1 Disco Stu (The Simpsons)
2 Charles Chicken (Foster's Home for Imaginary Friends)
3 Michael (Don't Hug Me I'm Scared)
4 Itchy (The Simpsons)
It's pretty crazy but it's a winner
5 Ren Hoek (Ren & Stimpy)
6 Jerry (Tom and Jerry)
Jerry Mouse is a fictional character and one of the title characters in Metro-Goldwyn-Mayer's series of Tom and Jerry theatrical cartoon short films. He is a mouse that gets chased by Tom, but tries to trick him so he won't catch him .
For me crazier is the cat
7 Luan Loud (The Loud House)
Luan Loud is a main character in The Loud House.
Luan is the fourth-oldest child in the Loud family and second youngest of the five older sisters, at 14 years old. Her most annoying habit is telling bad jokes and puns and pulling pranks.
Espically on April Fool's Day where she cranks up the craziness. - egnomac
8 Stone Cold (WWE Slam City)
By all accounts, he is crazy
9 Izzy (Total Drama)
10 Fanboy (Fanboy and Chum Chum)
? Freaky Fred (Courage the Cowardly Dog)
Freaky Fred is a fictional character from the Cartoon Network animated series, Courage the Cowardly Dog.
? Basil (Courage The Cowardly Dog)
11 The Red Guy (Cow & Chicken)
12 Professor Flan (Fanboy and Chum Chum)
13 Mabel Pines (Gravity Falls)
Mabel Pines is one of the lead characters of the Disney XD animated series Gravity Falls. The character is voiced by Kristen Schaal, and designed by the series creator, Alex Hirsch. She is inspired by Hirsch's own twin sister, Ariel Hirsch. She is a caring, boy-crazy 12 year old girl that moved to the ...read more.
14 Daffy Duck
Daffy Duck is an animated cartoon character produced by Warner Bros. Styled as an anthropomorphic black duck, the character has appeared in cartoon series such as Looney Tunes and Merrie Melodies, where he usually has been depicted as the best friend and occasional arch-rival of Bugs Bunny.
I think Daffy is the craziest next to All the characters from Spongebob.
15 Woody Woodpecker (The Woody Woodpecker Show)
Woody Woodpecker is an anthropomorphic animated woodpecker, inspired by the acorn woodpecker and also resembling the pileated woodpecker, who appeared in theatrical short films produced by the Walter Lantz animation studio and distributed by Universal Pictures.
16 Chum Chum (Fanboy and Chum Chum)
17 Bessie Hickenbottom (The Mighty B)
18 Stewie Griffin (Family Guy)
Stewart Gilligan "Stewie" Griffin is a main character from the animated television series Family Guy. Obsessed with violence and matricide, Stewie is the youngest child of Peter and Lois Griffin, and the brother of Meg and Chris Griffin.
19 The Rat King (Teenage Mutant Ninja Turtles)
20 Mr. Whiskers (Brandy And Mr. Whiskers)
21 Drew Pickles (Rugrats)
22 Kodos (The Simpsons)
23 Miss. Fowl (The Adventures of Jimmy Neutron Boy Genius)
24 Qui Gon Jinn (Lego The Yoda Chronicles)
25 Jason (The Crack)
26 Elmer (The Fairly Odd Parents)
27 Tom (Tom & Jerry)
Thomas "Tom" Cat is a fictional character and one of the title characters in Metro-Goldwyn-Mayer's series of Tom and Jerry theatrical cartoon short films.
28 Stu Pickles (Rugrats)
29 Jack Lassen (The Simpsons)
30 Filbert (Rocko's Modern Life)
31 Beavis (Beavis & Butthead)
Beavis is a fictional character. He is one of the young teenaged protagonists on the MTV animated series Beavis and Butt-head.
32 Heffer Wolfe (Rocko's Modern Life)
Heffer Wolfe is a fictional character on the cartoon Rocko's Modern Life and the comic book series of the same name.
33 Edward Bighead (Rocko's Modern Life)
34 Carl (Llamas with Hats)
HAA! I laugh every single time this guys comes on screen. He is funny.
35 The April Fool (Fairly Odd Parents)
36 Juuzou Suzuya (Tokyo Ghoul)
He is in an anime but the last time I checked that counts. He is so insane since he puts stitches in himself just to pick them out
37 Mittelt (High School DxD)
38 Raynare (High School DXD)
39 Dohnaseek (High School DxD)
40 Kokabiel (High School DxD)
41 Freed Sellzen (High School DxD)
42 Liang Qui (Canaan)
43 Alphard Alshua (Canaan)
44 Flare Corona (Fairy Tail)
45 Koko Hekmatyar (Jormungand)
46 Mildo (Jormungand)
47 Akeno Himejima (High School DxD)
48 Mr. Garrison (South Park)
Herbert Garrison is a recurring character in the American animated television series South Park. He is voiced by Trey Parker.