1 Lori Quaid (Total Recall - 2012)
Lori Quaid is the hottest female villain. Love the character, she is selfish and manipulative. Sharon Stone's performance is more than honourable, she is very convincing and appealing... However, I've to say I created this entry with the specification of the year to refer to the Lori Quaid from the newest movie (with Kate Beckinsale in her dark tight outfit to stand her) and only to this one. - Toshin
2 Catwoman (Batman Returns)
Catwoman is a fictional character appearing in American comic books published by DC Comics, commonly in association with the superhero Batman.
3 Xenia Onatopp (GoldenEye)
Xenia Zirgavna Onatopp is a former Soviet fighter-pilot and the top assassin working for the Janus Crime Syndicate. She appears as the secondary antagonist in GoldenEye, and is played by Dutch actress Famke Janssen.
Kills in the nude during sexy time
4 Mystique (X-Men: First Class / X-Men: Days of Future Past)
5 Viper (Wolverine)
6 Baroness (G.I. Joe: The Rise of Cobra)
7 Emma Frost (X-Men: First Class)
Emma Grace Frost is a fictional character appearing in American comic books published by Marvel Comics, most commonly in association with the X-Men . The character first appeared in Uncanny X-Men #129 (January 1980), and was created by writer Chris Claremont and artist/co-writer John Byrne . Emma Frost, ...read more.
8 Poison Ivy (Batman & Robin)
Poison Ivy is a fictional supervillain appearing in American comic books published by DC Comics, commonly as an adversary of the superhero Batman.
9 Talia Al Ghul (Batman)
Talia al Ghul is a fictional character appearing in American comic books published by DC Comics, commonly in association with Batman.
10 Miho (Sin City)
11 Elle Driver (Kill Bill)
12 Harley Quinn (Suicide Squad)
Harley Quinn is a fictional character appearing in American comic books published by DC Comics, commonly as a sidekick of the Joker.
Ah hello hottest right here - Leofeldman
13 Santanico Pandemónium (From Dusk Till Dawn)
14 Lady Deathstrike (X2: X-Men United)
15 Baroness (G.I. Joe)
16 Lady X (Foodfight!)
17 Catherine Tramell (Basic Instinct)
18 Sil (Species)
19 T-X (Terminator 3: Rise of the Machines)
20 O-Ren Ishii (Kill Bill)
21 Hedra Carlson (Single White Female)
22 Peyton Flanders (The Hand that Rocks the Cradle)
23 Adrian Forrester (The Crush)
24 Serleena (Men in Black II)