Top Ten Worst Diseases

The Top Ten Worst Diseases

1 Cancer

Cancer is a horrible disease! Some people in my entire family had cancer. I hope one day there is a cure for cancer. I wish cancer wouldn't kill so many people. I am so glad I haven't had cancer and I am only 15 years old.

I lost somebody to cancer. His name was David Bailey. Iam still missing him. Whenever I see his house I just cry. I used to blame his death on myself. Because before he died I was naughty. At least he is in a better place where angels and peace and doves and god and Jesus are

It attacks you from the inside out, terrible way to go... It destroys your bodies cells.

My grandpa died of cancer. When he was diagnosed with cancer, all I could was cry. The last time I saw him was at the hospital, surrounded by cables. The next day, I hoped he was getting better. But he wasn't. He never got better. I was so depressed I didn't go to his funeral. I hate cancer so much, I still wish that there are better treatments for it. I don't want to lose someone again. - LaST_LiGHT


freddie mercury died of aids its the worst thing going - rockit(primejive)

You can survive Cancer but you can't escape AIDS. - gamefreak198

can be spread through sexual contact, whereas cancer cannot.

The worst thing about it is that you don't know if you have AIDS until your immune system is almost or completely destroyed. So AIDS can basically weaken your body so that a mere cold can kill you. - An_Average_Person

3 Ebola Haemorrhagic Fever

Severe internal bleeding and at least a week of your organs being reduced to mush. Then after all the pain and suffering you die of hypovolemic shock from blood loss.

I must be really brave - I've read the Hot Zone while eating despite all the blood and gore of it. Ebola seems not only to be extremely lethal, it also seems to be quite fascinating. But of course, I always find the more deadlier germs/diseases more interesting than the milder ones.
Don't forget Ebola's sibling, Marburg - It's not as deadly as Ebola, but it still has a very high mortality rate and the same sort of symptoms. Nice or what?

I really think Ebola is bad. Possible, you can die in just 2 hours once you get it. Now there is a cure though. Black seeds and honey. In Africa, the sickness is spreading. I hope everyone gets cured. I consider ebola worser than cancer. I mean, cancer you have better chances of surviving. Ebola?! I don't now if people agree with me. You now in the Islamic religion, Mohammed said that black seeds and honey are the cure for every sickness but death. That could be the cure for aids as well.

If you don't fear death, go and walk into a biosafety level 4 facility. I guarantee you won't find AIDS or Cancer there. What you will find is the most frightening, terrifying disease known to man. You can pick a strain, but your chance of survival will always be the lowest possible.


Let me paint a picture for you: one day you go to pick up a pencil but you realize you're having a difficult time holding it. Eventually you realize you're having a hard time holding your fork to get food and your own mouth. You start having trouble walking so you need a cane to be able to walk. However, sooner rather than later you are no longer able to walk even with the help of the a cane. Your voice starts to fade as you find it difficult to be able to talk. The only thing you can do at this point is ask for people to take care of things like taking you to the bathroom or feeding you. Even then seemingly in the blink of an eye you are no longer able to swallow food. Being able to say one word becomes nearly impossible. Unable to speak eat or walk the last thing you are finally unable to do is to breathe. And this is how ALS kills you. It takes everything from you that makes you human. It leaves you with nothing. So yes this is my vote for the worst disease known to man. I wouldn't ...more - steelersrock7

This is absolutely terrible in fact I rather have cancer than die by this

Stephen Hawking and Stephen Hillenburg both died of this disease on the same year. Curse you ALS!

With cancer, there is hope that chemo or surgery will work and eradicate the cancer. With ALS, there's no hope at all. The only drug available is one that slows down the diseases progression, giving the patient a few more months of life. ALS is absolutely terrifying as you become trapped in a body that doesn't work. You feel isolated because there's no way to communicate with others without the help of a computer or other device. You can't move at all, and no one survives. ALS takes everything from you and even makes it impossible to control when you laugh or cry. It's the worst disease, and it's unstoppable for now.

5 Rabies

Anything worse than cancer, it's this disease (although diseases like kuru and all are bad too). Close to 100% mortality rate (the people that die from this). That means if you get it, you're practically dead (only 3 people survived it.

Have you see the videos of people with rabies trying to drink water and can't because of hydrophobia, pretty sad stuff. Worst part is that their basically doomed.

