Best Binding of Isaac Characters

I'm going to be talking about the AB+ versions of the characters as it is the most recent version of the game. I won't put Eden on the list as he is too random to be able to judge fairly.

The Top Ten

1 Samson

He was better in Wrath of the Lamb. - Bloodbirth-HQ

If you play your cards right, the amount of extra damage you can get is absurd. While the most obvious idea is to use a blood bank, other benefits include getting something extra from mimics or curse rooms, and being able to destroy everything at a much faster rate. - kempokid

2 Judas

If only his health was higher I would use him more often. Instead, I use Cain and grab the Belial. - Bloodbirth-HQ

Judas is really fun for me, a combination of high damage and extra Devil room chance makes for a fun character that has much more forward momentum than most characters. Also, a 1.35 damage multiplier is insane. - kempokid

3 Cain

An Isaac with less health but better everything! - Bloodbirth-HQ

He has amazing luck and you basically never get anything bad.

While he doesn't have anything particularly amazing about him, his general stats are great, with slightly higher than average damage and a luck upgrade. He's just a great character without any major drawbacks. - kempokid

4 Isaac

The D6 makes him overpowered. - Bloodbirth-HQ

Though he doesn't have any particular gimmicks or special abilities, starting with the D6 (arguably one of the best items in the game) is a massive perk, as you are not as susceptable to bad RNG. Also good alround stats, and starting with a bomb is nice.

The fact that you start with the D6 is ridiculous, especially in AB+ where good items are already fairly common. You are almost guaranteed to have a broken run by the end of the game if you play as Isaac, at least until the booster packs fixed this issue, making him a more balanced, fun character - kempokid

D6 for the win.

5 Eve

Definitely not good - Bloodbirth-HQ

If she didn't have the razor, she would easily be the worst character, but the razor really makes her great. The encouragement to spend a lot of health on deals is also quite nice, but now that you can have your powered up state much more consistently. - kempokid

I meant other than the character intentionally made to be garbage - kempokid

6 Lilith

I like her design but as a character, no. - Bloodbirth-HQ

I don't like her ever since the box of friends was nerfed, as most of the time she was essentially an average character with a hard to aim shot. - kempokid

7 Lazarus

When you grab Dead Cat, Broken Ankh, and Ankh in one run with Lazarus you know you are unstoppable - Bloodbirth-HQ

The king of minmaxing

I don't understand the hate for this guy, the amount of minmaxing you can do in order to get an amazing character isn't something that should go unnoticed. Bloody Lazarus can be gotten in some extremely beneficial ways, such as taking extra Devil deals. - kempokid

8 Azazel

Okay, my first run with him didn't go well, but when I did my second one, I did a whole lot of runs in one game. I had gotten blast damage, poison damage, common cold, and many other deadly things! - Bloodbirth-HQ

Who wouldn't like him? High damage and flight?! Definitely my go to character. Besides Maggie, I used him to unlock most of the characters in the game

Personally, Azazel is my favorite character, he deals a lot of damage, and rocks/cracks are no longer a problem, since you can fly. The only thing wrong is that you can't use all the red hearts you find, since you can only have soul hearts.

Use the ludovico technique and your low range is no longer a problem, plus you can annihilate bosses within seconds. And the free flight is also amazing. Range up pills are also really helpful - Lanturnizer6

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9 The Lost

The Lost is my personal favourite character, the addition of the holy mantle has made him extremely fun, as stupid damage out of nowhere won't kill you as often. The reason I love him is thanks to being able to take Devil deals for free, giving you an extreme offensive boost. - kempokid

10 Apollyon

He could definitely be better. So could my grammar - Bloodbirth-HQ

While he could work similarly to Isaac, and the void is a cool item, I find it to be quite limited in terms of,what to get rid of, as many items are worth more than what the void will give you, and there is a chance of getting range ups and other pointless stats. - kempokid

I'm not worried about them as much as it's just annoying to get them. Also, due to the about of items in the game, the chances are extremely low of getting it on a run - kempokid

The Contenders

11 The Forgotten

I find him... difficult - Bloodbirth-HQ

It's the most complicated character
and a fun one too

I think The Forgotten will become a close #1 soon. He has unique synergies and a unique tag-team system. - mattstat716

He’s the most interesting character, and I love the addition of him starting with both melee and spectral tears, he’s the lost but chained to a skeleton body, and has health.

12 Magdalene

I honestly think Magdalene is far too underrated. With a single speed boosting item, she instantly becomes viable and her high health allows her to safely make devil deals early on - Lanturnizer6

While the extra health is kinda nice, the decreased speed is not a very good tradeoff. - kempokid

13 ???

He can spawn poop... OVERPOWERED - Bloodbirth-HQ

As a challenge character, he serves his purpose adequately, however, I don't find him to be good at all. The lack of regular heart containers makes taking any devil deal much less worthwhile, and the poop is a terrible active. - kempokid

14 Eden
15 Keeper

It's really no surprise that this guy sucks, he feels poorly balanced even as a challenge character in my opinion. - kempokid

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