Top 10 Worst Fandoms and Groups On the Internet
Don't get me wrong. I like My Little Pony just as much as any other average fan. There are several episodes that made me laugh, some that made me cry, and some that made me smile. Yes, certain episodes are cheesy, but others are genuinely well-written, and you can tell effort was put into the art style.
As for the fandom itself, I strongly believe it's at the top of the most annoying list because of the radical fans. I'm not talking about the ones who cosplay just for fun, have thoughtful discussions about the show, or even create art. I'm talking about the crazy 5% who sexualize the characters, engage in shipping wars, and behave immaturely at conventions. Show some self-control and make our fandom look better, please!
Well, if you use logic, a year in our time is about 365 days, right? So every year, you get older by one year. Other countries have had, or still have, different calendars that indicate one year is not 365 days. For example, a calendar from one country might say that 600 days make up a year, and by that measurement, you could be 7 years old, whereas in the U.S., you'd actually be 40.
So what does this have to do with Bronies?
It's simple. If you took the foreign calendars and used their time measurement, you could, in theory, say you're maybe just 5 years old instead of a 40-year-old guy, and therefore partially justify being a Brony.
Listen. I don't hate the Fnaf community. In fact I love it! The lore and gameplay is amazing, and I'm a part of this community! But there are two parts of this community. The first part, are the people that love the lore, gameplay, characters, etc. They love to make memes, edits, and play the games. I'm on this side.
But then, there's the second part, where there are people that love the characters so much, that they want to "knock up" toy chica, or have s*x with the selfish wolf in security breach. They want to look at "Rule 34" and most likely have wet dreams about the characters they simp for. This is the horrible side.
Don't hate the entire community because of the bad side. It's only those people that should be shunned.
The gameplay was unique and new when the first game came out. But the later games are more of the same or a similar thing. The only thing keeping me hooked is the story. However, fans blow things out of proportion. They seem to have an attachment to certain animatronics, despite those animatronics not being real. They're characters made up by whoever owns the establishment.
The shipping is annoying, and don't get me started on the fan art. But the worst are the fans who come up with theories and then treat them like facts. They think MatPat is their god.
Back in 2012, I thought Bronies were the worst, but two or three years later, I see the Five Nights at Freddy's fanbase, and suddenly I feel like Bronies are all right.
I love the show, don't get me wrong, but the fandom is horrible. Let me state the reasons. For example, almost driving an artist to suicide because her interpretation of a character was "too skinny." Flooding an actual Keystone Motel's reviews section (that was named long before the episode came out) with comments about things that happened in the episode. Almost every time a fan comes out with a new character, they will bash it. The homophobic part of the fandom will continue to deny there is a canon lesbian couple. I have also heard that people are leaving the fandom because the creator came out as bisexual. R34 and Mary Sues are common in fandoms, so I won't say much about that. This fandom is so terribly strong that even Rebecca Sugar herself had to call them out on their actions.
I'm a Steven Universe fan, but 50% of the fandom is just way too aggressive. They're overprotective of the characters simply because Steven Universe portrays them as real and relatable. Personally, I think the show is awesome. The story is well-written, the world-building is incredible, and the characters are well-fleshed-out. The show is light-hearted most of the time but can also go incredibly dark.
But my goodness, the fans can be crazy. People who draw the chubby characters just a little bit thinner receive insane backlash and even death threats. I remember one incident where an artist drew a dark-skinned character with a lighter skin tone due to lighting effects and received hate messages. Another person drew a chubby character a bit skinnier and was bombarded with over 30 hate blogs and hate mails, nearly leading them to take their own life. A Japanese artist also faced hate mail for drawing Garnet with a lighter skin tone. These characters are literally aliens. While I understand that Garnet is meant to represent a Black woman, let people draw what they want. Not everyone knows how to draw varied body types. They're still in the process of learning.
I sometimes really hate the fandom. Although it generally has a good community, which thankfully I encounter 99% of the time, some fans are just overly aggressive social justice warriors. Many people avoid watching Steven Universe because of these extreme fans, and that's unfortunate because they're missing out on a great show. This behavior isn't what Rebecca Sugar, the show's creator, intended. The message of the show is to spread love to everyone, regardless of their skin tone, body type, or personal preferences. But some fans seem to forget about this message. They resort to hate and harassment, which is really sad. Criticism is one thing, but sending death threats and insulting artists is another.
