Top Ten Worst Diseases


The Top Ten

1 Cancer

Cancer is a horrible disease! Some people in my entire family had cancer. I hope one day there is a cure for cancer. I wish cancer wouldn't kill so many people. I am so glad I haven't had cancer and I am only 15 years old.

I lost somebody to cancer. His name was David Bailey. Iam still missing him. Whenever I see his house I just cry. I used to blame his death on myself. Because before he died I was naughty. At least he is in a better place where angels and peace and doves and god and Jesus are

It attacks you from the inside out, terrible way to go... It destroys your bodies cells.

My nan and grandma died of lung cancer

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freddie mercury died of aids its the worst thing going - rockit(primejive)

You can survive Cancer but you can't escape AIDS. - gamefreak198

can be spread through sexual contact, whereas cancer cannot.

Nost danger than cancer.But too much worse.

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3 Ebola Haemorrhagic Fever

Severe internal bleeding and at least a week of your organs being reduced to mush. Then after all the pain and suffering you die of hypovolemic shock from blood loss.

I must be really brave - I've read the Hot Zone while eating despite all the blood and gore of it. Ebola seems not only to be extremely lethal, it also seems to be quite fascinating. But of course, I always find the more deadlier germs/diseases more interesting than the milder ones.
Don't forget Ebola's sibling, Marburg - It's not as deadly as Ebola, but it still has a very high mortality rate and the same sort of symptoms. Nice or what?

I really think Ebola is bad. Possible, you can die in just 2 hours once you get it. Now there is a cure though. Black seeds and honey. In Africa, the sickness is spreading. I hope everyone gets cured. I consider ebola worser than cancer. I mean, cancer you have better chances of surviving. Ebola?! I don't now if people agree with me. You now in the Islamic religion, Mohammed said that black seeds and honey are the cure for every sickness but death. That could be the cure for aids as well.

Ebola is definitely the worst and one of the most lethal diseases. It is treatable and short-term, but it can destroy someone in a short time with severe internal bleeding and organ failure. I think it should be higher than AIDS and Cancer. - PhoenixAura81

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With cancer, there is hope that chemo or surgery will work and eradicate the cancer. With ALS, there's no hope at all. The only drug available is one that slows down the diseases progression, giving the patient a few more months of life. ALS is absolutely terrifying as you become trapped in a body that doesn't work. You feel isolated because there's no way to communicate with others without the help of a computer or other device. You can't move at all, and no one survives. ALS takes everything from you and even makes it impossible to control when you laugh or cry. It's the worst disease, and it's unstoppable for now.

ALS is the worst of all diseases- it robs you of your body and dignity but leaves you with your mind. You are unable to communicate, use your limbs eat, swallow your own saliva or even hold up your head yet you know exactly what is going on around you. There is no cure and no fast death. I can not imagine a worse disease to get.

This is a horrid condition. A few friends had/have it. There are 4 types of Motor Neuron diseases out there 2 of which are fatal, one of which is not and one which is not fatal unless it mutates into one of the fatal two. ALS is one of the two fatal ones and unfortunately the most common motor neuron disease. In a few cases, ALS is not fatal and in a few other cases, people with ALS live longer than the usual 2 to 5 years (Stephen Hawkings being a famous example). But in most cases, it is a cruel and horrid death.

Probably the worst disease in the world

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5 Rabies

Have you see the videos of people with rabies trying to drink water and can't because of hydrophobia, pretty sad stuff. Worst part is that their basically doomed.

Everything else on this list has some kind of redeeming quality. Cancer can be treated and even cured, ebola lasts no more than a few days, aids and conditions like Parkinson's can be somewhat managed by medication. With rabies, there are no redeeming qualities, it is a slow agonizing death that lasts for days or weeks. Once your symptoms start showing up, there is no cure or treatment. The disease causes intense physical pain, but has an unparalleled emotional component that causes even the most rational human being to lose their grip on reality and devolve into being a rabid animal.

Rabies is scary. I've seen this episode of monsters inside me and this girl was having strange mood changes, trouble focusing eyes and collapsing into seizures and shaking and then she died.

