking. My legs were bent like a crab. There are balance problems, and you might find yourself speaking nothing but the truth. It's the scariest drug you can have, but an overdose can kill you. There is a very fine line between the actual dose and the lethal/toxic dose.

15. Ketamine

    Ketamine is a dissociative anesthetic that produces hallucinations and out-of-body experiences at sub-anesthetic doses. It primarily acts as an NMDA receptor antagonist in the brain. It is used medically for anesthesia and increasingly researched for its antidepressant properties.

    This is one of the only drugs, besides nitrous oxide, that when done in excess can lead to an out-of-body experience. Ketamine is designed to induce a state of paralysis for animals about to go through surgery. When one becomes stuck in the K-hole, this is when they experience a near-death experience that is literally impossible to describe to anyone, even to yourself.

    If you have ever fished out off of nitrous, then you may have some idea of how potent of an experience this is. If one reaches the hole, they can stay there for 3 hours. Since it makes it difficult for the user to experience pain or move for that matter, it is often used as a drug for date-rape.

16. Iboga

    Iboga is a shrub native to Central Africa containing the psychoactive alkaloid ibogaine. Ibogaine affects multiple neurotransmitter systems, including serotonin, dopamine, and NMDA receptors. It is used in traditional rituals and studied for its potential in addiction treatment.

17. 25I

    25I-NBOMe is a synthetic hallucinogen derived from the 2C family, specifically 2C-I. It is a potent serotonin 5-HT2A receptor agonist that produces vivid hallucinations and altered perception. The compound has been associated with severe health risks and fatalities at high doses.

    My first psychedelic. I loved it.

18. Morning Glory Seeds

    Morning glory seeds contain ergine (LSA), a naturally occurring psychedelic compound structurally similar to LSD. Ingesting the seeds can induce visual distortions, introspective thoughts, and altered time perception. The effects typically begin within an hour and can last several hours.

    This one really blows. I have tried nearly everything on this list, and I like to trip to the point where people think I won't come back. When I heard about this, I tried a ridiculous amount (600-700) expecting to blast off. Although I blasted off, it was more like a blast off of my stomach rupturing. Imagine LSD, but instead, you are sick, queasy, and the overall body load is about 4 times that of LSD.

    I have tried this a few times, starting with 600-700 the first time, then 500, 400, then 250. Even at 250, I became sick, and around 300-400 is when you will truly trip, but they will make you very sick. Euphoria feels like the body "forces" you to feel euphoric, which doesn't feel euphoric at all, I suppose.

19. DOM (STP)

    DOM, also known as STP, is a long-acting synthetic psychedelic from the substituted amphetamine class. It is a 5-HT2A receptor agonist that induces intense visual hallucinations and stimulation. Effects can last from 14 to 20 hours or more.

    The strongest psychedelic I've done. I've tried almost all listed. I received it on stamps and ingested two stamps. About 10 people took it with me at the same time. When it hit us, everyone blacked out and came to while we were walking down the street 5 minutes later. It was super intense visually, the strongest hallucinations I've ever seen, and I've done everything. I originally thought it was LSD, but after taking LSD a lot, I found it not even slightly comparable in the magnitude of visuals. We would become so flabbergasted at what we were seeing that we were literally unable to communicate.

    It was like combining speed with LSD. Not my thing.

    Either way, I found out that once you break through, you only need a small dose of psychedelics to do it again. Try to meditate in your trip, clear your mind while tripping. When you're able to do so, you can rebuild your ego from the ground up. Peace.

20. PCP

    Phencyclidine (PCP) is a dissociative drug originally developed as an anesthetic before being discontinued for medical use. It acts primarily as an NMDA receptor antagonist, producing hallucinations, detachment, and sometimes violent behavior. PCP has a high potential for abuse and neurotoxicity.

    I had my weed laced with it once. It's far more powerful than DXM. It's slightly stronger than acid, but it is completely different. I would not recommend taking this substance. If you want a good experience, smoke weed. If you want something stronger, eat some mushrooms or take some acid. This stuff is not fun. It's insane.

    I tried it. It was overall fun but very inconsistent. Some trips were great, while others were scary and unpleasant. It never made me take off my clothes and run around on the streets. In fact, I'd be lucky to be able to make it to the bathroom on that stuff. I'm retired from PCP.

21. Diphenhydramine (Benadryl)

    Diphenhydramine is an over-the-counter antihistamine that, at high doses, can cause deliriant hallucinations. It works by blocking acetylcholine and histamine receptors in the brain. The hallucinogenic effects are often accompanied by confusion, dry mouth, and sedation.

