Top Ten Best Characters In Mean Girls

1 Karen Smith

"it's like I have a 5th sense."

2 Regina George Regina Liliana George is the lead antagonist of the movie Mean Girls . She is portrayed by Rachel McAdams . ...read more.

3 Cady Heron

4 Janis

5 Damian

6 Gretchen Wieners

7 Ms. Norbury

8 Mr. Duvall

9 Mrs. George

10 Aaron Samuels

The Contenders

11 Mr. Heron

12 Mrs. Heron

13 Shane Oman

14 Glen Coco