I am deathly afraid of this. - Camaro6

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6 Alzheimer's

It is a hopeless disease. There is no cure, no treatment, very little help or understanding. It strips the person you love of every dignity and ounce of themselves, reducing them to a vegetable. Not only that the people left behind watch this helpless. In any other disease medicines or food might be withdrawn if there was no symptom control. In this case you watch as they become childlike. Husbands and children become carers, carers with no hope or relief. Just when you think it can't get worse it does. My mum has had Alzheimer approx 6 years she is 61 she will die old, 70-80 but really she die died years ago. Now we just watch and care as best we can as the depression, agitation, hallucination and language reduce as well as incontinence and other physical symptoms.
This person looks old, not like the picture I see in my head when I think mum. This person looks at me like she has never seen me unlike the mum I remember. There is so much more to say but I do not have the words to ...more

My mom was recently diagnosed but I already feel like she is in the mid to late stages. She can't finish a sentence, often gets confused about where she is, and has started to forget her family.

I always thought that I would one day lose my mom to cancer. Which isn't any better than Alzheimers but I at least thought I would be able to have a good, coherent goodbye with her. Because Alzheimers can't be officially diagnosed until an autopsy after the patient has died, this diagnosis came really late for us.

At this point, she doesn't really understand the disease that she has and it's too late to say my goodbye.

On top of that, knowing it's only going to get worse, more painful every day for years, is almost more than I can bear. My heart aches for my step dad and what he has to go through every day and my heart aches for my mom. I always wonder about what's going on in her head and how confused and scared she must be. And there's no one in the world who can pull ...more

My friend has a grandmother going through this. His grandmother has dementia and on the day of his grandfathers funeral, she didn't know what was going on. Just told them they had to be quiet because otherwise the Russians would find them. And that her dad locked the barn so they wouldn't find them. (She grew up in Germany, WWII)

She would ask for her husband a few times and my friend would tell her that he went for a walk. They would just make stuff up every time because immediately she'd forget it.

Then, when they were at the cemetery during the ceremony, when she saw the picture of her dead husband, she realized finally what was going on. She realized the man she loved for 60 years had died.

And 5 minutes later, she was back to normal. The man she loved for 60 years, he didn't exist anymore. He never existed. Erased from her memory.

And she was back in the barn, hiding. Being quiet so the Russians wouldn't find her. - styLIShT

Guys there is a cure for Alzheimer's check it up online. I have forgotten the name but I think they call it the memory loss protocol. this disease can only attack those from 45 years old and some 35 years old. I have done my best to tell u all I know about the Alzheimer's now with the cure it is not a really horrible disease and the cure is actually a really nice one I think it is a meal. I had this diseases when I was 75 years old I knew nothing but my wife and really smart brother helped me on it. some doctors will tell you that there is no cure no cause no way to prevent it but it's a lie they just want to eat up through your I am 96 yrs old and living a great life I have seen my grand children. and I am living a great life and we all forgot about Alzheimer's.

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7 Fatal Familial Insomnia

no cure for this disease prevents you from sleeps slowly eats away at the thalamous and eventually kills you its the worst prion disease if one member of your family has it you have a 50/50 chance of getting it - Elvisjackson

There's a reason why this is said to be the worst disease you could possibly get. Being diagnosed with this horror most be the most terrifying feeling ever as it's completely incurable as of now - what's worse than being doomed to slowly die, facing paranoia, hallucinations and dementia along the way? - Entranced98

my grandmothers side carries this horrible gene. I've heard about my previous ancestors dying with it & witnessed my grandmother & uncle die with it. I pray that I am not a carrier of this gene.