They never have any good reasons to dislike something. It's always, "Well, the fandom is absolute garbage," typed angrily in the YouTube comments. A bad fandom generally isn't a reason to dislike something. Unfortunately, that's the way most people who hate something tend to react.
If the person has a serious mental condition, such as social anxiety, chronic depression, or bipolar disorder, they could take it the wrong way. If death threats are involved, they could possibly commit suicide - all at the hands of a long, spiteful YouTube comment.
Sadly, I have multiple friends like this. They don't listen when I try to reason with them about why I like something. They start unnecessary, unwarranted arguments for no reason whatsoever. Most of them are completely disrespectful, much like most anti-fans or haters on the Internet, if you ask me. They are rude and don't listen to reason.
Some of them aren't bad people. They just want to explain why they don't enjoy the TV show, movie, video game, book, book series, et cetera. Most of the time, it's these people who have logical reasons to dislike something. It's kind of sad when you think about it.
Let's not forget that the Sonic fandom also compromises characterization. Knuckles is not stupid, Tails is not annoying, and Shadow is not a bloodthirsty murderer or Blood Knight who goes around killing people for fun without emotion. Cream is not sexy, and Blaze is not Felix the Cat's love interest, to name a few. Don't even get me started on the horrible shipping wars. I'm so sick of them, and none of the Sonic couples are official. Knuckles and Rouge are rivals, but that doesn't make them a married couple. The same goes for Sonic and Shadow. The shipping wars become even worse with crossover shipping. Sonic and Rainbow Dash have never met, and he would be much more interested in Amy Rose than in some sparkle-poop colored horse that flies over the rainbow.
I really love the Sonic the Hedgehog series, but I just can't stand the fandom. For some reason, they hate every single game, even those that haven't been released yet! You can't really voice your opinion or discuss something you like because you will be met with immediate hate.
Let's say there's a fan of Sonic 06, which is considered to be the worst game ever for those who don't know, who wants to discuss the game. Well, there you have it: the most hated game, but it appears some people like it after all. This leads to conflict every single time because people there hate everything and can't accept that someone might have a different opinion. I'd much rather call them anti-fans. If you don't like something, why join a group? Why spend your own money on the game? If you're not a hater, you won't be welcome in this fandom. I plan to enjoy the adventures of the blue blur while staying out of the fandom.
I love anime. I didn't vote for this because I hate anime. There are so many different kinds of anime. It's impossible to hate all of it. What I do hate are people who are so obsessed with anime that they dislike anything that isn't anime and/or want to be Japanese. Other countries produce good content as well. Try watching Over the Garden Wall or something similar. I feel that most people claim to hate anime just because of these obsessed fans. Most people who say they hate anime haven't even seen one, and you know why? It's because of these people. So please, don't vote for this because you hate anime. Vote because you dislike the weebs.
Personally, my hatred for this fandom comes from my classmates and other people on the internet. They all think that cartoons and anime are very different in the show's target audience. They can't even distinguish what's a western cartoon or anime. They treat cartoons very poorly, and they always tease someone or call them names like 'childish', and they will tell you to grow up while most of the anime they watch is very perverted, like Boku no Piko. I also like anime, but I think many people here in this fandom discriminate against the Western or any animations that didn't come from Japan.
Idiots nowadays are known as members of the Bro Army, and their idol is PewDiePie. These idiots see their idol as nothing less than the god of everything! If you even so much as whisper a bit of criticism towards their "lord and savior," you will get enough hate to probably quit whatever site you received that bashing from. This hate often comes from the cringe-worthy statements they scream. I won't post an example of this hate, but even the haters can be seen as insane. Just look at the channel known as "PewDiePie Sucks," where there are re-uploads of hater videos from people like pre-2016 Malcom1466 and that one guy who said that PewDiePie is "molding kids' brains."
Even though I am a "bro" or whatever (I have been since about March of 2012), his newer fans are so annoying! They stand up for everything he does. If people say one damn thing about him, the tiniest thing, they go ballistic. I really do like him, but now that everyone knows about him, it's gotten annoying. I mean, it's so annoying to be in school when a girl (I'm a girl too) makes a reference. Just shut up, and thank you.
