Top 10 Worst Non-Fatal Diseases and Conditions

When we come across the term 'worst diseases', we often think those that are often lethal and can kill us pretty quickly. But there are some diseases, which are not directly the cause of death, but can severely impair your life. Let's have a look at such diseases.
The Top Ten
1 Alzheimer's

While it is not directly fatal, Alzheimer's is absolutely soul-sucking as one lose the ability to manage the activities of daily living, and most precious of all, connection to the rest of humanity - awareness of the world, and one's place in it. The immeasurable sadness of families watching as their loved one detaches from the world right before their eyes. This disease is a nightmare.

When you can't remember your own name, I would want to die, but can't because it doesn't kill.

2 Epilepsy

Epilepsy is a neurological disorder characterized by recurring seizures. Epileptic seizures are episodes that can vary from brief and nearly undetectable periods to long periods of vigorous shaking and pain. Many patients with epilepsy lead lives restricted by the condition. They are often unable to drive, operate machinery, go swimming alone or take a bath if there is no one around.

3 Depression

I think we all know this one. Depression takes everything away from you. It makes it impossible to properly love and care for people. It makes it hard to get an education. It makes you so tired you fall asleep for hours despite not being physically tired. Or it can reverse and keep you awake all night. It will make your life miserable.

4 Complete Blindness

Complete Blindness means that you cannot see anything. You cannot see light. That is actually something really difficult to adapt to, and you are prohibited from doing pretty much all the stuff normal people do

5 Paranoid Schizophrenia

Schizophrenia causes people to have insane levels of paranoia and detach from reality. They mostly believe that they're persecuted by some very evil entity or that they are being hurt or being used by some super power. Schizophrenic people regularly have visual hallucination where they see things that aren't real and extremely disturbing.

There's no illness that can cause that much damage to a person. The patient is not dead, however they are not there anymore.

I have an uncle who believes on gangstalking, and I've tried everything I can to assure him that these are just delusions, and it's all rooted from his mentally ill father. Overall it's a hell of a ride to convince him out.

6 Narcolepsy

Narcolepsy is a long-term neurological disorder that involves a decreased ability to regulate sleep-wake cycles. Symptoms include periods of excessive daytime sleepiness that usually last from seconds to minutes and may occur at any time. About 70% of those affected also experience episodes of sudden loss of muscle strength, known as cataplexy. It's a severe impairment to normal life as narcoleptics are prohibited from doing many day-to-day activities and requite constant care.

7 Autism

Depends. I live a pretty normal life, but it's a wide range of conditions.

I'm fine, but I know that other's who have more serious forms are not as well off

8 Complex Regional Pain Syndrome

Complex Regional Pain Syndrome is a disorder of a portion of the body, usually the arms or legs, which manifests as pain, swelling, limited range of motion, and changes to the skin and bones. It may initially affect one limb and then spread throughout the body; 35% of affected people report symptoms throughout their whole bodies.

9 Locked-In Syndrome

Locked-in syndrome is a condition in which a patient is aware but cannot move or communicate verbally due to complete paralysis of nearly all voluntary muscles in the body except for vertical eye movements and blinking. Total locked-in syndrome, or completely locked-in state (CLIS), is a version of locked-in syndrome wherein the eyes are paralyzed as well.

10 Trigeminal Neuralgia

It is a disease that affects the nerves in the face region. If you have trigeminal neuralgia, even mild stimulation of your face �" such as from brushing your teeth or putting on makeup �" may trigger a jolt of excruciating pain.

The Contenders
11 End Stage Emphysema

It involves the gradual destruction of the air sacs in the lungs, making it progressively more difficult to breathe. It's not quite enough to kill you just yet but enough to make your life miserable. Imagine the feeling of drowning every single waking moment, or feeling absolutely short of breath every 5 steps. That's what end stage emphysema feels like.

12 GERD (Acid Reflux)
13 Bipolar Disorder
15 Arthritis
17 Multiple Sclerosis

Typically, the disease affects females in their early twenties and it is different for everyone. Some people can live for years with very few visible and emotional symptoms, while others, like me, were diagnosed at 24 and have a very severe case that limits our everyday activities. I can't work, walk my dog around the block, and the fatigue is inescapable. If I sleep less than 12 hours a night, I have a hard time. Treatment is extraordinarily expensive, and I have had the disease for 17 years. It has definitely cost my insurance company more than 1.5 million dollars. My brain works, but my legs, arms, and other normal bodily functions are not guaranteed. Since my diagnosis, I have had 44 MRIs and have taken 6 different medications.

18 Schizoaffective Disorder

I have schizoaffective disorder it is very frustrating!

19 Psychosis
20 Obsessive–compulsive Disorder
21 Down Syndrome
22 Dry Eyes
23 Hives
24 Borderline Personality Disorder
25 Meniere's Disease
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