I got nothing to say about this disease and it's really that bad. - 50

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8 Diabetes

I've had diabetes since two weeks after my first birthday, and I wouldn't wish this on the worst person on earth. I've taken over two hundred thousand needles from it, have three diseases caused by it, and have developed chronic depression due to hating my life with it, and extreme anxiety from being bullied as a child for having it. My body is just a big pin cushion, and I'm covered in scar tissue. When my bloods are low, I hallucinate, and when they're high, I feel so much pain that I want to die. It's the reason behind five suicide attempts, and the reason I have to go to therapy.
I've lost two aunts to diabetes, and my third is in the hospital, blind, paralyzed, with kidney failure from it. I've died four times and I'm not even twenty-one.
There is no cure for it, and my children have a fifty-percent chance of getting it. It weakens my body to the point that a small shove will bruise me, and I'll get sick at just the tiniest thing. Cancer at least has a cure, and get's ...more

I have this disease, type I, since I was 5 years old, now I'm 18 and couldn't be happier. Yes, I would prefer not to have this problem, I can't say it gives me no boundaries but comparing diabetes with cancer is not fair. Cancer does not have a cure, just like diabetes, but treatments for cancer are far more destructive, more difficult. As long as you do all the treatments carefully, you will have an amazing life, believe me. With cancer you have a much higher possibility of dying. I was lucky to have all the support from family and friends. I feel I can do whatever I want, and if someone asked me to choose between finding out diabetes cure or cancer cure, I would choose cancer, any time. It's not easy to live with diabetes, I know, I have lived the same reality you have, every day, for 13 years, I have cried and suffered with pain many times, but I live and I can experience everything, just like everyone. Don't let yourself down because you have diabetes, there isn't anything you ...more

I've had the real Diabetes (type 1) for over ten years now. Since I was seventeen I've been injecting myself on average 5 - 6 times a day and pricking my fingers and forcing blood out of the end so to test the sugar content of my blood. If I tally the total number of injections then I would estimate it to be almost 19, 000. Now remember that in those ten years I have not had a day off. Every day, more injections, into already bruised parts of my body. The bruising never goes, the humiliation of your own body turning against you and coming very close to killing you is too much. I've woken from the warped nightmares of hypoglycemic comas more times than I can remember and every new day is a test to prevent the next episode from being the last. There is no end to this disease, it will get you eventually.

I nearly got this from too many sweets, no joke! If I had this for real, the worst things that could happen will be:

-dying from complications
-no more desserts
-pricking fingers for blood tests daily
-going blind

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9 Schizophrenia

I don't blame people who don't understand it. I think each disease is horrible and cancer or ebola etc sound extremely painful. Suffering shouldn't be a competition and Schizophrenia along with other mental illnesses aren't the same type of pain as physical illness although it can have physical effects. Schizophrenia is something I never could've imagined the horror it caused me. I figured it was an excuse for criminals to escape jail or just druggies. I COULDN'T HAVE BEEN MORE WRONG! The horror is unimaginable from someone who hasn't experienced it. When it onset I heard someone outside screaming my name, I saw shadowy figures outside and I was convinced demons where after me, as embarrassing as it is I peed myself and started pacing and I attempted suicide because I thought demons where trying to send me to hell. It's very horrible, embarrassing (to explain to non understanding people), and drains all your senses...

Your in a world conspiracy, your memories shot, voices surround you, your in hell. Life is a dream, each day is strange, scary, everyone is demons. Can't tell if your alive or dead, all your senses messed up, your número uno target, insomnia, depression/joy. Conversation is weird, big shun from society, can't make friends, no one wants to date you, your mind isn't "yours". Many suicide attempts, aliens, demons, ghosts, psychics, jinn, demons, no truth, only schizo on planet, cursed, hated, people want to abuse you and take advantage of you. Generally have to collect disability. Like a life long LSD trip that you can't escape from, and no guide book or help because the voices don't really speak intelligible English. Basically it feels like you died and the world is waiting to collapse of you, your family, your neighbors. No escape, 5 suicide attempts, can't die, God's curse, infinite hell AKA Schizophrenia.

I have a severe case of schizophrenia. I have really scary hallucinations of all the five senses that are just as real as any real person or thing. The voices especially are so tormenting, derogatory and frightening often yelling and screaming, commanding me to kill myself and how to do it. I am often trapped in believing I will lose everything because of plots against me, that I am being poisoned or the like. The antipsychotic medication I take is poison to my brain and body though without it I would be in the psych hospital long term and even with the meds, I still suffer from symptoms as well as side effects. I can't trust my senses, thoughts or emotions to tell me accurate information about other people or other things in the world. I have gained over 100 pounds from the meds, have parkinsonian side effects as well as other side effects and other kinds of poor health, not just from the meds but the disease as well. There is a lot of stigma and not a lot of support.