Everything else on this list has some kind of redeeming quality. Cancer can be treated and even cured, ebola lasts no more than a few days, aids and conditions like Parkinson's can be somewhat managed by medication. With rabies, there are no redeeming qualities, it is a slow agonizing death that lasts for days or weeks. Once your symptoms start showing up, there is no cure or treatment. The disease causes intense physical pain, but has an unparalleled emotional component that causes even the most rational human being to lose their grip on reality and devolve into being a rabid animal.

Rabies is scary. I've seen this episode of monsters inside me and this girl was having strange mood changes, trouble focusing eyes and collapsing into seizures and shaking and then she died.

6 Alzheimer's

People accidentally kills themself or commit suicide rather than dying directly. - LordWerwereop

It is a hopeless disease. There is no cure, no treatment, very little help or understanding. It strips the person you love of every dignity and ounce of themselves, reducing them to a vegetable. Not only that the people left behind watch this helpless. In any other disease medicines or food might be withdrawn if there was no symptom control. In this case you watch as they become childlike. Husbands and children become carers, carers with no hope or relief. Just when you think it can't get worse it does. My mum has had Alzheimer approx 6 years she is 61 she will die old, 70-80 but really she die died years ago. Now we just watch and care as best we can as the depression, agitation, hallucination and language reduce as well as incontinence and other physical symptoms.
This person looks old, not like the picture I see in my head when I think mum. This person looks at me like she has never seen me unlike the mum I remember. There is so much more to say but I do not have the words to ...more

My mom was recently diagnosed but I already feel like she is in the mid to late stages. She can't finish a sentence, often gets confused about where she is, and has started to forget her family.

I always thought that I would one day lose my mom to cancer. Which isn't any better than Alzheimers but I at least thought I would be able to have a good, coherent goodbye with her. Because Alzheimers can't be officially diagnosed until an autopsy after the patient has died, this diagnosis came really late for us.

At this point, she doesn't really understand the disease that she has and it's too late to say my goodbye.

On top of that, knowing it's only going to get worse, more painful every day for years, is almost more than I can bear. My heart aches for my step dad and what he has to go through every day and my heart aches for my mom. I always wonder about what's going on in her head and how confused and scared she must be. And there's no one in the world who can pull ...more

My friend has a grandmother going through this. His grandmother has dementia and on the day of his grandfathers funeral, she didn't know what was going on. Just told them they had to be quiet because otherwise the Russians would find them. And that her dad locked the barn so they wouldn't find them. (She grew up in Germany, WWII)

She would ask for her husband a few times and my friend would tell her that he went for a walk. They would just make stuff up every time because immediately she'd forget it.

Then, when they were at the cemetery during the ceremony, when she saw the picture of her dead husband, she realized finally what was going on. She realized the man she loved for 60 years had died.

And 5 minutes later, she was back to normal. The man she loved for 60 years, he didn't exist anymore. He never existed. Erased from her memory.

And she was back in the barn, hiding. Being quiet so the Russians wouldn't find her. - styLIShT

7 Fatal Familial Insomnia

no cure for this disease prevents you from sleeps slowly eats away at the thalamous and eventually kills you its the worst prion disease if one member of your family has it you have a 50/50 chance of getting it - Elvisjackson

There's a reason why this is said to be the worst disease you could possibly get. Being diagnosed with this horror most be the most terrifying feeling ever as it's completely incurable as of now - what's worse than being doomed to slowly die, facing paranoia, hallucinations and dementia along the way? - Entranced98

my grandmothers side carries this horrible gene. I've heard about my previous ancestors dying with it & witnessed my grandmother & uncle die with it. I pray that I am not a carrier of this gene.

Fatal Familial Insomnia. What can I say. Its incurable as of now, paranoia, insomnia, dementia... it's a horror. The lack of sleep will drive you mad, insane, make you hallucinate, and slowly drain the life out of you as your touch with the world and people around you is lost. Utterly Horrific.

8 Diabetes

I've had diabetes since two weeks after my first birthday, and I wouldn't wish this on the worst person on earth. I've taken over two hundred thousand needles from it, have three diseases caused by it, and have developed chronic depression due to hating my life with it, and extreme anxiety from being bullied as a child for having it. My body is just a big pin cushion, and I'm covered in scar tissue. When my bloods are low, I hallucinate, and when they're high, I feel so much pain that I want to die. It's the reason behind five suicide attempts, and the reason I have to go to therapy.
I've lost two aunts to diabetes, and my third is in the hospital, blind, paralyzed, with kidney failure from it. I've died four times and I'm not even twenty-one.
There is no cure for it, and my children have a fifty-percent chance of getting it. It weakens my body to the point that a small shove will bruise me, and I'll get sick at just the tiniest thing. Cancer at least has a cure, and get's ...more