I hate furries with a burning passion. They genuinely think they are an animal, and they walk around wearing hot-as-hell suits all the time. The furry fandom has also ruined the Zootopia fandom.
Before I delve into this, I want to clarify that I am a furry myself. I know for a fact that the atrocious and repulsive actions that come from the fandom represent only a small, obsessively engaged 5% of the group. However, this minority is so active and violent that they become the focal point, overshadowing the remaining 95% who are not involved in such disturbing behavior.
When someone reveals their furry identity, even subtly, such as by using fur art as a profile icon, everyone on that forum (or blog, page, etc.) immediately jumps on that person. They accuse them of numerous things, irrespective of whether they are discussing the topic at hand. This kind of harassment continues until the targeted individual is emotionally devastated.
The fanbase wouldn't be so negatively viewed if this dark subsection of its members weren't so violently prominent, causing people to focus solely on them instead of the community as a whole. Everything I've mentioned above is based on real experiences. I deal with this backlash every time I post or comment on a video, even when my comment is on topic.
These individuals don't realize that they're perpetuating the stereotype that women are the weaker sex by getting angry over seemingly trivial issues. Taking offense at something that appears harmless can be perceived as a sign of weakness. They don't understand that they are undermining the reputation of women. Feminism wasn't always like this. Historical figures like Susan B. Anthony would likely be dismayed by these developments. The people I'm talking about can be considered among the biggest hypocrites in history.
If a fictional female character is weak, they complain. If she's strong, they still complain. If she's beautiful, they still complain. If she's unattractive, they still complain. If she's virtuous, they complain. If she's evil, they still complain. Essentially, they seem to dislike any characteristics and personalities that a female character could possibly have. What bothers me the most is their inconsistency. They complain about scantily clad female characters, but even if the character is fully clothed, they still find something to complain about. They dislike both extremes. What these individuals fail to realize is that these female characters aren't created to offend women. I'm a woman myself, and sometimes I'm ashamed of being female because of these misandrists who continually embarrass the female gender.
Oh my, this is going to be fun. Being a Justin Bieber hater may sound like an oxymoron, but yes, I am that one girl who loves music of the metal genre and awesome bands like Rammstein, Ost+Front, Judas Priest, etc., but cannot stand Justin Bieber. Why? Because, not to mention that pop music often gets on my nerves, listening to his whining, which they call "singing," makes me burst into laughter. His songs consist only of stuff like, "Babe, I want you. I want to take you away," and so on (very similar to One Direction, which I also hate).
Additionally, he once said about a Holocaust victim that if she had remained alive, she would have become his fan. Really? And these rabid fans may actually worship him? God, I cannot even understand how one can actually worship and stand for this, especially with such fury.
How are Beliebers not number one? They're mostly a group of teenage girls who will defend Justin with their lives. If you ask them why they like him, they'll tell you it's because he's hot. Even if you point out that he's done bad things, they'll say something like, Oh, he's Justin Bieber, so he can do anything he wants. Many of them will literally worship him.
One person started a massive argument in a YouTube comment section. When told that JB has even spat on his fans, he (yes, it was a he) said, And? JB's saliva is delicious. If you ask me, they're all mentally challenged. Even Directioners are better than them.
Why 90s kids are annoying:
1. Their "cutoff dates" are horrible. Someone once said that a 90s kid is born from 1989-2001. 2001 wasn't even in the 1990s!
2. They think that Invader Zim, Jimmy Neutron, That's So Raven, and FOP are 90s shows. Seriously, how bad is your memory?
3. They think that 9/11 was the only thing that happened in the 2000s.
4. They think that Angela Anaconda, Rocket Power, and Mega Babies were good! All three of those shows were horrible, and you seriously need to take the rose-tinted glasses off.
5. They claim that the 1990s were the last good decade. That crown goes to the decent 2000s.
I was born in the 90s. However, I'm so sick of people thinking that the 90s were the most godly time to be alive and that everything in the 90s was the best. They even think kids born in the 2000s have bad lives and have terrible taste in everything because they didn't grow up with the things they grew up with. This is so asinine. Why do you have to be so egotistical? Is it nostalgia? Whatever it is, it's annoying, and you all need to get off your high horse.
I played Minecraft again after three years and, seriously, the first thing that happened was some 12-year-old annoying a moderator because he "wanted to be kicked." Even after telling him to stop and that it's immature, he continued. You can't help such people.