Not really a disease. It's a disorder, but not a disease.

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10 Malaria

It may not be the strongest, but in terms of how many people it kills, Malaria is a disease that might as well just have been created by the Grim Reaper. Of all the humans who died, it is believed that about 50% of their deaths were attributed to Malaria. So to put things into context, the animal that causes more human deaths than any other aren't elephants, not crocodiles, not hippos, not even the HUMANS themselves. It's mosquitos. They cause more than a million deaths every year. Let the embarrassment sink in.

Even though there are tablets against this, many people who cannot afford these drugs easily die of malaria. It is worse then any other disease because the parasite injects the disease in without you knowing so you could get it and still not know.

Guys.. Half of the people who has ever died, has died from malaria. All should vote this as number 1 unless you're voting in that form of how much it ruins your life.

This disease kills more people than any other disease.

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The Contenders

11 Huntington's

I watched my mother deteriate over 17 years before this destructive cruel disease killed her off. Now I am watching the same thing happen to my younger sister and its heartbreaking. She can only lie down day and night and is now starting to choke even on the milk shakes she can only feed on. She will soon have a tube through her stomach to feed her. This disease affects the nervous system and shrinks the brain. No one can be cured from this. It is a slow and awful way to die

River dance, that's funny but it is more like standing on 2 different waterbeds at the same time. Definitively in the top 5. The 3 top reasons for dieing from it are accidents, suicide and choking because you can't swallow

Someone I know has this disease and it's frightening for him, he simply doesn't know what to do with himself as his motor functions disappear and his moods fluctuate. He's such a nice man, I wouldn't wish this disease on my worst enemy.

There is a good thing now it's a cure...but it's quite disgusting transplanting a sheep brain in your head

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12 Cholera

The scientist who found out the cure tested it by actually infecting himself with cholera. Obviously it worked or else there wouldn't be a cure. That takes guts.

Yeah it sounds like the worst, losing up to 2 gallons of water a day through diarrhea and if that wasn't bad enough if you aren't hooked up to an iv the salt shock will kill you before the dehydration does.

They have found a cure to it but you can only get it in North America. - SuperBacca


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13 Bubonic Plague

I know this old couple that was on Monsters Inside Me that had the Bubonic Plague. They live in Arizona and are okay now (THANK GOD). They got the disease from a FLEA. A FLEA. It scared me so much when I was at the hospital with them. The doctors refused to let me in, so I couldn't see them. I'm just so glad that they survived...

It has one of the highest total population kill ratings of all time

In my opinion this is the worst cause when you have it you usually don't even know it until it's way too late the only way to get rid of the sores is amputation it was really sent from hell

I mean it killed half of Europe and had plague doctors so this is my choice - spiderfifty

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14 Parkinson's

My grandfather died of this disease. There is a sort of cure. If you fight and they get the dosage wright then you live longer. It a genetic thing and is actually passed through the mother but normally a man gets it. Early signs are hands shaking when you sit down and aren't doing things with your hands. I watched a man who could put me on his shoulders and laugh all day die on a hospital bed in a coma like state. He wasn't even alive long enough for the doctors to figure it out. It's bad, really bad.

The victims of the disease are not at fault for their condition and there is no cure, only symptom management, as far as I know. I don't know why rabies is ranked higher/worse than this. But then again there is a lot I don't know.

It makes you scared to walk, and you freak out around people as you think they may crash into you. Small children who used to be a delight to watch are now a constant threat that they may trip you


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15 HIV

This list says "worst diseases" not deadliest, so who knows schizophrenia might be worse than hiv in that sense.

This is a virus, not a disease

It's Deadlier Than Schizophrenia

What is a auto immues disease is

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16 Smallpox

Fever, and the bumps are pretty itchy, once you scratch blood and chemicals start coming out

Thank God that this disease is gone! (That's what others are saying. I REALLY hope it's true.)

Killed one third of the people that got it.