I have this disease, type I, since I was 5 years old, now I'm 18 and couldn't be happier. Yes, I would prefer not to have this problem, I can't say it gives me no boundaries but comparing diabetes with cancer is not fair. Cancer does not have a cure, just like diabetes, but treatments for cancer are far more destructive, more difficult. As long as you do all the treatments carefully, you will have an amazing life, believe me. With cancer you have a much higher possibility of dying. I was lucky to have all the support from family and friends. I feel I can do whatever I want, and if someone asked me to choose between finding out diabetes cure or cancer cure, I would choose cancer, any time. It's not easy to live with diabetes, I know, I have lived the same reality you have, every day, for 13 years, I have cried and suffered with pain many times, but I live and I can experience everything, just like everyone. Don't let yourself down because you have diabetes, there isn't anything you ...more

I've had the real Diabetes (type 1) for over ten years now. Since I was seventeen I've been injecting myself on average 5 - 6 times a day and pricking my fingers and forcing blood out of the end so to test the sugar content of my blood. If I tally the total number of injections then I would estimate it to be almost 19, 000. Now remember that in those ten years I have not had a day off. Every day, more injections, into already bruised parts of my body. The bruising never goes, the humiliation of your own body turning against you and coming very close to killing you is too much. I've woken from the warped nightmares of hypoglycemic comas more times than I can remember and every new day is a test to prevent the next episode from being the last. There is no end to this disease, it will get you eventually.

I have type 1 diabetes since I was 14 and this type of disease ruined my life because I have to take a shot of 2 different types of insulin; humalog and lantus for 3-4 times daily, checking blood sugar level 3-4 times daily, if I don't use a insulin, I will have a very high blood sugar level that causes tiredness, lack of concentration, and poor and unhealthy weight, blindness, etc. and I need to buy the insulin at the pharmacy but it is extremely expensive even I have an insurance so that destroys my financials too. Also diabetes shrinks the lifespan that I may die on early age. I am really tired and annoyed of this disease that I have. I having a worst luck in my life. How may I able to survive this?

9 Schizophrenia

I don't blame people who don't understand it. I think each disease is horrible and cancer or ebola etc sound extremely painful. Suffering shouldn't be a competition and Schizophrenia along with other mental illnesses aren't the same type of pain as physical illness although it can have physical effects. Schizophrenia is something I never could've imagined the horror it caused me. I figured it was an excuse for criminals to escape jail or just druggies. I COULDN'T HAVE BEEN MORE WRONG! The horror is unimaginable from someone who hasn't experienced it. When it onset I heard someone outside screaming my name, I saw shadowy figures outside and I was convinced demons where after me, as embarrassing as it is I peed myself and started pacing and I attempted suicide because I thought demons where trying to send me to hell. It's very horrible, embarrassing (to explain to non understanding people), and drains all your senses...

Your thoughts are your worst enemy. Demonic spirits haunt you and control your life. Can't work full time because of stress. Trouble getting socially involved with friends-- little communication. It's like a nightmare you can't turn off. Medication can help but it won't take it away completely. Worst mental illness by far in my opinion.

Your in a world conspiracy, your memories shot, voices surround you, your in hell. Life is a dream, each day is strange, scary, everyone is demons. Can't tell if your alive or dead, all your senses messed up, your número uno target, insomnia, depression/joy. Conversation is weird, big shun from society, can't make friends, no one wants to date you, your mind isn't "yours". Many suicide attempts, aliens, demons, ghosts, psychics, jinn, demons, no truth, only schizo on planet, cursed, hated, people want to abuse you and take advantage of you. Generally have to collect disability. Like a life long LSD trip that you can't escape from, and no guide book or help because the voices don't really speak intelligible English. Basically it feels like you died and the world is waiting to collapse of you, your family, your neighbors. No escape, 5 suicide attempts, can't die, God's curse, infinite hell AKA Schizophrenia.

I have a severe case of schizophrenia. I have really scary hallucinations of all the five senses that are just as real as any real person or thing. The voices especially are so tormenting, derogatory and frightening often yelling and screaming, commanding me to kill myself and how to do it. I am often trapped in believing I will lose everything because of plots against me, that I am being poisoned or the like. The antipsychotic medication I take is poison to my brain and body though without it I would be in the psych hospital long term and even with the meds, I still suffer from symptoms as well as side effects. I can't trust my senses, thoughts or emotions to tell me accurate information about other people or other things in the world. I have gained over 100 pounds from the meds, have parkinsonian side effects as well as other side effects and other kinds of poor health, not just from the meds but the disease as well. There is a lot of stigma and not a lot of support.

