Best Major Acting Debuts

These kids were unknown until these movies came up.
The Top Ten
1 Edward Norton - Primal Fear Edward Harrison Norton is an American actor, filmmaker and activist. He has been nominated for three Academy Awards for his work in the films Primal Fear, American History X and Birdman.
2 Haley Joel Osment - The Sixth Sense Haley Joel Osment is an American actor. After a series of roles in television and film during the 1990s, including a small part in Forrest Gump playing the title character’s son, Osment rose to fame for his performance as a young unwilling medium in The Sixth Sense..
3 Abigail Breslin - Little Miss Sunshine Abigail Kathleen Breslin is an American actress and singer. She appeared in her first commercial when she was three years old and in her first film, Signs, at the age of five.
4 Linda Blair - The Exorcist
5 Anna Paquin - The Piano Anna Helene Paquin is a Canadian-born New Zealand actress. Born in Manitoba and brought up in Wellington, New Zealand, Paquin studied at Hutt Intermediate School and the Wellington Girls' College in New Zealand before moving to Los Angeles during her youth where she studied at Windward School and went ...read more.
6 Jesse Eisenberg - Roger Dodger Jesse Adam Eisenberg is an American actor, author, playwright, and humorist. He made his television debut with the short-lived comedy-drama series Get Real.
7 Emma Stone - Superbad
8 Mike Myers - Waynes World

Technically his debut was in Saturday Night Live.

9 River Phoenix - Stand By Me River Jude Phoenix, born River Jude Bottom (August 23, 1970 – October 31, 1993) was an American actor, musician, and activist. He was the older brother of Rain Phoenix, Joaquin Phoenix, Liberty Phoenix and Summer Phoenix.
10 Tatum O'Neal - Paper Moon
The Contenders
11 Orson Welles - Citizen Kane
12 Barkhad Abdi - Captain Phillips
13 Natalie Portman - Léon: The Professional Natalie Portman is an actress, film producer and film director with dual American and Israeli citizenship. Portman is best known for her roles as Padmé Amidala in the Star Wars prequel trilogy and Nina Sayers in Black Swan. She won an Academy Award, a Golden Globe Award, and a Screen Actors Guild Award, among other accolades, for her performance in the latter.

Excellent movie, excellent actress, excellent debut.

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