In school, I learned people can bleed from their eyes because of this disease. PLEASE.
HIGHER. - TeamRocket747

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17 Crohn's Disease

My boyfriend suffers from Crohn's disease and he has done since he was 12 years old. He is now 25. This disease has spread from his mouth where his lips swell and he has ulcers and blisters that kept on reoccurring then it moved down to his chest and lungs where more ulcers appeared and he was unable to breath properly without being in pain. After it traveled down into his stomach and gave him multiple stomach ulcers which was unbearably painful when eating therefore the malnutrition began and hr drastically lost weight. To treat the Crohn's and this time he was on steroids which allowed him to gain weight but too much and for a young boy in secondary school was really difficult.

He eventually came off the steroids and got back to a healthy weight when the Crohn's then moved location to his anus causing terribly uncomfortable abscesses which were continuously coming back after being drained. The doctors where at a loss as to what to do as he began to loose all appetite, ...more

Crohn's Disease is a traumatic illness because of its unrelenting pain driven inward for the symptoms rarely are visible from the outside. As a sixteen year old female I dropped forty pounds in only a few short months, and my entire body was rendered weak and immobile at a mere 87 pounds. The pain from a Crohn's induced stricture felt like that of a labor contraction that lasted for over a month, and after being admitted to a hospital and undergoing surgery for an ostomy (intestines pulled through the abdominal wall and attached to an outer bag), I attest to the humility this disease has put me through in sentencing me to wear a poop bag. Not only that, but sepsis from undergoing a ileostomy that came unstitched (the most riskiest surgery in itself above even a heart transplant) left me in unbearable pain to the point of sedation, for even I to endure, for I have an extremely high pain tolerance! It suppresses one weak, arthritic, anemic, fatigued, blotchy, pale, malnourished, loss of ...more

Definitely, worse than cancer

My aunt has this her life is completely ruined from it. I was tested and came out clear thank GOODNESS

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18 Swine Flu

Oh, come on. This disease was blown WAY out of proportion by the media. The swine flu is just like the normal flu. The only people that have died of this so-called "deadly" virus are people with terrible health care and terrible health in general who are living in close quarters, babies, and old people.

Lol, swine flu? I had this when I was 7(in 2009, where it was an epidemic). My friend also had it. You only die of this if you're old, an infant or baby, or have poor healthcare.

80 deaths and 100 cases as of today - ronluna

People underestimate this disease, it is VERY bad and serious. I learned that the hard way.

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19 Coronary Artery Disease
20 Yellow Fever

Damages your adrenal glands and your nervous system causing unirrational fears such as water and lots of people have been found dead after a yellow fever epidemic

It's irrational fears and it is bad untreated it can kill thousands of people

I got bit by a mosquito in Brazil and caught this, thank god that I am still here. - SoloPotato


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This disease has no causes, no preventions, no treatment, no warnings. If you get it, you will not know it. If your friend gets it, they will not know it, and neither will you.

Basically you die when you sleep. Don't search this disease up, just don't. It'll keep you up at night. - 50

22 Tetanus

It is on any surface if something gives you a puncture wound you will most likely get it it is also in spore form in your intestines - Orlemley

Why is some brown stain on metal so deadly? - amenyoussef

It's does not explain

I have tetatatatanus

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23 Leukemia


24 Tourette's Syndrome

I have Tourette's but it's pretty mild compared to some of the stuff other people with Tourette's have to deal with. I jerk my head, I shake for a little second, and sometimes I make a weird noise. It's really embarrassing when in happens in front of people. But motor tics can be disregarded and overlooked when they're mild, and people can look at me as more than 'that twitchy kid'. But it sucks pretty bad when you're impulsive. I do stupid things I end up regretting every day. I don't take time to think about some of the things I do and when I get really pissed off and I kick stuff and bash my forehead into things. Also, sometimes I do it to try and impress my friends by crushing apples with my head. I do this to make my friends laugh all the time and most of the time I say to myself "That was so stupid, what is wrong with me" afterwards. And unfortunately, most people don't really know much about it. They just think of motor tics, but not the lack of impulse control for some ...more

Just how bad is it to live with uncontrollable reactions to certain things. To the point where people don't understand you, you get bullied and harassed, rejected from society with no real way of getting back in. The saddest part about Tourette's syndrome is that it doesn't have to be so bad. People could be more understanding of such matters, but society has perverted it like most everything else to where one who has it has no chances of living a normal life.