10 Malaria

It may not be the strongest, but in terms of how many people it kills, Malaria is a disease that might as well just have been created by the Grim Reaper. Of all the humans who died, it is believed that about 50% of their deaths were attributed to Malaria. So to put things into context, the animal that causes more human deaths than any other aren't elephants, not crocodiles, not hippos, not even the HUMANS themselves. It's mosquitos. They cause more than a million deaths every year. Let the embarrassment sink in.

Even though there are tablets against this, many people who cannot afford these drugs easily die of malaria. It is worse then any other disease because the parasite injects the disease in without you knowing so you could get it and still not know.

Guys.. Half of the people who has ever died, has died from malaria. All should vote this as number 1 unless you're voting in that form of how much it ruins your life.

There is a cure but it is hard to get to work you have to do it at the right time

The Contenders

11 Huntington's

I watched my mother deteriate over 17 years before this destructive cruel disease killed her off. Now I am watching the same thing happen to my younger sister and its heartbreaking. She can only lie down day and night and is now starting to choke even on the milk shakes she can only feed on. She will soon have a tube through her stomach to feed her. This disease affects the nervous system and shrinks the brain. No one can be cured from this. It is a slow and awful way to die

River dance, that's funny but it is more like standing on 2 different waterbeds at the same time. Definitively in the top 5. The 3 top reasons for dieing from it are accidents, suicide and choking because you can't swallow

Someone I know has this disease and it's frightening for him, he simply doesn't know what to do with himself as his motor functions disappear and his moods fluctuate. He's such a nice man, I wouldn't wish this disease on my worst enemy.

This is very tough it was between this and ALS for me but Huntingtons is worse the ALS because you lose cognitive function at least with ALS the mind doesn't go away. This disease makes you gradually become a vegetable and lose your brain in the process and its genetic too. If someone is affected in your family you can easilely get it too it only takes one match of the gene. It's so devastating that some people don't want to know if they have it or not. It is by far the worst in disease in my opinion.

12 Cholera

The scientist who found out the cure tested it by actually infecting himself with cholera. Obviously it worked or else there wouldn't be a cure. That takes guts.

Yeah it sounds like the worst, losing up to 2 gallons of water a day through diarrhea and if that wasn't bad enough if you aren't hooked up to an iv the salt shock will kill you before the dehydration does.

They have found a cure to it but you can only get it in North America. - SuperBacca


13 Bubonic Plague

I know this old couple that was on Monsters Inside Me that had the Bubonic Plague. They live in Arizona and are okay now (THANK GOD). They got the disease from a FLEA. A FLEA. It scared me so much when I was at the hospital with them. The doctors refused to let me in, so I couldn't see them. I'm just so glad that they survived...

It has one of the highest total population kill ratings of all time


In my opinion this is the worst cause when you have it you usually don't even know it until it's way too late the only way to get rid of the sores is amputation it was really sent from hell

14 Parkinson's

My grandfather died of this disease. There is a sort of cure. If you fight and they get the dosage wright then you live longer. It a genetic thing and is actually passed through the mother but normally a man gets it. Early signs are hands shaking when you sit down and aren't doing things with your hands. I watched a man who could put me on his shoulders and laugh all day die on a hospital bed in a coma like state. He wasn't even alive long enough for the doctors to figure it out. It's bad, really bad.

The victims of the disease are not at fault for their condition and there is no cure, only symptom management, as far as I know. I don't know why rabies is ranked higher/worse than this. But then again there is a lot I don't know.

It makes you scared to walk, and you freak out around people as you think they may crash into you. Small children who used to be a delight to watch are now a constant threat that they may trip you

Horrid disease - an ongoing bereavement...

15 HIV

This list says "worst diseases" not deadliest, so who knows schizophrenia might be worse than hiv in that sense.

This is a virus, not a disease

It's Deadlier Than Schizophrenia

How is schizophrenia above this...?

16 Smallpox

Fever, and the bumps are pretty itchy, once you scratch blood and chemicals start coming out

Thank God that this disease is gone! (That's what others are saying. I REALLY hope it's true.)

Killed one third of the people that got it.

