Best Binding of Isaac Characters

I'm going to be talking about the AB+ versions of the characters as it is the most recent version of the game. I won't put Eden on the list as he is too random to be able to judge fairly.

The Top Ten

1 Samson

If you play your cards right, the amount of extra damage you can get is absurd. While the most obvious idea is to use a blood bank, other benefits include getting something extra from mimics or curse rooms, and being able to destroy everything at a much faster rate. - kempokid

2 Judas

Judas is really fun for me, a combination of high damage and extra Devil room chance makes for a fun character that has much more forward momentum than most characters. Also, a 1.35 damage multiplier is insane. - kempokid

3 Cain

While he doesn't have anything particularly amazing about him, his general stats are great, with slightly higher than average damage and a luck upgrade. He's just a great character without any major drawbacks. - kempokid

He has amazing luck and you basically never get anything bad.

4 Eve

If she didn't have the razor, she would easily be the worst character, but the razor really makes her great. The encouragement to spend a lot of health on deals is also quite nice, but now that you can have your powered up state much more consistently. - kempokid

I meant other than the character intentionally made to be garbage - kempokid

5 Isaac

The fact that you start with the D6 is ridiculous, especially in AB+ where good items are already fairly common. You are almost guaranteed to have a broken run by the end of the game if you play as Isaac, at least until the booster packs fixed this issue, making him a more balanced, fun character - kempokid

Though he doesn't have any particular gimmicks or special abilities, starting with the D6 (arguably one of the best items in the game) is a massive perk, as you are not as susceptable to bad RNG. Also good alround stats, and starting with a bomb is nice.

6 Lilith

I don't like her ever since the box of friends was nerfed, as most of the time she was essentially an average character with a hard to aim shot. - kempokid

7 Lazarus

I don't understand the hate for this guy, the amount of minmaxing you can do in order to get an amazing character isn't something that should go unnoticed. Bloody Lazarus can be gotten in some extremely beneficial ways, such as taking extra Devil deals. - kempokid

The king of minmaxing

8 The Lost

The Lost is my personal favourite character, the addition of the holy mantle has made him extremely fun, as stupid damage out of nowhere won't kill you as often. The reason I love him is thanks to being able to take Devil deals for free, giving you an extreme offensive boost. - kempokid

9 Azazel

Despite the high damage and flying, I hate Azazel, as well as having basically no range, most synergies, and by extension items, become useless. End game is also awful as bullet hell bosses are ones that you should stand far away from, not get up in their faces. - kempokid

Use the ludovico technique and your low range is no longer a problem, plus you can annihilate bosses within seconds. And the free flight is also amazing. Range up pills are also really helpful - Lanturnizer6

10 Apollyon

While he could work similarly to Isaac, and the void is a cool item, I find it to be quite limited in terms of,what to get rid of, as many items are worth more than what the void will give you, and there is a chance of getting range ups and other pointless stats. - kempokid

I'm not worried about them as much as it's just annoying to get them. Also, due to the about of items in the game, the chances are extremely low of getting it on a run - kempokid

The Contenders

11 The Forgotten

I think The Forgotten will become a close #1 soon. He has unique synergies and a unique tag-team system. - mattstat716

It's the most complicated character
and a fun one too

12 Magdalene

I honestly think Magdalene is far too underrated. With a single speed boosting item, she instantly becomes viable and her high health allows her to safely make devil deals early on - Lanturnizer6

While the extra health is kinda nice, the decreased speed is not a very good tradeoff. - kempokid

13 ???

As a challenge character, he serves his purpose adequately, however, I don't find him to be good at all. The lack of regular heart containers makes taking any devil deal much less worthwhile, and the poop is a terrible active. - kempokid

14 Eden
15 Keeper

It's really no surprise that this guy sucks, he feels poorly balanced even as a challenge character in my opinion. - kempokid

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