I have got it. People always make fun of you. Once this boy and a mob were chasing after me shouting; Tourette's freak, chips (which I say when I tic), creep I ran inside I was sobbing. Please don't freak out. At this I used an sometimes bite my hand. Because I fell cross at myself and my dad called me evil hearted and he used to slap me round the head when I ticked I am getting better now and getting help

Worst thing a human can feel

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25 Tuberculosis

This disease is the highest death toll in history, over 500 million died of it, the bubonic plague only killed about 200 million.

I have it its not pretty but have faith I fell a lot better now just don't give up keep fighting

Very sad and scary.

Antibiotics can cure it but they come st quite a lot I live in England so mine are free. Most cases are contagious and are prewar easily most poor countries don't evdn check for TB it makes you swell as your stomach or lungs could be filled with fluid. It can kill you with or without treatment

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26 Typhoid

I've had typhoid before when I was 8. Had it the same time with salmonella, I'm going to tell you, it is horrible... - ItsDaWorldOfSNuGGLEZ

I got it and it was bad so far in the 18th century. Bad. Fever that can't lower fast

27 Epilepsy

Epilepsy is bad the reason why it is bad because you don't know when your going to have one which is a seizure that is what epilepsy really is I have them I had a seizure one time I was talking to my step dad and after I got threw talking to him I laid down and he came down to my house I went to sleep after I got threw talking to him I woke up and I on the couch I had dirt all over me and I had a black eye from were I had fell outside and what made it so bad I did not even know that I had even went outside but I did and I didn't realize it but my step-dad woke me up on the couch and said what happened to you and I said what are you talking about and he said well you have a black eye talking about me I said what I don't have a black eye.but I did and I I also had a couple of wrecks in a car from seizures.because I wasnt taking my medicine like I was post to be so that's why I was having my seizures but when I take my medicine I'm alright but I hope I don't have none taking my medicine ...more

I've taken a hockey puck to my face, and the pain was nowhere comparable to the anguish experienced due to tonic-clonic seizures. Anguish is a good word - not just pain, but pure intellectual agony of recollecting thoughts blown apart by a seizure.
Epilepsy ranks BELOW the FLU? This list is a JOKE. Have a few seizures and you'll know. People with epilepsy are GODS compared to human diseases that just cause PAIN. Epilepsy is PAIN BEYOND HUMAN COMPREHENSION. Pure mind-blowing pain. That's why it knocks you out. MIND-BLOWING PAIN.

Epilepsy turned my friend's neighbor into a vegetable with no memory, cognitive abilities and mobility. every time after an attack he is pretty much a new born child, you have to learn everything again, and he has these attacks on a daily basis. He actually used to be a really smart person before epilepsy. It's horrible when you come to think how such a disease can turn a person into a nobody. Sounds rough, but it's just like that.

You can lose your memory, and once I thought there was someone else in my home once when there wasn't.

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28 Kuru

The other 100% mortality rate

Kuru kuru kuru miru ponponchi -lenny-

29 Multiple Sclerosis

I have ms and I wish people /family could see what my husband and daughters see. For they see the pain the frustration when you can't hold a pen or fork, when your walking along then your in a heap leg less your speech is slurred, tingling in your feet, hands and legs, bladder problems, sight. Yet people /friends and family say there's nothing wrong with you. You look so well. Yet I know there is lots more to look forward to. It's my husband and daughters I feel for, as you can see the sadness and pain in their eyes

No cure. Progressive. Ridiculously expensive to manage. And still a very mysterious disease. I have MS. It has taken so much away from me. It affects everyone differently, but my pain (8/10 when uncontrolled) itching, burning, multilayered pain that is the worst in my upper right leg, never completely goes away. Never. Managed with meds, ice, a TENS unit...I can get it to a 3/10 on the pain scale...sometimes. But it never completely goes away. Never. And then there's the fatigue, depression, mood swings, confusion, balance issues, spasticity, soreness, weakness...and one of the worst parts is how it's "invisible". I HATE hearing, "You look fine". Of course I do. I'm tough and you need an MRI or autopsy to see my scars. So I live with little understanding or empathy. But my being attacked by my immune it's a virus that needs to be destroyed. One more time: my immune system is trying to destroy my brain, and there is no cure. There are a lot of ...more