It's an often fatal disease that spreads like wildfire! - thunderstar1124

17 Crohn's Disease

My boyfriend suffers from Crohn's disease and he has done since he was 12 years old. He is now 25. This disease has spread from his mouth where his lips swell and he has ulcers and blisters that kept on reoccurring then it moved down to his chest and lungs where more ulcers appeared and he was unable to breath properly without being in pain. After it traveled down into his stomach and gave him multiple stomach ulcers which was unbearably painful when eating therefore the malnutrition began and hr drastically lost weight. To treat the Crohn's and this time he was on steroids which allowed him to gain weight but too much and for a young boy in secondary school was really difficult.

He eventually came off the steroids and got back to a healthy weight when the Crohn's then moved location to his anus causing terribly uncomfortable abscesses which were continuously coming back after being drained. The doctors where at a loss as to what to do as he began to loose all appetite, ...more

Crohn's Disease is a traumatic illness because of its unrelenting pain driven inward for the symptoms rarely are visible from the outside. As a sixteen year old female I dropped forty pounds in only a few short months, and my entire body was rendered weak and immobile at a mere 87 pounds. The pain from a Crohn's induced stricture felt like that of a labor contraction that lasted for over a month, and after being admitted to a hospital and undergoing surgery for an ostomy (intestines pulled through the abdominal wall and attached to an outer bag), I attest to the humility this disease has put me through in sentencing me to wear a poop bag. Not only that, but sepsis from undergoing a ileostomy that came unstitched (the most riskiest surgery in itself above even a heart transplant) left me in unbearable pain to the point of sedation, for even I to endure, for I have an extremely high pain tolerance! It suppresses one weak, arthritic, anemic, fatigued, blotchy, pale, malnourished, loss of ...more

I actually do have this one. It's not that terrible compared to a lot of the diseases on the list thanks to treatment but it's surely annoying and would've killed me if treatment didn't exist. A have tons of sores in my collons and it's annoying. Thankfully it's not too much of a suffering thanks to treatment - darthvadern

Definitely, worse than cancer

18 Swine Flu

Oh, come on. This disease was blown WAY out of proportion by the media. The swine flu is just like the normal flu. The only people that have died of this so-called "deadly" virus are people with terrible health care and terrible health in general who are living in close quarters, babies, and old people.

Lol, swine flu? I had this when I was 7(in 2009, where it was an epidemic). My friend also had it. You only die of this if you're old, an infant or baby, or have poor healthcare.

80 deaths and 100 cases as of today - ronluna

People underestimate this disease, it is VERY bad and serious. I learned that the hard way.

19 Coronary Artery Disease

I just now learned a heart attach is number 1 actualy

20 Yellow Fever

Damages your adrenal glands and your nervous system causing unirrational fears such as water and lots of people have been found dead after a yellow fever epidemic

It's irrational fears and it is bad untreated it can kill thousands of people

I got bit by a mosquito in Brazil and caught this, thank god that I am still here. - SoloPotato

I'm glad that my dad recently took a vaccination for yellow fever. - Animefan12


This disease has no causes, no preventions, no treatment, no warnings. If you get it, you will not know it. If your friend gets it, they will not know it, and neither will you.

Basically you die when you sleep. Don't search this disease up, just don't. It'll keep you up at night. - 50

22 Tetanus

It is on any surface if something gives you a puncture wound you will most likely get it it is also in spore form in your intestines - Orlemley

Why is some brown stain on metal so deadly? - amenyoussef

It's does not explain

I also got tetanus

23 Leukemia


Roman Reigns

Noooo!please don’t remind me! My uncle has leukemia!he lives in england. He is a very nice emoji equals one respect😭

24 Tourette's Syndrome

I have Tourette's but it's pretty mild compared to some of the stuff other people with Tourette's have to deal with. I jerk my head, I shake for a little second, and sometimes I make a weird noise. It's really embarrassing when in happens in front of people. But motor tics can be disregarded and overlooked when they're mild, and people can look at me as more than 'that twitchy kid'. But it sucks pretty bad when you're impulsive. I do stupid things I end up regretting every day. I don't take time to think about some of the things I do and when I get really pissed off and I kick stuff and bash my forehead into things. Also, sometimes I do it to try and impress my friends by crushing apples with my head. I do this to make my friends laugh all the time and most of the time I say to myself "That was so stupid, what is wrong with me" afterwards. And unfortunately, most people don't really know much about it. They just think of motor tics, but not the lack of impulse control for some ...more

Just how bad is it to live with uncontrollable reactions to certain things. To the point where people don't understand you, you get bullied and harassed, rejected from society with no real way of getting back in. The saddest part about Tourette's syndrome is that it doesn't have to be so bad. People could be more understanding of such matters, but society has perverted it like most everything else to where one who has it has no chances of living a normal life.