    Diphenhydramine was my second hallucinogen, and I thought it was great. I saw bugs, had lucid dreams, and also felt a drunk-like sensation. I couldn't walk straight.

    The next day, I felt so heavy I could barely stand at first, but it got better around the third period at school. I could easily pass out in school, in all my classes, and even for a few seconds. There was a lot of confusion and forgetting that day, and on the third day, I had a headache. Most people didn't like it, but I'd do it again.

    This is wild. Even at pretty low doses, it makes you feel like a drunk fat slug, kind of like DXM at high doses but with more delirium and body load, at least for me. It's fun as hell when smoking weed with it. You get weird movie scene hallucinations, and you feel like paparazzi is around you with cameras asking questions, but it's just your mind.

22. Ergine

    Ergine, also known as LSA (lysergic acid amide), is a naturally occurring compound found in morning glory and Hawaiian baby woodrose seeds. It is chemically related to LSD and can produce mild hallucinations and dream-like states. Its effects are generally less intense and more sedative than LSD.

23. MDA

    MDA (3,4-methylenedioxyamphetamine) is a synthetic compound structurally related to MDMA and amphetamines. It produces both stimulant and hallucinogenic effects by acting on serotonin, dopamine, and norepinephrine systems. MDA is known for its empathogenic effects as well as visual hallucinations at higher doses.

    What are you talking about? Have you ever taken LSD? Thoughts and visuals like LSD? MDMA is Methylenedioxymethamphetamine, and MDA is Methylenedioxyamphetamine. It's less potent than MDMA, and MDMA has no frank hallucinogenic properties. And you're saying that MDA is better and closer to LSD? For your information, Ecstasy is in the category of Phenylethylamines, and LSD is in the category of Tryptamines.

    I had MDA once, a healthy bump to pass the time while waiting for some acid to kick in. It was pretty much like candy flipping in one drug, with euphoria like E and thoughts and visuals like LSD. Geometric strobes in primary colors dominated my peripheral vision, while my focus was either super clear or melty. I would totally choose this over MDMA any time.

24. Bromo Dragonfly

    Bromo Dragonfly is a potent hallucinogenic compound in the phenethylamine class. It acts primarily as a serotonin receptor agonist and can produce long-lasting psychedelic effects, sometimes exceeding 24 hours. The drug has been associated with severe vasoconstriction and toxicity in overdose cases.

    Melts your whole body and mind. A totally amazing trip.

    Slightly less potent than LSD. A type of synthetic acid. Lasts for a good 10 to 12 hour trip.

25. 4-AcO-DMT (O-Acetylpsilocin)

    4-AcO-DMT is a synthetic psychedelic thought to be a prodrug of psilocin, the active compound in magic mushrooms. It is chemically similar to psilocybin and produces comparable hallucinogenic effects. The substance is typically consumed orally and can lead to visual distortions, altered thinking, and introspection.

    Probably in between DMT and psilocin, this one really is intense because generally, if you have this, you can measure out what you're taking. A 20 mg hit can have you totally absorbed, and it's not even considered a heavy dose.

    It provides much more of a body high than LSD or even an eighth of cubensis, in my humble opinion. It feels like small, pleasant electric jolts on every nerve ending, and the visuals fractalize in a highly geometric, angular, sharp way.

    I definitely could not hold myself together in public or with other people at home, and I could barely walk around my small room during the first 4 hours. The experience had mystical and natural overtones.

26. 4-HO-MET (Metocin)

    4-HO-MET is a synthetic tryptamine derivative with psychedelic effects similar to psilocin. It acts on serotonin receptors, particularly 5-HT2A, to produce visual and cognitive alterations. The compound is typically used recreationally and has a duration of 4 to 6 hours.

    Amazing experience. Light headspace, interesting visuals, and always a great time.

    Ego-centric psychedelic that is in between MDMA and mushrooms. It can be enlightening if used correctly.

27. Harmaline

    Harmaline is a naturally occurring beta-carboline found in plants like Banisteriopsis caapi and Peganum harmala. It functions as a reversible monoamine oxidase A inhibitor (MAOI), often used to potentiate the effects of DMT in Ayahuasca. Harmaline itself can produce mild visual effects and changes in consciousness.

    Incredible, but not for the faint of heart.

    Be sure to prepare your mind before trying this.