MS effects you physically, emotionally, and cognitivly. Currently, I have seizures, spacticity, heat sensitivity, severe fatigue, poor motor skills in my hands, a limp, problems swallowing, bladder issues, and this skin hypersensitivity that feels like I'm being electrocuted every time I'm touched. I have short term memory and word recognition problems, which makes for a tough sell to potential employers.
However, the worst part is how it destroys me emotionally. I am apathetic about life. I don't really care about dying anymore because it would be easier than the future I'm up against. My boyfriend of 5 years is the only one who sees my suffering, every one else thinks I'm fine because I look normal. It is really hard on him not being able to do anything to make me feel better. He can't even touch me for months at a time. Not even a hug.
This isn't some disease I can fight and win or even fight and lose. This is a crippling, degenerative disease that only promises to get worse.

My pain is horrific

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30 Mad Cow Disease

Ok really is mad snail disease I ripoff of mad cow disease


31 Stroke

Not a disease

It is the worst ever beacause box jellyfish give you it

32 Polio

I thought there was a cure for this. - username34

Those kids are so not lucky too have that cauze when you can't walk for a long time and those kids is like 5 years and they can't walk for the rest of ther lif, they can but they can only walk with some help and that's why I took this one :o


I once saw a man with pandas eat bamboo

My sister has pandas, she makes noises like a duck

What the hell kind of name is that?

PANDAS stands for Pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections which is when a person is diagnosed clinically after a patient develops a number of behavioral and physical symptoms following a streptococcal infection such as strep throat, sinusitis, cellulitis and/or scarlet fever. - Thecyanryan

I have bad PANDAS and I think this should be in the top 5

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34 Lower Respiratory Infection
35 Lung Cancer

If you get this sickness you die straight away

From the Middle East spreading to Hong Kong, SARS is one of the worst diseases

This is the worst trust me, my wife is a NP, she told me that if this gets out, we are done

This list is a total JOKE. J O K E. Schizophrenia is actually ABOVE this?!?! Stop treating it like it can kill you on its own. Sure, you might have hallucinations, but SERIOUSLY?! This should be WAY higher. Ugh! I hate other humans sometimes.

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37 Asthma

My best friend had asthma and died because of it. One night she had an asthma attack at school and the teacher was so STUPID that she thought that she just had mucus in her throat. When she kept coughing nonstop, she finally brought in the school nurse. The school nurse was smart enough to call the hospital, but by the time she got there, she was dead

It really isn't that bad! You may have to go to the hospital every few years, but in the end it's not bad at all. I have a pretty healthy life even though I have asthma.

It's bad when people are around you like some teachers are dumb - donovanthorn

I have asmha I have only had a asmha attack once when I was 2 but in hospital it was bad cose there was a baby being abbused and it died and the mum cryed for a long time

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38 Manic Depression Manic Depression

I'm so sorry. When it comes to this kind of thing, its good to know that someone is here supporting you. I know you have no idea who the heck I am, but I have hope for you. - username34

All mental illness are bad including this one...

Its feels bad

It's a good band! :D

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39 Tay-Sachs disease

Correction; 1 in 3500

This here is one of the worst.
It happens to children. You become blind, deaf, retarded, unable to live without assistance. Oh and also, you develop epilepsy. As an ashkenazi Jew, there was a.3% chance that I had TSD. In the general population, the chance is 1 in 320,000. For us, it’s 1 in 3,000. Only about 20% percent rarer than charcot-Marie-tooth disease.

40 Creutzfeldt–Jakob disease

There is a cure for cancer. This disease you can't escape from and it lasts a very short time. - Curtis_Huber

CJD is a degenerative neurological disorder (brain disease) that is incurable and invariably fatal.


It's called mad cow disease

41 Influenza

I had a little bird, his name was enza, I opened the window, and in flew enza (influenza)

Sadly enza was hit by a truck in 2019

He met a big bird, his name was Ezra, he crushed him with his talons, rest in peace Enza.