I have got it. People always make fun of you. Once this boy and a mob were chasing after me shouting; Tourette's freak, chips (which I say when I tic), creep I ran inside I was sobbing. Please don't freak out. At this I used an sometimes bite my hand. Because I fell cross at myself and my dad called me evil hearted and he used to slap me round the head when I ticked I am getting better now and getting help

Living with this is so hard. You get bullied and wake up multiple times in your sleep depending on the severity. Every second all you think about is moving or saying a certain thing but you hate it. My main tick is rolling my eyes and I have constant headaches from it and people don't like me because they think I'm rolling my eyes at them. People tell you to stop and to control it. It's impossible

25 Tuberculosis

This disease is the highest death toll in history, over 500 million died of it, the bubonic plague only killed about 200 million.

I have it its not pretty but have faith I fell a lot better now just don't give up keep fighting

Very sad and scary.

Sorry I feel a lot better

26 Typhoid

I've had typhoid before when I was 8. Had it the same time with salmonella, I'm going to tell you, it is horrible... - ItsDaWorldOfSNuGGLEZ

I got it and it was bad so far in the 18th century. Bad. Fever that can't lower fast

27 Epilepsy

Epilepsy is bad the reason why it is bad because you don't know when your going to have one which is a seizure that is what epilepsy really is I have them I had a seizure one time I was talking to my step dad and after I got threw talking to him I laid down and he came down to my house I went to sleep after I got threw talking to him I woke up and I on the couch I had dirt all over me and I had a black eye from were I had fell outside and what made it so bad I did not even know that I had even went outside but I did and I didn't realize it but my step-dad woke me up on the couch and said what happened to you and I said what are you talking about and he said well you have a black eye talking about me I said what I don't have a black eye.but I did and I I also had a couple of wrecks in a car from seizures.because I wasnt taking my medicine like I was post to be so that's why I was having my seizures but when I take my medicine I'm alright but I hope I don't have none taking my medicine ...more

I've taken a hockey puck to my face, and the pain was nowhere comparable to the anguish experienced due to tonic-clonic seizures. Anguish is a good word - not just pain, but pure intellectual agony of recollecting thoughts blown apart by a seizure.
Epilepsy ranks BELOW the FLU? This list is a JOKE. Have a few seizures and you'll know. People with epilepsy are GODS compared to human diseases that just cause PAIN. Epilepsy is PAIN BEYOND HUMAN COMPREHENSION. Pure mind-blowing pain. That's why it knocks you out. MIND-BLOWING PAIN.

Epilepsy turned my friend's neighbor into a vegetable with no memory, cognitive abilities and mobility. every time after an attack he is pretty much a new born child, you have to learn everything again, and he has these attacks on a daily basis. He actually used to be a really smart person before epilepsy. It's horrible when you come to think how such a disease can turn a person into a nobody. Sounds rough, but it's just like that.

I knew a 30 year old that died from a seizure during his sleep three months ago. He got epilepsy from a serious head injury as a child. Everyday was a million times harder for him and a challenge getting through day after day. People were shocked after he died that you could die from a seizure they didn't realise you can die from a seizure.My aunt has epilepsy also

28 Kuru

The other 100% mortality rate

Kuru kuru kuru miru ponponchi -lenny-

29 Stroke

Not a disease

It is the worst ever beacause box jellyfish give you it

30 Mad Cow Disease

Ok really is mad snail disease I ripoff of mad cow disease

31 Multiple Sclerosis

I have ms and I wish people /family could see what my husband and daughters see. For they see the pain the frustration when you can't hold a pen or fork, when your walking along then your in a heap leg less your speech is slurred, tingling in your feet, hands and legs, bladder problems, sight. Yet people /friends and family say there's nothing wrong with you. You look so well. Yet I know there is lots more to look forward to. It's my husband and daughters I feel for, as you can see the sadness and pain in their eyes