Also, hearing Minecraft players talk is horrible. They brag about how many diamonds they've found and what big buildings they've built. And when you tell them you're not a hardcore player with three large chests of diamonds, they instantly kick you out of the conversation.
The game itself is good, especially for creative minds and parties with friends.
I hate Minecraft, but the fans are a different story. They consist of 5- to 10-year-old nerds who think this game is the best ever and that it's their life. They go on servers and just annoy people, talking about pointless things. They also discuss FNAF, another horrible game. Fans of Skydoesminecraft have to be the worst of all. They keep saying "BUTTER, BUTTER, BUDDER." "Squids are evil. Kill them with BUDDER." If you say, "This game is bad," everyone starts attacking you, saying, "How is this game bad? It's the best game ever!" or something like that.
I just can't stand these people.
I don't think the whole fandom is bad. In fact, I believe there are no bad fandoms. There are some One Direction fans who respect opinions and simply love their band without being disrespectful. I've seen some of them here on TheTopTens. However, some fans may not be mean but still don't use sound reasoning. For instance, one time on YouTube, someone commented on a Blink-182 video that the band sucked because they had ugly band members, and that One Direction was better because their members are attractive. I don't mind if someone thinks One Direction is better than Blink-182, but using looks to justify it isn't a good way to express that opinion. How about considering the musical talent of both bands instead?
I was a Directioner, and it was the fandom itself that made me leave. The fandom even made me dislike the boys. Members argue amongst themselves and categorize each other. For example, Larry Stans can be really violent with their words. I've had a couple of fights with them, so I know from experience. Directioners also fight with other fandoms all the time. They think they are the biggest fandom in the world, which they really aren't. I actually feel bad for the members of 1D. I wouldn't be surprised if they harbored some dislike for their own fandom.
Go to a Call of Duty Facebook page, read the comments, and then prepare a mass funeral for all the brain cells you'll lose.
I more or less still follow the series and occasionally encounter some good fans. However, many can't tell when a game is good and when it's basically a playable Michael Bay film. In fact, many don't even touch the story and are actually proud of that. This wouldn't be so bad if the reason was that recent stories have been terrible (not including Advanced Warfare because I haven't played it yet), but I think they just don't care to begin with. And they call themselves fans.
Then there are the casual Call of Duty players who call the more frequent players "nerds," something I don't think real gamers would take kindly to.
And when they do complain, it's usually about campers or weapons that do their job "too effectively."
I love Call of Duty, and most of the fans are totally normal. But every now and then, you run into Timmy-no-thumbs, the screeching 10-year-old who thinks it's the game's fault every time he dies. Or perhaps you've encountered Sir-Complains-a-Lot, the 22-year-old who acts like Timmy-no-thumbs but is less screechy, which, in my opinion, is even more pathetic. Have you met DJ-Wontshutup? He's the guy who blasts rap music into his headset and never says anything.
Again, the vast majority of fans aren't like this. However, these terrible players are so memorable that people have begun to think that all fans are like this, which isn't the case at all.
I agree with this choice so much. Trump fans are some of the most ignorant, hypocritical, and downright deranged people in the world. They go around saying that Trump is the "best candidate ever" and worship him as if he is a god.
At this point, I don't see the value of having a man like Trump be the President of the United States. He is a disgustingly racist and sexist man who can never take "no" for an answer. He makes fun of people with mental disorders, like autism, and denies the fact that he allowed another country to interfere with American politics, which of course is an act of treason. His supporters always give me a headache, and since I live in Pennsylvania, that is often the case.
Seriously, this election is such a nightmare! Hardly anyone even likes the candidates, and the worst person you could possibly imagine is most likely going to become the president. Why do people like this person who is trying to promote violence and sexism? Not to be a feminist or anything, but I've heard some of the things he's said, and it's obvious that he has no respect for women. I actually know someone in real life who's a Trump supporter, and he thinks he can touch and insult women as if they're just objects.
With some of the things he says, though, it's almost as if he doesn't want to be the president. Of course, I wouldn't hate him so much if it wasn't for the fact that people actually agree with some of the things he says! Whoever votes for him is an idiot and should have paid some attention in school instead of smashing up Smarties and inhaling the powder, or whatever weird things these idiots do nowadays. I'm not even kidding when I say this. I am unfortunate enough to know a lot of Trump fans in real life, and they actually do things like that. They even sound drunk when they speak and can't pronounce simple words correctly.