42 Dysentery

I love dysentery it feels good

"i love dysentery it feels good"

lol what

This and tree :P

Whhhat how can a desesise feel good. YOU ARE CRAZY!

43 Sickle Cell Anemia

This is one of the most PAINFUL diseases on earth.

Yes,I know it is.

Stay strong

44 Motor Neurone Disease

I think motor neurone disease should be at the top because it is a wicked disease that ravages your body in a matter of months it is incurable and usually fatal. It takes away your body movements and even your eating and speech are affected as well.

Can't understand why this illness has not previously been listed.A dreadful disease with no cure..leads to death.
The mind remains intact whilst the body slowly fails to function

One of the greatest people. Stephen Hawking, has this illness

Ignorance is a bliss. People has no idea how cruel is this disease. most if not all diseases cited has cure or at least a small short of hope or you slower it consideratly. In MND there is no cure, there is no hope. Death is certain, fast and will paralise and screw ( consume) totally the person. maybe if ignorance was not bliss people would donate more to help people who suffers with this and the researches about it.

45 Diffuse Intrinsic Pontine Glioma (DIPG)

It's basically a brain tumor that happens to be highly aggressive and affects the brain neurons terribly. Just to let you know, it affects children (Approx. age 3-7) and survival rate is 0%. Let that sink in for a while... - CrimsonShark

46 Elephantiasis

It is so sad people end up literally looking like elephants no laugh it is scary my brother has it it is terrible

Such a scary-looking disease. You can't lay down. My 4th cousin has it, but he is doing well (he is 47).

Is this a real thing...?


47 Depression

Depression is tough. I had it for a while. Eventually I met my life partner and he kicked me out of it. He told me that it's my choice to take control of my life and to make the most of it, it's not anyone else's. So no, no one else is the cause for your bad run, no one else is the cure for your depression.
I found my 'cure' in understanding that we are all here for the simple reason that we will have an impact on other people whether we like it or not.
It's YOUR choice to be a positive or negative impact.
I realised that and I fought hard against the Devil and the negativity he was planting in my mind. I am strong now, and I fight every day to be a better person. Depression is 'curable'. You just have to realise that you do have a purpose, whether you like it or not.

It is the worst thing you can imagine. I would love to have cancer instead and die on that. What makes a depression so terrible? You don't have any positive feelings anymore and you think you will never have them again. All I can think of is death and tragedy for the ones I will lose. There can't be a god if there's such a thing as depression.

I suffer from depression. Let me just say that it destroys your happiness and will to live, and it eventually makes living unbearable. I'd rather have a disease that is curable, thank you very much.

I have chronic depression and there is no smiling and no sunshine. The world is grey, and nothing is enjoyable anymore. You spend everyday crying as you wish there was a way to smile again. Seeing the smiling kids at your school who have everything good going for them, while you feel alone and trapped in a world. It’s like being in a cage. I’ve been on meds since I was a small child and will be on them for the rest of my life. The guidance counselors at my high school are jokes with poor training. The only way to escape from this curse is to distract yourself and search desperately for people who see the world like you. People can make you happy, sad, in love, or want to die. It’s not simply your choice. If I had a choice, I’d be happy.

V 19 Comments
48 Colitis

I have Ulcerative Colitis and there's blood, so.

49 Dengue Hemorrhagic Fever

You get this virus by mosquito bites, similar like malaria

50 Lupus Nephritis

I live with lupus I'm in constant pain ( every joint in my body) the fatigue is a killer, I have constant head aches, I have constant rashes over my body which become worse when exposed to sun light. I have the rash across my face, no pain relief seems to work. When a flare occurs I can't get out of bed some days.

My aunt died from lupus when I was five or four and she had three wonderful sons

The constant pain, migraines, rash, fatigue, getting sicker longer and easier than most, and the flairs can attack suddenly anywhere in your body. I've had my lungs attacked so bad thatvthe EMTs thought I was having an aneurysm, I couldent breath well enough to walk 10 feet for a week I was bed ridden anc had to crawl to the restroom and kitchen.i think it should be lot higher on this list.

#44 are you kidding me?! only because it is a little known disease. trying to get diagnosed is as bad as the disease its self taking an everage of 6 years.

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