No cure. Progressive. Ridiculously expensive to manage. And still a very mysterious disease. I have MS. It has taken so much away from me. It affects everyone differently, but my pain (8/10 when uncontrolled) itching, burning, multilayered pain that is the worst in my upper right leg, never completely goes away. Never. Managed with meds, ice, a TENS unit...I can get it to a 3/10 on the pain scale...sometimes. But it never completely goes away. Never. And then there's the fatigue, depression, mood swings, confusion, balance issues, spasticity, soreness, weakness...and one of the worst parts is how it's "invisible". I HATE hearing, "You look fine". Of course I do. I'm tough and you need an MRI or autopsy to see my scars. So I live with little understanding or empathy. But my being attacked by my immune it's a virus that needs to be destroyed. One more time: my immune system is trying to destroy my brain, and there is no cure. There are a lot of ...more

MS effects you physically, emotionally, and cognitivly. Currently, I have seizures, spacticity, heat sensitivity, severe fatigue, poor motor skills in my hands, a limp, problems swallowing, bladder issues, and this skin hypersensitivity that feels like I'm being electrocuted every time I'm touched. I have short term memory and word recognition problems, which makes for a tough sell to potential employers.
However, the worst part is how it destroys me emotionally. I am apathetic about life. I don't really care about dying anymore because it would be easier than the future I'm up against. My boyfriend of 5 years is the only one who sees my suffering, every one else thinks I'm fine because I look normal. It is really hard on him not being able to do anything to make me feel better. He can't even touch me for months at a time. Not even a hug.
This isn't some disease I can fight and win or even fight and lose. This is a crippling, degenerative disease that only promises to get worse.

This can be big emotional, physical, financial setback for the patient and family of the patient.

32 Polio

I thought there was a cure for this. - username34

Those kids are so not lucky too have that cauze when you can't walk for a long time and those kids is like 5 years and they can't walk for the rest of ther lif, they can but they can only walk with some help and that's why I took this one :o


This disease sucks it doesn't mean Panda's its pronounced Pan-Dus and it stands for
Pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections And some people do end up not eating

I once saw a man with pandas eat bamboo

My sister has pandas, she makes noises like a duck

What the hell kind of name is that?

PANDAS stands for Pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections which is when a person is diagnosed clinically after a patient develops a number of behavioral and physical symptoms following a streptococcal infection such as strep throat, sinusitis, cellulitis and/or scarlet fever. - Thecyanryan

34 Lower Respiratory Infection
35 Lung Cancer
36 Asthma

My best friend had asthma and died because of it. One night she had an asthma attack at school and the teacher was so STUPID that she thought that she just had mucus in her throat. When she kept coughing nonstop, she finally brought in the school nurse. The school nurse was smart enough to call the hospital, but by the time she got there, she was dead

It really isn't that bad! You may have to go to the hospital every few years, but in the end it's not bad at all. I have a pretty healthy life even though I have asthma.

It's bad when people are around you like some teachers are dumb - donovanthorn

Severe asthma is life threatening.


If you get this sickness you die straight away

From the Middle East spreading to Hong Kong, SARS is one of the worst diseases

This is the worst trust me, my wife is a NP, she told me that if this gets out, we are done


38 Manic Depression

I'm so sorry. When it comes to this kind of thing, its good to know that someone is here supporting you. I know you have no idea who the heck I am, but I have hope for you. - username34

All mental illness are bad including this one...

Its feels bad

I had a family member with this and trust me its horrible it pulls your lives apart. lucky it can be fixed with medication.

39 Tay-Sachs disease

Correction; 1 in 3500

This here is one of the worst.
It happens to children. You become blind, deaf, retarded, unable to live without assistance. Oh and also, you develop epilepsy. As an ashkenazi Jew, there was a.3% chance that I had TSD. In the general population, the chance is 1 in 320,000. For us, it’s 1 in 3,000. Only about 20% percent rarer than charcot-Marie-tooth disease.

40 Influenza

It is scary such a common disease can kill a lot of people. - MChkflaguard_Yt

I had a little bird, his name was enza, I opened the window, and in flew enza (influenza)

Sadly enza was hit by a truck in 2019

He met a big bird, his name was Ezra, he crushed him with his talons, rest in peace Enza.

41 Dysentery

I love dysentery it feels good

"i love dysentery it feels good"

lol what

This and tree :P

Whhhat how can a desesise feel good. YOU ARE CRAZY!

42 Sickle Cell Anemia

This is one of the most PAINFUL diseases on earth.

Yes,I know it is.