I actually enjoy Hetalia a lot, especially because it's convenient and I learn little bits of history from it. However, the fandoms can be a bit intense. I don't mind if you ship the weirdest things or the most common ships, but don't hate other people for their opinions. Just because you like it doesn't mean everyone has to.
I don't care if you dislike yaoi ships or find a character annoying. It's your opinion, and you should share it if you want. But don't bully people into liking or hating something. Doing so repels people from enjoying the actual anime. The anime is perfectly enjoyable without extreme fans and haters interrupting the experience by forcing me to like or hate something. So to the extreme fans or haters, please respect others and cool down.
I love Hetalia. I've watched every season and special out there. What frustrates me the most is reading the fan fiction that the fan base creates. Apparently, it's totally okay to write the characters as pedophiles or rapists, and even as serial killers, as well as overly possessive dominants over their ships.
Also, flags of the world should never ever touch the ground. Ever. Not even the actual characters themselves toss around their flags the way cosplayers and fans do in photos or artwork. It's offensive and far from the way the show is scripted to be. Those who love the show as much as I do should steer very clear of the fan base if they don't want to be annoyed. It makes me sick and sad.
Literally, these guys on YouTube are out of control. I express my opinion, and they come at me, saying things like, "How dare you hate on (insert terrible person)? They're my favorite! Say that one more time, and I'm coming to kill you."
These people are just losers who want others to think they can bench-press a car. In reality, they can hardly even lift a toy car.
A bunch of kids put USMC trainee images in their avatars and send death threats to anyone who even slightly disagrees with them. These kids are the reason YouTube comments have become so toxic.
I am sorry, Undertale. Sorry for your sudden popularity. The game itself has lots of amazing content, an interesting fighting system, and one of my favorites: the choose-your-own-path feature and different endings. But that very popularity has ruined Undertale's fandom. People want to have sex with skeletons? How on earth is that possible? The other half wants the same thing with a robot. Also, there are the OCs. For some reason, it's always the OC part of every fandom that ruins it. Can't people just make normal, balanced OCs that are not fan-favorite characters with eyelashes and different hair?
Heartwarming game, hideous fandom. Once, I searched online for a Toriel sprite for a little drawing I wanted to make. Seriously, just a sketch of her in her chair, reading about snail pie. I was bombarded with cringe-worthy lewd images of this lovable old woman portrayed in multiple sexual positions. I immediately closed the window in hopes of unseeing what I had seen, but that would be asking the impossible. I absolutely hate this fandom for the most part, except for a few people who do not shove this game down others' throats.
Well, I am a YouTube commenter, and that's true. Most people offend others significantly for reasons I don't even know about. They also show respect for things that are genuinely bad. Take Pamtri, for example. Pamtri has the worst 3D animation on YouTube, yet people pretend to respect it. They use their "praise" as a joke or something of the sort.
Additionally, some commentators warn us about videos that are incredibly scary and provide cautionary links.
YouTube has had a weird sense of humor, both in the past and now. It's just strange overall.
Honestly, this is all Google's fault. If they had never acquired YouTube 12 years ago, many of these hateful, atrocious, immature, racist, and homophobic commenters would never have come into existence in the first place. It sickens me that people can behave this way in the comments section without repercussions.
If you engaged in this kind of behavior on Facebook or Instagram, you would be banned within just one day.
Oh, good Lord, this fandom. I used to be a part of it two years ago, and I admit I still occasionally check the SCP Foundation to see what's new. However, it's just lost its appeal. If you look past the edginess, you'll see that quite a few of the popular stories were lackluster, even before they got paired together so much that they lost what little horror they had in the first place. Most of the good stories I remember were not the "classics."
The worst part, though, is the kids who think this is the underbelly of the internet. They believe they're all cool and edgy for being down here. Now, I know I haven't seen the darkest depths of the internet, but I've certainly gone a lot deeper than reading stories about a guy who kills his family for no discernible reason. In general, if there are lots of people at the bottom of the internet, you're not really at the bottom of the internet.
Creepypasta is a very dark corner of the internet, based on myths, haunted video games, disturbing videos, and stories that sometimes appear in the news. I recommend reading one of the first stories, like Jeff the Killer, Ben Drowned, The Slenderman, Laughing Jack, or Eyeless Jack, for a good start.