Stay strong

43 Depression

Depression is tough. I had it for a while. Eventually I met my life partner and he kicked me out of it. He told me that it's my choice to take control of my life and to make the most of it, it's not anyone else's. So no, no one else is the cause for your bad run, no one else is the cure for your depression.
I found my 'cure' in understanding that we are all here for the simple reason that we will have an impact on other people whether we like it or not.
It's YOUR choice to be a positive or negative impact.
I realised that and I fought hard against the Devil and the negativity he was planting in my mind. I am strong now, and I fight every day to be a better person. Depression is 'curable'. You just have to realise that you do have a purpose, whether you like it or not.

It is the worst thing you can imagine. I would love to have cancer instead and die on that. What makes a depression so terrible? You don't have any positive feelings anymore and you think you will never have them again. All I can think of is death and tragedy for the ones I will lose. There can't be a god if there's such a thing as depression.

I suffer from depression. Let me just say that it destroys your happiness and will to live, and it eventually makes living unbearable. I'd rather have a disease that is curable, thank you very much.

If you can move on while depression, you are not depressed enough. While other illness kill people, depression make people kill their own self, died horribly without even any smile on the face. It also invite other serious illnesses. Even the temporary drugs come with serious side effect like kidney problems. What you think you can live on, this isn't.

44 Motor Neurone Disease

I think motor neurone disease should be at the top because it is a wicked disease that ravages your body in a matter of months it is incurable and usually fatal. It takes away your body movements and even your eating and speech are affected as well.

Can't understand why this illness has not previously been listed.A dreadful disease with no cure..leads to death.
The mind remains intact whilst the body slowly fails to function

One of the greatest people. Stephen Hawking, has this illness

Ignorance is a bliss. People has no idea how cruel is this disease. most if not all diseases cited has cure or at least a small short of hope or you slower it consideratly. In MND there is no cure, there is no hope. Death is certain, fast and will paralise and screw ( consume) totally the person. maybe if ignorance was not bliss people would donate more to help people who suffers with this and the researches about it.

45 Diffuse Intrinsic Pontine Glioma (DIPG)

A childhood tumor with a <1% chance of survival that makes up a fifth of childhood brain tumors is for some reason only 46. Smfh

It's basically a brain tumor that happens to be highly aggressive and affects the brain neurons terribly. Just to let you know, it affects children (Approx. age 3-7) and survival rate is 0%. Let that sink in for a while... - CrimsonShark

46 Elephantiasis

It is so sad people end up literally looking like elephants no laugh it is scary my brother has it it is terrible

Such a scary-looking disease. You can't lay down. My 4th cousin has it, but he is doing well (he is 47).

Is this a real thing...?


47 Colitis

My older brother has this along with crohns and it is actually serious! He had to have 3 operations just to stop pain and he has to take 14/17 tablets a day! This should be top 15

I have Ulcerative Colitis and there's blood, so.

48 Lupus Nephritis

I live with lupus I'm in constant pain ( every joint in my body) the fatigue is a killer, I have constant head aches, I have constant rashes over my body which become worse when exposed to sun light. I have the rash across my face, no pain relief seems to work. When a flare occurs I can't get out of bed some days.

My aunt died from lupus when I was five or four and she had three wonderful sons

My daddy has lupus

The constant pain, migraines, rash, fatigue, getting sicker longer and easier than most, and the flairs can attack suddenly anywhere in your body. I've had my lungs attacked so bad thatvthe EMTs thought I was having an aneurysm, I couldent breath well enough to walk 10 feet for a week I was bed ridden anc had to crawl to the restroom and kitchen.i think it should be lot higher on this list.

49 Arthritis

What is the solution

Hey "Akshay Kamra", this website is not for sharing phone numbers! If you want help, call a doctor! Is it like WE CAN HELP YOU?!?!

Because of the meds it would make the person have a low immune system and they could get sick very easily from any other diease in here and die from that diease

I m just 22 and have arthritis.. Not just arthritis but thyroid, oesteoporisis in neck, knee, cervical spondylisis, determitis, eds syndrome.. I am so unhappy with life..that I m thinking of a suicide please help doctors 7404130372 India Akshay Kamra

50 Pneumonia

I almost had pneumonia. Today, it was a cold and rainy day and when I went to school, it was cold and rainy. During Language Arts, my lungs were aching when my teacher was reading a story. I fell on the floor and people thought I was relaxing. I wasn't! Luckily, it cured for some reason, and I still wonder how. - TeamRocket747

Pneumonia is very scary, your lungs start to fill up, making it harder to breathe, my regards to people have/ Know people that have (or had) pneumonia

I had this when I was about 2 months old and was so close to dying. That was just one of many times I was very close to dying in my 16 years of life.

My mother almost died from this when she was a kid... - JakePlaid

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