To become part of the Creepypasta community or fandom, you need to have a favorite Creepypasta character to socialize with others in the community, or even cosplay as your favorite character! To popularize the fandom, you can easily share it with your friends, and hopefully, they can decide to join in.
The actual biblical passage says, "A man shall not lie with another man as he would with a woman." So, by the Bible's own admission, there is nothing wrong with being gay. Just make sure you don't put your penis in another man's vagina.
As a Catholic, I will never understand the hatred against gay people. Sure, the Bible says it's wrong, but God and Jesus would still love gay people if they are nice and do nothing wrong. And God would be ashamed of His children for being so awful to people for something they cannot help.
Besides, most of these Bible-bashers would be cheating on their loved ones, having sex before marriage, drinking out of moderation, getting angry, becoming envious, gambling, overeating, and committing other sins. Yet they still think they're holy and believe gay people will burn in hell. It's idiotic.
I added this to the list not too long ago, and it honestly needs to be higher. These individuals go around bashing people for being gay or lesbian, claiming it is against the Bible and is Satan's work. Ironically, they are going against the Bible themselves by sending death threats and forcefully asserting that being gay or lesbian is wrong. They even make foolish excuses, like saying gays and lesbians shouldn't be allowed to have children because they would be bad parents. The list could go on.
This group is also an embarrassment to all other phobias, giving them a bad name.
I used to be in this fandom, and it's toxic. The shipping wars are literally wars. If your ship differs from someone else's, you're immediately exiled. The worst part of the fandom is the lemons (smut). This is a children's book series about cats, and it's disgusting. Also, Scourge is an edgy, emo, badly developed character, but half of the fans love and ship him and will defend him relentlessly. Like most fandoms, it does have its good parts, like stunning animations, but the small number of toxic fans really are toxic.
I had never heard of this. I didn't know if this was an anime, something like those cat Valkyrie teenage girls, so I decided to look it up myself. Surprisingly, the franchise being a book was one of the last things I expected. I don't know anything about the fandom, but seeing it on the first page makes me think it's not going to be the best. I'll see what makes this fandom "bad." Though I'm not interested in cats at all, I'd rather have human characters instead of animals.
Almost every fandom I'm in is so hateful, and Nintendrones are no exception. They hate everything that isn't Nintendo and bully someone who likes something else. I think Soul Calibur is the best fighting game because of its creativity and vividness. But people in my old school hated me for liking Soul Calibur over Super Smash Bros. I like Super Smash Bros., but it's just an opinion. They need to calm down.
Please rank this higher. I used to be a huge fan of Nintendo, but now I can't stand the fans anymore, especially YouTubers like Mizzah Tee and CGRundertow. They're both entitled individuals who show no respect for anyone who likes anything other than Nintendo, and they completely dismiss any critics. I understand that people are entitled to their own opinions, but at least try to empathize with others instead of telling them to "shut up."
Don't get me wrong, I'm a big fan of Animal Crossing and The Legend of Zelda, but the Nintendrones can get a tad bit annoying. I consider myself a Nintendrone, but some, which I would estimate at about 25%, are usually rude kids around the age of 7-10 (not to offend people of that age) who self-proclaim as "pro gamers." They call anyone who doesn't know about the game they are talking about noobs or stupid. The only reason I am voting is for that estimated 25% of people.
I'm a Kpop fan myself. I've loved Kpop since middle school. It became a part of my life. However, 70% of the fandom is so freakin' toxic. They don't realize that idols are humans just like us and have feelings. You can't attack an idol just because "they look like another idol," "they're fat (while they have a body that everyone wishes for)," or "they're dating, talked to, or collaborated with your favorite idol." Many idols have suffered from depression due to huge hate and had to apologize for something they didn't even do!
There are some good fans of K-Pop. However, the dark side of this fandom is among the darkest on the Internet. Some are so obsessive that they go completely berserk at the sight of Jimin's eyes, even writing 200-word essays about how "hot" they are. There's an unwritten rule on the Internet: Do not mess with K-Pop fans. If you say anything negative about their idols, they may cancel you or even go as far as to send death threats to you and your family. This group has overshadowed the Bronies, Beliebers, or any other fandom in terms of toxicity.